-
The young man has multiple pains all over his body, but the rheumatism index is negative until the examination is completed...
Time of Update: 2022-09-09
Figure 1: Location and description of 18 anatomical tender points for fibromyalgiaTreatment principlesAt present, the treatment of fibromyalgia syndrome should be aimed at improving the quality of life of patients, and the diagnosis should be timely and accurate.
-
AS symptoms are repeatedly difficult to recover, how to deal with this annoying "goblin"?
Time of Update: 2022-09-09
Conclusion The repeated AS condition brings a lot of physical and mental pain to patients.
Conclusion The repeated AS condition brings a lot of physical and mental pain to patients.
Conclusion The repeated AS condition brings a lot of physical and mental pain to patients.
-
These 5 misunderstandings of systemic lupus erythematosus, have you been recruited?
Time of Update: 2022-09-09
The skin lesions of systemic lupus erythematosus often have different manifestations, such as erythematous papules, macules, discoid erythematosus, urticaria-like wheals, and even scaly papules and bullae after sun exposure, often accompanied by fever, Symptoms such as fatigue are easily misunderstood by patients and people around them as infectious skin diseases, and they are avoided .
-
First disclosure: Sjogren's syndrome coexists with these two diseases at the same time, and clinical vigilance is required
Time of Update: 2022-09-09
This case highlights the underlying lung manifestations of Sjögren's syndrome, as well as the organ involvement and disease associations that LIP and LCDD may cause.
This case highlights the underlying lung manifestations of Sjögren's syndrome, as well as the organ involvement and disease associations that LIP and LCDD may cause.
-
Toothaches can cause and aggravate rheumatoid arthritis, and this bacteria is involved!
Time of Update: 2022-09-09
*For medical professional reading reference onlyClinical knowledge points that rheumatologists cannot missThe People's Health Publishing House "Oral Science 9th Edition" clearly stated that periodontitis may cause and aggravate rheumatoid arthritis (RA), which may be related to the periodontitis bacteria prompting the immune system to produce anti-CCP antibodies.
-
Protecting kidney function: a true 'hard' endpoint for lupus nephritis patients
Time of Update: 2022-09-09
Tel: 010-58302828-6808Currently 1,130,000+ doctors have followed and joined us Yang XiangdongEarly treatment and active control do not have to "talk about wolf-like changes"Zhang ChongThe triple dilemma of preserving renal function in patients with lupus nephritisZhang JingboProteinuria to judge renal function is not perfect, eGFR to helpLi Ping4 magic weapons to solve easy relapse, low remission rate and adverse drug reactions8 special trains from 4 places to Beijing, Shanghai, Guangzhou and Hangzhou have set sail!
-
【Nature Sub-Journal】Natural mechanism leads to a 50-fold increase in T cell activation sensitivity!
Time of Update: 2022-09-09
This article is original from Translational Medicine Network, please indicate the source for reprinting Author: JeffIntroduction: Interactions between T-cell receptors (TCRs) and peptide major histocompatibility complex (pMHC) ligands are usually mediated by non-covalent bonds .
-
Cell Virulence Island helps bacterial immunity, and bacteriophages use the "island" to defeat the enemy
Time of Update: 2022-09-09
Written by | Look into the nightThe arms race between bacteria and bacteriophages is the main driver of evolution. Phage infections often lead to bacterial lysis, so the bacterial genome encodes the i
-
Nat Immunol's review comprehensively analyzes follicular helper T cells and their application prospects
Time of Update: 2022-09-09
Targeting cytokines also has the potential to promote TFH function in vaccination and infection .
Targeting cytokines also has the potential to promote TFH function in vaccination and infection .
Targeting cytokines also has the potential to promote TFH function in vaccination and infection .
-
Nature: After more than 20 years, the first physical connection map of the human immune system was successfully drawn
Time of Update: 2022-09-09
Using SAVEXIS, the researchers systematically mapped direct protein interactions across a recombinant library containing most of the surface proteins detectable on human immune cells .
Using SAVEXIS, the researchers systematically mapped direct protein interactions across a recombinant library containing most of the surface proteins detectable on human immune cells .
-
Nature Review: The role of extracellular vesicles in the immune system
Time of Update: 2022-09-09
These examples demonstrate that EVs can exert stimulatory effects through mediators (bioactive lipids, acute phase proteins, and cytokines), danger signals, transfer that affect innate immune cell activation, differentiation or polarization, recruitment, cytokine production, and various other effector functions.
-
ESC-Lancet: Beware of 19 autoimmune diseases, the risk of comorbid cardiovascular disease is too high!
Time of Update: 2022-09-08
Screenshot source: the LancetThe study finally included 446,449 patients with autoimmune disease as a disease cohort, all of whom were newly diagnosed with autoimmune disease from 2000 to 2017, and did not have cardiovascular disease within 1 year after diagnosis, and included 2102830 The general population served as the matching cohort .
-
Professor Li Xiaomei: Faced with the complex puzzle of Sjogren syndrome, innovative drugs are poised
Time of Update: 2022-09-08
In order to discuss the current situation of clinical diagnosis and treatment of SS and the latest progress in the field, the "Medical Community" specially invited Professor Li Xiaomei, Director of the Department of Rheumatology and Immunology of the First Affiliated Hospital of the University of Science and Technology of China, to express wonderful insights on related topics.
-
Advanced Science Peking University Li Zhanguo's research group discovered the molecular mechanism of tonsillar flora regulating the pathogenesis of rheumatoid arthritis
Time of Update: 2022-09-08
Thus, this study discovered the important role of tonsillar flora in maintaining immune balance, and the immunomodulatory mechanism of the antimicrobial peptide salivaricin in the pathogenesis of rheumatoid arthritis .
-
Four innovative drugs including the first TYK2 inhibitor are expected to be approved by the FDA in September
Time of Update: 2022-09-08
▲If you have any business needs, please long press to scan the QR code above, or▎Edited by WuXi AppTec Content TeamIn September, the FDA is expected to make approval decisions on the following four drugs, detailed in the table below .
-
To understand Chinese AS patients, reading this article is enough!
Time of Update: 2022-09-08
Looking back at the AS epidemiological surveys conducted in China over the past 15 years, the results are as follows:Three cross-sectional studies on the military population (54,474 in total) show that the prevalence of AS in the Chinese military population ranges from 0.
-
The Unforgivable Five Deadly Sins of Hyperuricemia: Not Just Gout!
Time of Update: 2022-09-07
The prevalence of CKD in patients with normal blood uric acid levels is about 11%, while HUA with CKD is as high as 32.
The prevalence of CKD in patients with normal blood uric acid levels is about 11%, while HUA with CKD is as high as 32.
-
J Autoimmun: Double B-cell targeted therapy improves autoimmune cholangitis
Time of Update: 2022-09-07
The combination of anti-BAFF and anti-CD20 treatment was more effective at reducing serum levels of anti-mitochondrial antibodies (AMA), total IgM, and IgG compared to mice treated with two separate drugs.
-
Chloroquine/hydroxychloroquine: an inflamma inhibitor in severe COVID-19?
Time of Update: 2022-09-07
To study the effects of hydroxychloroquine on NLRP3 inflammatory bodies, serum amyloid A (SAA) was used to stimulate human neutrophils and the secretion of IL-1β and caspase-1 (p20) was measured.
-
Escaped the crayfish, but did not escape it, the summer gout killers are here!
Time of Update: 2022-09-07
Video applet like, double-tap to cancel the like and watch, double-tap to cancel the view Many gout friends know that eating crayfish is very easy to induce gout attacks, so everyone keeps away from crayfish, but the attack rate of gout in summer is still high .
