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Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with an increased risk of cardiac dysfunction
We included 108 patients with SLE: 90% were female, mean age 46±13 years, median disease duration 14 years (range 7-21)
During follow-up, two-fifths of echocardiographically measured diastolic function deteriorated (E/A ratio 1.
This study found that the presence of LAC was associated with measures of diastolic function and progressive LV dilation during the 5-year follow-up
Source: Myhr KA, Zinglersen AH, Hermansen MF, Jepsen MM, Iversen KK, Ngo AT, Pecini R, Jacobsen S.