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▎Edited by WuXi AppTec Content Team
Some autoimmune diseases are considered to be associated with an increased risk of cardiovascular disease.
Screenshot source: the Lancet
The study finally included 446,449 patients with autoimmune disease as a disease cohort, all of whom were newly diagnosed with autoimmune disease from 2000 to 2017, and did not have cardiovascular disease within 1 year after diagnosis, and included 2102830 The general population served as the matching cohort
▲Figure 1: 19 common autoimmune diseases and 12 cardiovascular diseases
Autoimmune disease patients are more likely to develop cardiovascular disease
The incidence of cardiovascular disease in patients with autoimmune diseases was 23.
▲Figure 2: The incidence and risk ratio of cardiovascular disease in patients with autoimmune disease and the general population by different subgroups (source of screenshot: Reference [1])
Autoimmune diseases were significantly associated with risk regardless of cardiovascular disease, with the highest associations being myocarditis, pericarditis, peripheral artery disease, and infective endocarditis
▲Figure 3: Cumulative incidence of cardiovascular disease in patients with autoimmune diseases and the general population (source of screenshot: Reference [1])
The higher the number of autoimmune diseases, the higher the risk of cardiovascular disease
The higher the number of autoimmune diseases, the higher the risk of cardiovascular disease.
Among the 19 autoimmune diseases, systemic sclerosis (HR=3·.
▲Figure 3: After stratification by the number of autoimmune diseases, the risk ratio of cardiovascular disease in patients with autoimmune diseases and the general population (source of screenshot: Reference [1])
Dr Nathalie Conrad, author of the paper, from the Faculty of Public Health and Primary Care, KU Leuven, Belgium, said: "Patients with autoimmune diseases have a similar cardiovascular risk to those with type 2 diabetes, and there are specific interventions for type 2 diabetes.
, but management for patients with autoimmune diseases is almost absent
.
”
Dr.
Nathalie Conrad hopes that through this study, patients with autoimmune diseases and medical workers will realize the importance of preventing cardiovascular disease
.
But knowing the truth, and even more so, the next step is to understand why patients with autoimmune diseases are more likely to suffer from cardiovascular disease than ordinary people, and how to take effective preventive measures
.
