-
Ischemic stroke intravenous thrombolytic therapy, using rt-PA
Time of Update: 2022-09-30
Randomized controlled trials have shown that intravenous rt-PA thrombolysis within 3 hours of the onset of neurologic symptoms in screened patients with acute ischemic stroke is a very effective treatment (class A evidence) at a recommended dose of 0.
-
PNAS: Caring children may be smarter
Time of Update: 2022-09-30
Figure 2: Quality of care in early life is a potential mechanism to explain the effect of foster care interventions on FSIQ scores at 18 years of age.
-
JNNP: Application of prescription opioids in multiple sclerosis
Time of Update: 2022-09-30
0 percent of patients with multiple sclerosis but no mood/anxiety disorders took only one opioid, and 8.
0 percent of patients with multiple sclerosis but no mood/anxiety disorders took only one opioid, and 8.
-
Neurology: Enhanced imaging and language assessment for the treatment of primary progressive aphasia
Time of Update: 2022-09-30
Recently, a study published in Neurology sought to identify a new behavioral assessment that (1) distinguished logopenic from other variants with high accuracy, and (2) was associated with left superior temporal parietal lobe atrophy (previously shown to be associated with this variant).
-
Drowsiness is also a disease, for which two academics won this year's "Scientific Breakthrough Award"
Time of Update: 2022-09-30
According to the official website of the Science Breakthrough Prize, Emmanuel Mignot and Masashi Yanagisawa found that narcolepsy is caused by the loss of a small group of brain cells that release arousal-promoting substances.
-
Nature back-to-back mechanisms of function-specific regulation of HSP70 and treatment of neurodegenerative diseases
Time of Update: 2022-09-30
Wentink co-published an article entitled Molecular disp of amyloid disaggregation by human HSP70, the authors through nuclear magnetic resonance microscopy and other experiments, found the role of JDPs as a comolecular chaperone in the specific regulation of their binding to HSP70s, The specific molecular mechanism of HSP70 with broad-spectrum biological function was uncovered.
-
Ultra processed foods or brain damage! A 10-year study of 70,000 people by a team at Tianjin Medical University found for the first time that higher intakes of ultra-processed foods were associated with an increased risk of dementia
Time of Update: 2022-09-22
So, does UPF have an impact on human brain health?Recently, a research team led by Professor Wang Yaogang of the School of Public Health of Tianjin Medical University published important research results in the journal Neurology [1]: Higher UPF intake was significantly associated with a higher risk of dementia, while unprocessed or microprocessed foods were closely related to a lower risk of dementia compared with UPF intake.
-
Acyclovir in the treatment of shingles requires attention to these compatibility contraindications
Time of Update: 2022-09-22
When is it time to be wary of acyclovir causing AKI?Today, we're going to take a look at Dr. Abdullah's article in the journal Saudi Pharm J to see the incidence, patterns, and associated risk factors of AKI after intravenous acyclovir injection.
-
Large-scale studies have shown that people with blood type A have a higher risk of stroke before the age of 60
Time of Update: 2022-09-22
On August 31, 2022, a new study published in the journal Neurology linked a person's blood type to the risk of early stroke.
On August 31, 2022, a new study published in the journal Neurology linked a person's blood type to the risk of early stroke.
-
The "preference" of experimental mice for women and the "dislike" of men directly affected the results of drug development experiments
Time of Update: 2022-09-22
Next, the researchers assessed the effect of the experimenter's sex on the mice's response to ketamine administration.
Next, the researchers assessed the effect of the experimenter's sex on the mice's response to ketamine administration.
-
How to choose insomnia medication correctly? These 5 points to know!
Time of Update: 2022-09-22
*For medical professionals onlyFull of dry goods!Clinically often encounter many patients have difficulty falling asleep, early awakening, dreams and other symptoms, how to correctly choose insomnia drugs to become the basic ability of clinicians, the author consulted the insomnia drugs related literature, summarized as follows, hope to bring certain help to peers.
-
Classification, diagnosis and treatment of cerebral hemorrhage, this article clarifies!
Time of Update: 2022-09-22
(4) For high-risk patients prone to DVT (excluding cerebral hemorrhage caused by coagulation dysfunction), after hematoma stabilization, subcutaneous injection of low-molecular-weight heparin or unfractionated heparin 1 to 4 days after the onset of the disease can be considered to prevent DVT, but the risk of bleeding should be noted (grade II recommendation, grade B evidence).
-
How is memory loss diagnosed and treated in January? Expert experience sharing
Time of Update: 2022-09-21
Physical examination:Blood pressure: 140/90mmHg. Positive examination of the nervous system: clear consciousness, fluent speech, slow response, rough memory, decreased computing power, normal time and space orientation.
Physical examination:Blood pressure: 140/90mmHg. Positive examination of the nervous system: clear consciousness, fluent speech, slow response, rough memory, decreased computing power, normal time and space orientation.
-
Nature Neuroscience: fMOST helps build a global database of single-cell projectionomics
Time of Update: 2022-09-21
Click on the blue word to follow usThe prefrontal cortex (PFC) is the center of the mammalian brain's execution of advanced cognitive functions such as learning, memory, attention, and emotion. Comple
-
When the emergency department encounters a patient with vertigo, the main points of diagnosis and treatment are analyzed in one article
Time of Update: 2022-09-21
*For medical professionals only5 points to sort out the vertigo emergency points!Vertigo is one of the common symptoms of emergency department, often requires emergency doctors to quickly determine the cause behind vertigo, carry out symptomatic treatment, and more importantly, identify the emergency treatment that should be carried out in time, so that patients can be treated in the best time for intervention.
-
PNAS Pan's team reveals the genetic mechanisms of gender differences between instinctive and aggressive behaviors
Time of Update: 2022-09-21
Are gender differences in behavior genetically determined? It may be difficult for humans or other advanced organisms to find the single gene that determines the differences between the sexes in certa
-
Xuanwu Hospital team finds specific metabolic markers for peripheral blood AD!
Time of Update: 2022-09-21
RoC analysis results show that the changing combination of metabolites in these 11 can effectively distinguish between AD and control groups (Figure A below), AD and non-AD (Figure B below), as well as AD and other types of dementia (Figure C below).
-
Add a new proof – the combination of multiple blood biomarkers is expected to be an effective method for early identification of AD!
Time of Update: 2022-09-21
Last year, a cross-sectional study titled "Performance of Plasma Amyloid β, Total Tau, and Neurofilament Light Chain in the Identification of Probable Alzheimer's Disease in South China"1 Blood biomarker levels, including Aβ42, Aβ40, t-tau, and neural filament light chain (NfL), were measured in 277 AD patients and 153 healthy controls with normal cognitive function from southern China to assess the efficacy of plasma biomarkers in diagnosing AD in populations in southern China.
-
Cell Wrote textbook discoveries! This neglected organ may directly affect brain functions such as memory, sleep, and mood
Time of Update: 2022-09-21
The researchers used cilia-targeted serotonin sensors, showing that when neurons extending out of the brainstem release the chemical signaling molecule Serotonin from axons, receptors on the cilia receive signals that trigger a series of biochemical reactions within the cell, ultimately altering the genomic material in the nucleus, especially epigenetic states.
-
How can patients with cerebral hemorrhage address blood pressure variability? Nicardipin may be preferred
Time of Update: 2022-09-21
Figure 1 Comparison of mean BPV between different treatment regimensFrom this study, it can be seen that compared with labetalol or hydralazine, nicardipine can lower blood pressure more stably after spontaneous intracerebral hemorrhage, avoiding the adverse effects of excessive BPV on the prognosis of patients.
