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Preprint bans, previously unknown ancient humans and funders suppress research results
Time of Update: 2021-09-12
Adam Bloom, an archaeologist at the Australian Centre for the Study of Human Evolution at Griffith University in Brisbane, said: "This is the first time anyone has discovered ancient human DNA in that area .
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The latest PNAS article from Nanjing University: How a small protein can help flowers grow on time and correctly
Time of Update: 2021-09-12
In a new study published in the Proceedings of the National Academy of Sciences, researchers from Nanjing University and other places revealed the multiple roles of a small protein in ensuring that the reproductive organs of flowers are formed in a short time .
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Rare organochlorine pesticide by-products found in the liver of raptors
Time of Update: 2021-09-12
The ecological risk assessment of halogenated pollutants is an important issue because many of these chemicals persist in the environment, bioaccumulate through the food web, and may cause lasting adverse effects .
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Chinese scholars have made progress in the research of covalent organic frame membrane membrane distillation seawater desalination
Time of Update: 2021-09-12
Figure 1 (A) Schematic diagram of competitive reversible covalent bonding strategy; (B) Comparison of water transport channels in hydrophilic membrane, hydrophobic membrane, COF membrane a
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Liu Xingguo’s team from Guangzhou Health Institute identified molecular chaperones in the mitochondrial membrane gap
Time of Update: 2021-09-12
On August 31, Science China Life Sciences published online the latest research results of Liu Xingguo’s team at the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, "Short
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Science Revealed: How does a sudden, unexplainable heart attack happen?
Time of Update: 2021-09-12
"This technology allowed us to study a mutation adjacent to phosphorylation for the first time.
This discovery lays the foundation for further research on the effects of modifications on the proteins in heart cells and their response to drugs .
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Science: The same mutation occurs. Why do some cells form tumors?
Time of Update: 2021-09-12
ATAD2 forms a complex with the neural crest transcription factor SOX10, and establishes a chromatin state that is resistant to BRAF mutations .
in conclusion Overall, these data indicate that carcinogenicity is mediated by oncogenes (such as BRAFV600E), lineage-specific transcription factors (such as SOX10), and chromatin modifiers (such as ATAD2) that regulate development .
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Nature Cell Biology: Deubiquitinating enzyme OTUD3 regulates PTEN stability
Time of Update: 2021-09-12
The team led by researcher Zhang Lingqiang of the Academy of Military Medical Sciences discovered that the deubiquitinating enzyme OTUD3 maintains its protein level by removing the polyubiquitination of PTEN and inhibits tumor formation .
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The New England Journal of Medicine published the latest research results of Professor Wu Yangfeng showing that low sodium salt can significantly reduce stroke, heart disease and all-cause death
Time of Update: 2021-09-12
9" >The latest study by Professor Wu Yangfeng from the Peking University Clinical Research Institute and Professor Bruce Neal from the George Institute for Global Health found that as long as the Chinese people change the ordinary salt in the kitchen to low-sodium salt when cooking, they can significantly reduce the risk of stroke and heart disease.
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Are our friends determined by genes?
Time of Update: 2021-09-12
A team of researchers discovered that an enzyme mutation was found in the part of the brain that regulates emotions and motivation, which seems to control which mice want to socially interact with other mice—mice with similar genes prefer each other .
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Colon cancer risk is related to antibiotic use
Time of Update: 2021-09-12
“This study based on the registered population covered the entire population of Sweden and found a strong association between antibiotic use and a high risk of proximal colon cancer, as well as an inverse association with rectal cancer in women .
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Chinese scholars and overseas collaborators have discovered "magnetic beams" in magnetic materials with multi-topological charge characteristics
Time of Update: 2021-09-12
Funded by the National Natural Science Foundation of China (approval numbers: 51622105, 11804343, 11974021), the research team of Haifeng Du from the Center for High Magnetic Field Science of the Chinese Academy of Sciences, together with the team of Anhui University and the University of New Hampshire Zang Jiadong, proposed and experimentally verified a multi-topology magnetic charge structure .
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The team of Xiao Junyu and Xie Xiaoliang jointly discovered a powerful, fully human broad-spectrum neutralizing antibody combination against new coronavirus mutant strains
Time of Update: 2021-09-12
BD-813 binds to the back of the RBD, can directly block the binding to ACE2, and also maintains the activity against the Delta mutant strain .
Obviously, the L452R mutation in the Delta mutant strain will invalidate many neutralizing antibodies that target this region .
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Why is it so difficult for adults to learn a second language?
Time of Update: 2021-09-12
"By using electrodes on the surface of the brain to track high-resolution neural signals, the research team found that as listeners become familiar with unfamiliar sounds, clusters of neurons scattered in the language cortex seem to fine-tune themselves .
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Subiyi, a new diabetic foot drug, publishes important results in authoritative journals
Time of Update: 2021-09-12
"Regulating the efficacy of innovative macrophage drugs in the treatment of wounds in patients with diabetic foot ulcers: a phase three international multi-center randomized clinical trial" main content of the paper:Approximately 80% of lower limb amputations are caused by chronic diabetic foot ulcers (DFU), causing a heavy burden on medical care and medical expenses .
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Peking University researchers have discovered multiple potential new receptors that mediate SARS-CoV-2 invasion of cells
Time of Update: 2021-09-12
Through genome-wide CRISPRa functional screening, key host factors that affect SARS-CoV-2's entry into cells were discoveredCombining the SARS-CoV-2 pseudovirus and true virus experiments, the study found that the membrane proteins LDLRAD3, TMEM30A and CLEC4G can effectively mediate virus invasion into cells in a way that is independent of ACE2 .
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Researchers have discovered a link between the brain's opioid system and eating behavior
Time of Update: 2021-09-12
In their new study, researchers at the University of Turku in Finland investigated the link between opioid and endocannabinoid signals in the brain and different types of eating behavior .
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Immune cell betrayal explains why we become more susceptible to colds as we age
Time of Update: 2021-09-12
In a new study, they found that the fat tissues of old mice lost immune cell group 2 innate lymphocytes (ILC2), which are cells that restore body temperature in a cold environment .
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Novartis terminates phase II study of CD40 monoclonal antibody iscalimab for kidney transplant rejection
Time of Update: 2021-09-12
The results of the interim analysis showed that CFZ533 (iscalimab) is not as effective as tacromol in preventing organ transplant rejection in combination with other immunosuppressive agents (induction therapy, mycophenolate mofetil and corticosteroids) for patients undergoing kidney transplantation Division .
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Nature's new molecular device has unprecedented reconfigurability, reminiscent of the plasticity of the brain
Time of Update: 2021-09-12
T. Venkatesan, director of the Center for Quantum Research and Technology (CQRT) at the University of Oklahoma, a scientific subsidiary of the Gaithersburg National Institute of Standards and Technology, and an adjunct professor of electronic and computer engineering at the National University of Singapore, they added that their In the future, molecular devices may help design next-generation processing chips to increase computing power and speed, but the energy consumption is greatly reduced .