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A&R: Treatment of oral and facial manifestations of juvenile idiopathic arthritis, recommendations based on an interdisciplinary consensus
Time of Update: 2022-09-06
Management of orofacial manifestations of juvenile idiopathic arthritis: Interdisciplinary consensus-based recommendations [published online ahead of print, 2022 Aug 30].
Management of orofacial manifestations of juvenile idiopathic arthritis: Interdisciplinary consensus-based recommendations [published online ahead of print, 2022 Aug 30].
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Gout is very particular about drinking water, are you drinking it right?
Time of Update: 2022-09-06
If you regularly drink soda water, it is recommended to reduce the intake of salt in your daily diet .
If you regularly drink soda water, it is recommended to reduce the intake of salt in your daily diet .
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Expert consensus on chronic disease management in patients with rheumatoid arthritis
Time of Update: 2022-09-06
RA is an autoimmune, systemic, chronic inflammatory polyarthritis for which there is currently no cure . As the course of RA progresses, patients will experience joint deformities, disability, and los
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X-linked agammaglobulinemia: signs and symptoms, etiology, epidemiology, diagnosis, and treatment
Time of Update: 2022-09-06
X-linked agammaglobulinemia (XLA) is an X-linked recessive genetic disorder that is a primary immunodeficiency disease caused by a developmental disorder of the B-cell series in humans.
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Home Life Guide for Patients with Rheumatoid Arthritis - Diet
Time of Update: 2022-09-06
Eating foods high in calcium is especially important for patients with rheumatoid arthritis .
Eating foods high in calcium is especially important for patients with rheumatoid arthritis .
Eating foods high in calcium is especially important for patients with rheumatoid arthritis .
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Rheumatology: Extended ultrasonography finds larger vessel involvement in giant cell arteritis patients
Time of Update: 2022-09-06
OBJECTIVE: To compare limited and more extensive ultrasonography (anteromedial ultrasonography, A2 ultrasonography) to detect large vessel (LV) involvement in patients with newly diagnosed giant cell arteritis (GCA) .
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ARD: Loss-of-function variants in SAT1 cause X-linked childhood systemic lupus erythematosus
Time of Update: 2022-09-06
Conclusions: This study identifies two novel SAT1 loss-of-function (LOF) variants, shows the ability of frameshift mutations to confer lupus, highlights the pathogenic role of dysregulated polyamine catabolism, and identifies SAT1 LOF variants for a new monogenic cause of SLE .
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Treating gout, all you want to know is here!
Time of Update: 2022-09-06
! Therefore, the "2016 Guidelines for Diagnosis and Treatment of Gout in China" pointed out that the stable control of the blood uric acid level of patients below 360 μmol/L (6 mg/dl) is helpful for relieving symptoms and controlling the disease .
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Is Rheumatoid Arthritis Curable?
Time of Update: 2022-09-06
It is recommended that patients with early symptoms such as morning stiffness and joint swelling and pain should go to the rheumatology and immunology department of the hospital for treatment in time .
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20 rumors about gout were all dispelled at once
Time of Update: 2022-09-06
(2) The pain during the attack is unbearable, and the patient reduces the behavior that causes high uric acid, such as stopping eating high purine food and bed rest.
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J Autoimmun: Left ventricular size and function associated with lupus anticoagulants in patients with systemic lupus erythematosus: an echocardiographic follow-up study
Time of Update: 2022-09-06
Left ventricular size and function in patients with systemic lupus erythematosus associate with lupus anticoagulant: An echocardiographic follow-up study.
Left ventricular size and function in patients with systemic lupus erythematosus associate with lupus anticoagulant: An echocardiographic follow-up study.
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ARD: ALPK1 gain-of-function mutations cause NF-κB-mediated autoinflammatory disease: functional assessment, clinical phenotype, and disease course in patients with ROSAH syndrome
Time of Update: 2022-09-06
Methods: This cohort study systematically assessed the inflammatory profile of 27 patients with ROSAH syndrome and investigated the impact of ALPK1 mutations on immune signaling .
Methods: This cohort study systematically assessed the inflammatory profile of 27 patients with ROSAH syndrome and investigated the impact of ALPK1 mutations on immune signaling .
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To treat gout well, these two indicators are indispensable
Time of Update: 2022-09-06
Video applet like, double-tap to cancel the like and watch, double-tap to cancel the view The diagnosis, treatment and even prevention of gout are inseparable from these two indicators - uric acid and uric acid .
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Science sub-journal: Dong Chen's team reveals a new mechanism for RORγt to maintain mature Th17 cell lineage
Time of Update: 2022-09-06
On August 26, 2022, the team of Academician Dong Chen from the Institute of Immunology of Tsinghua University published a research paper entitled: RORγt expression in mature Th17 cells safeguards their lineage specification by inhibiting conversion to Th2 cells in the journal Science Advances .
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A&R: Small-molecule inhibitors of nuclear export improve lupus by modulating plasma cell production and survival
Time of Update: 2022-09-06
42128 OBJECTIVE: To investigate the hypothesis that recently approved selective inhibitors of nuclear export (SINE compounds) for the treatment of refractory plasma cell (PC) malignancies may have potential in the treatment of lupus .
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The past and present of rheumatoid arthritis diagnosis and treatment
Time of Update: 2022-09-06
To overcome it, you must first understand it . Rheumatoid arthritis (RA) is an autoimmune disease with erosive joint damage as the main clinical manifestation, which can occur at any age; its basic pa
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Rheumatoid arthritis prefers these 6 groups of people, how to do early screening?
Time of Update: 2022-09-06
In addition, the susceptibility of blood relatives with other rheumatic diseases, such as Sjögren's syndrome, lupus erythematosus, scleroderma, and rheumatoid arthritis, will also increase accordingly .
In addition, the susceptibility of blood relatives with other rheumatic diseases, such as Sjögren's syndrome, lupus erythematosus, scleroderma, and rheumatoid arthritis, will also increase accordingly .
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Rheumatology: Predictive value of the adjusted global APS score for clinical recurrence in patients with antiphospholipid syndrome, a longitudinal study
Time of Update: 2022-09-06
1093/rheumatology/keac485 OBJECTIVE: To assess the effect of mean adjusted global APS total score (aGAPSS) on recurrence of clinical manifestations in patients with antiphospholipid syndrome (APS) in a retrospective longitudinal study .
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【CLEAR A Daily Case】Gout
Time of Update: 2022-09-06
Secondary gout(1) Rare causes of imaging-visible disease(2) Myeloproliferative diseases, such as (eg): polycythemia vera, leukemia, lymphoma, and multiple myeloma(3) Cachexia(4) Myxedema, hyperparathyroidism(5) Chronic renal failure(6) Glycogen storage disease(7) Myocardial infarction(8) Lead poisoningStaging1.
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ARD: Behçet's disease risk variant HLA-B51/ERAP1-Hap10 alters human CD8 T-cell immunity
Time of Update: 2022-09-06
Conclusions: This study demonstrates that low activity ERAP1 alters immunogenicity to CD8 T cells, mediated by an HLA class I peptide set with under-trimmed peptides .
Conclusions: This study demonstrates that low activity ERAP1 alters immunogenicity to CD8 T cells, mediated by an HLA class I peptide set with under-trimmed peptides .