Rheumatoid arthritis prefers these 6 groups of people, how to do early screening?

At present, the incidence of rheumatoid arthritis in China is 0.

Many people think that rheumatoid arthritis only occurs in the elderly and is far away from them.

Are you in the following 6 susceptible groups? How to screen for early rheumatoid arthritis?

RA prefers these 6 groups of people

1.

As the name suggests, a humid environment plays a role in the onset of rheumatoid arthritis

From the point of view of traditional Chinese medicine, in a humid environment, "wind", "cold" and "dampness" are easy to invade the human body, block the meridians, and the poor circulation of qi and blood leads to soreness, numbness, flexion and extension of muscles, tendons, and joints.

2.

Among them, menopause reaches its peak and can be relieved during pregnancy.

All of the above indicate that the pathogenesis of rheumatoid arthritis is related to changes in the endocrine system, especially estrogen, and women with endocrine system disorders are more prone to rheumatoid arthritis

3.

The following drugs are associated with an increased incidence of rheumatoid arthritis, including: phenylbutazone, antiepileptic drugs, penicillamine, penicillin, reserpine, procainamide, phenytoin sodium, hydralazine, Chlorpromazine, the above drugs should be avoided as much as possible

According to research, it may be caused by the drug changing the antigen and causing the body to produce corresponding autoantibodies

4.

Relatives who are blood-related with rheumatoid arthritis, such as parents, grandparents, siblings, are more susceptible to rheumatoid arthritis

This is related to the human leukocyte antigen (HLA) carried by the patient, which is closely related to rheumatoid arthritis, and individuals who carry this antigen are susceptible to rheumatoid arthritis

5.

Cheerful personality is a protective factor for both men and women; studies have shown that RA occurs more often in family environments with high conflict, low aggregation, and low interpersonal communication

6.
People with autoimmune disorders

Studies have shown that people who have tonsillectomy are also more likely to suffer from the disease.
After tonsillectomy, the body's resistance to pathogens and the immune system may change, and immune pathological damage is likely to occur accordingly.
Therefore, the risk of rheumatoid arthritis is also high.
larger
.

How to screen for early rheumatoid disease?

1.
From a clinical perspective

If the wrist, metacarpophalangeal and proximal finger joints are swollen and painful (may be asymmetric in the early stage), and morning stiffness is obvious (the duration may be less than 1 hour), other diseases should be diagnosed and treated as rheumatoid arthritis
.

2.
If rheumatoid factor (RF) is negative

Anti-perinuclear factor (APF), anti-keratin antibody (AFA), anti-rheumatoid arthritis-33, anti-Sa antibody, anti-cyclic citrullinated peptide, anti-nuclear antibody, anti-Sm antibody, anti-RNP antibody, anti- Double-stranded DNA antibody detection (many indicators are used for differential diagnosis) to improve the specificity of early diagnosis of rheumatoid arthritis
.

3.
If X-ray examination is normal and symptoms persist

Magnetic resonance imaging (MRI) or ultrasonography of the joint should be performed, possibly to detect early synovitis changes
.

4.
Exclude related diseases with similar symptoms

other inflammatory arthritis (post-viral arthritis, reactive arthritis, enteropathic arthritis, psoriatic arthritis, ankylosing spondylitis, gout or pseudogout);

connective tissue disease (systemic lupus erythematosus, scleroderma, Behçet's disease, polyarteritis nodosa, undifferentiated connective tissue disease);

non-inflammatory joint disease (osteoarthritis, soft tissue rheumatism, or fibromyalgia);

Others: such as septic arthritis, polymyalgia rheumatica, subacute bacterial endocarditis,
etc.

If related discomfort is found, the diagnosis of early rheumatoid arthritis must be considered on the basis of excluding the above diseases under the guidance of a rheumatologist, and reasonable and effective treatment should be given
.