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Diagnostic criteria for tuberous sclerosis
Time of Update: 2022-10-02
Multiple subependymal calcified nodules extend to the ventricle (radiologically confirmed)6.
Multiple subependymal calcified nodules extend to the ventricle (radiologically confirmed)6.
Multiple subependymal calcified nodules extend to the ventricle (radiologically confirmed)6.
Multiple subependymal calcified nodules extend to the ventricle (radiologically confirmed)6.
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Neurology: Exercise and Brain Activity Improve Cognition! The UCSD team found that mental activity is associated with increased reserves of thought speed, and the more physical activity a woman has, the faster the reserve of thought speed
Time of Update: 2022-10-02
Recently, Dr. Judy Pa of the University of California, San Diego, and her team of researchers published a study in Neurology[7] that the more physical activity they participated, the faster women's thinking speed reserved, but men did not observe this association.
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Does World Alzheimer's Day Whole Milk Accelerate Cognitive Decline in the Elderly?
Time of Update: 2022-10-02
Saturated fat hypothesisThe results showed that during the 2-year follow-up period, the high intake of whole milk in the elderly at high risk of cardiovascular disease was positively correlated with the incidence of cognitive impairment in the elderly with less milk intake.
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Redox Biology: Correlation between ROS and calcium ions in neurodegenerative diseases
Time of Update: 2022-10-02
On the one hand, calcium ions can produce a wide range of action by controlling membrane potential, regulating the production of ATP, and influencing proteins such as calmodulin or calmodulin; On the other hand, excessively high levels of calcium ions in mitochondria can also be effective in inducing and triggering cell death.
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The Cell Karl Deisseroth group reveals the rules by which the brain's reins encode reward information
Time of Update: 2022-10-01
Subsequently, the researchers used different mouse models (Tac1-Cre, Chat-Cre, Th-Cre, and Calb1-Cre) to verify the function of these subsets of rein nuclei neurons in vivo calcium imaging, and used the visuospatial task paradigm to study the characteristics of different reins nucleus cell types encoding reward information (Figure 2).
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New study: After becoming a father, the brain shrinks by 1%-2%
Time of Update: 2022-10-01
The study reported a collaboration of laboratories from Spain and California (USA) that collected structural neuroimaging data from 20 expectant fathers before and after the birth of their first child, and the Spanish sample also included a control group of 17 childless men.
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The latest research shows that taking a daily multivitamin can improve Alzheimer's disease
Time of Update: 2022-10-01
1016/S0140-6736(22)00847-9","0:\"%23a5a5a5\"],[20,"\n","24:\"idjj\"|7:1|direction:\"ltr\"],[20," "],[ 20, "\n","24:\"gX54"|direction:\"ltr\"],[20,"Researchers collected GBD data from men and women aged 15-95 years over a 30-year period from 1990 to 2020, and assessed the effects of alcohol consumption on 22 health outcomes, such as cardiovascular disease, cancer, metabolic disease, etc.
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Nature Neuroscience: Want to drink Coke after eating fried chicken? The Zhejiang University team found that a high-fat diet promotes the proliferation and activation of microglia, leading to inflammation of specific brain areas and greatly increasing appetite for sugars
Time of Update: 2022-10-01
APVT CaMKIIα-positive neural Ca2+ signal intensity under different conditions in each groupTo confirm that CaMKIIα-positive nerve activation in aPVT is involved in regulating obsessive-compulsive foraging behavior, the research team used optogenetic techniques to activate the aPVT CaMKIIα-positive nerve in normal diet mice, and found that the number of lever compressions in mice (ChR2-on) where aPVT CaMKIIα-positive nerves were activated was significantly higher than in mice in the unactivated group (ChR2-off) (Figure 6A).
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Radio wave devices can remotely track Parkinson's disease and treatment responses at home| Science and Translational Medicine
Time of Update: 2022-10-01
" Welcome to pay attention to the official public account of Science and click "Read the original article" to access the original English text to light up your "like" for medical researchClick on the blue word above and follow usAccording to a year-long study involving 50 participants, scientists have created a new device that captures radio waves in patients' homes, which tracks the progression of Parkinson's disease and the effects of medications.
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STTT important progress! Wang Zhe/Song Weihong et al. of Capital Medical University have revealed the main mechanism of alzheimer's disease caused by lectin imbalance
Time of Update: 2022-10-01
Original link: _msthash="295880" _msttexthash="1946750">—END—The content is [iNature]iNatureAlzheimer's Disease (AD) is a neurodegenerative disease with insidious onset progressive, marked by amyloid β-β (Aβ) deposition to form neuritic plaque (NP).
