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While sad moments are inevitable, most people will eventually overcome sadness1
The vicious circle of depression and obesity
Adipose tissue secretes a range of immune cells that produce signaling proteins associated with inflammationThe intertwined and overlapping biological mechanisms between these two diseases act as causal factors, exacerbate each other's disease processes, and become trapped in a vicious cycle in which inflammatory factors and corticosterone are involved as key regulators
Figure 1: Vicious cycle mediated by inflammatory factors and corticosterone
2
Neurogenesis of Depression
It is currently thought that some brain functions may depend on a delicate balance between neuronal death and regeneration, as new neurons replace old ones that ageTherefore, neuroregenerative treatment options for depression are still a long way off
Figure 2: Adult Hippocampal Neurogenesis
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The pictures in the article are from the reference