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Prog Neurobiol Frontier Considerations on the Effects of Genetic Factors, Aging, and Intestinal Microbial Disorders on the Immune Response in Degenerative Retinal Degeneration of "Dry" and "Wet"
Time of Update: 2022-10-01
Authors - Yuan Xiangling, Chen Mei, Xu HepingEditor-in-Charge - Wang Sizhen Editor - Retinal degenerative diseases are a type of disease that eventually leads to loss of visual function due to the degeneration of retinal neurons or neurovascular units, including age-related macular degeneration (AMD), retinitis pigmentosa (RP), diabetic retinopathy (DR) and glaucomatous retinopathy, among others.
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The PNAS Wen Zilong/Xu Jin collaboration reveals a novel molecular mechanism by which microglia enter the brain
Time of Update: 2022-10-01
Microglia are tissue-specific macrophages of the central nervous system that play a very important role in the development, function, and homeostasis maintenance of the central nervous system [1]. Unl
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Professor Li Yan of the First Affiliated College of Xi'an Jiaotong University and other "Gut Microbes" intestine-brain axis latest masterpiece! Uncover the potential of ADHD behind the intestinal bacteria pusher of the Gut Junwang Weekly
Time of Update: 2022-10-01
The study explored the effect of vertical transport of microbiota in maternal generations of gestational diabetes mellitus on the phenotype of glucose metabolism in the offspring | Gut Jun Weekly to learn a piece of knowledge to ensure a health ▼ Intestinal Jun Weekly [DrGut] ▼ Intestinal medicine field knowledge feast to give time to readIssue 234 | Intestinal Junzhou Weekly ADHD, cognitive impairment; Bacterial aging, metabolic diseases; Gut metagenomic characteristics of ADHD reveal low Bacteroides ovatus-associated host cognitive impairment.
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【Lancet】Fudan Brain-like Research Institute and Huashan Hospital Team: A new model accurately predicts the risk of dementia in individuals in the next 5-10 years
Time of Update: 2022-10-01
Based on artificial intelligence algorithms and biomedical big data, the research team developed a new dementia risk prediction model (called UKB-DRP); The model provides prospective predictions of the risk of all-cause dementia and its primary subtype (Alzheimer's disease) – enabling accurate predictions of an individual's risk of developing dementia over the next five, ten or even longer years.
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Science Translational Medicine: The "energy factory" of neurons in early Alzheimer's patients has dysfunction!
Time of Update: 2022-10-01
A recent study published in Science Translational Medicine by scholars at Imperial College and the University of Cambridge provides in vivo imaging evidence for the relationship between mitochondrial damage and endoplasmic reticulum stress and neuronal synaptic loss that are widespread in early Alzheimer's disease [5].
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How can Alzheimer's disease be diagnosed early? Professor Zhao Qianhua raised these points
Time of Update: 2022-10-01
*For medical professionals only, early diagnosis and early treatment are the key to intervening in Alzheimer's disease! Alzheimer's disease (AD), commonly known as "Alzheimer's disease", is a neurodeg
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"Science and Progress": The Peking University team isolated from the traditional Chinese medicine wild horse chase to the natural molecule for the treatment of neurodegenerative diseases!
Time of Update: 2022-10-01
The results showed that in the mouse model of Usp7WT, the expression of Iba-1 and CD68 stimulated by bacterial lipopolysaccharide stimulation was inhibited by EB, and EB was able to reduce branching points more effectively, protect the morphology of microglia, reduce the production of pro-inflammatory factors such as TNF-α and IL-6, and had significant neuroprotective effects.
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NBT Dai Qionghai's team broke through the photon noise limit to achieve real-time ultra-sensitive fluorescence imaging
Time of Update: 2022-10-01
The proper functioning of organisms depends on a series of space-time coordinated cellular and subcellular activities, and observing and recording these phenomena is the first step in understanding th
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How to use pregabalin? These 5 points should be mastered
Time of Update: 2022-10-01
*For medical professionals onlyAbstain from alcohol during medication!Pregabalin, as a new type of drug for the treatment of neuropathic pain, has been widely used clinically for the treatment of postherpetic neuralgia, fibromyalgia, diabetic neuropathy and so on.
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Early diagnosis and early treatment of cognitive impairment after stroke is the key, come and watch the big coffee point of view!
Time of Update: 2022-10-01
*For medical professionals onlyPSCI should be "early prevention, early detection, early treatment", and standardized medication helps patients recoverThe prevalence of stroke in China is 11,148/100,00
