-
Chinese scholar mBio issued a paper: New Ramanome technology reveals the transformation network of single-cell metabolites
Time of Update: 2021-09-13
New ramanome technology reveals the transformation network from single-cell metabolites Researchers at the Single Cell Center of Qingdao Institute of Bioenergy and Process Technology, Chinese Academy of Sciences have developed a fast, low-cost and high-throughput technology that can analyze dynamic metabolic characteristics from only a homogenous cell sample .
-
What is the next step for human embryos grown in the laboratory?
Time of Update: 2021-09-13
"As a way to cross borders, researchers have developed a series of human embryo models in the past five years, most of which are formed from a mixture of stem cells .
-
Molecular Cell from Zhejiang University published a paper explaining the tumor immune mechanism of NF2 and its mutants
Time of Update: 2021-09-13
2021 Nian 8 Yue 27 days, hospital Xu Pinglong Laboratory in Molecular Cell on online published a report entitled entitled "Mutant Induced Phase Separation of NF2 imprisons at The CGAS-STING Machinery to abrogate antitumor Immunity" work describes the nucleic acid immune recognition signals cGAS-STING-IRF3 induces disease-related tumor suppressor protein NF2 to form cell aggregates through liquid phase separation, which regulates signal scale and tumor immunity .
-
Overview of the development of mRNA vaccines: part three
Time of Update: 2021-09-13
Figure 4 Exogenous mRNA triggers the innate immune response mechanism The mRNA vaccine synthesized by IVT can be recognized by PRR (including endosomal TLR3, -7, -8 and cytoplasmic innate immune receptors RIG-I and MDA5) .
-
For cardiovascular diseases, genetic testing is more effective than blood testing
Time of Update: 2021-09-13
Determining a person's blood type based on genetic tests rather than traditional blood tests can better understand the risk of cardiovascular disease .
A person's genetic variation plays an important role in the risk of cardiovascular disease .
-
Surprising: neurons in the visual cortex of the brain "drift" over time
Time of Update: 2021-09-13
Although other studies have demonstrated the "representation drift" of neurons in the brain related to smell and spatial memory, this result is surprising because neural activity in the primary visual cortex is considered relatively stable .
-
Experts predict that this winter will be "particularly difficult" to deal with the flu
Time of Update: 2021-09-13
Martin Michaelis, a professor of molecular medicine at the University of Kent, told the United Nations Express: “There is indeed a risk that we will face a severe flu season because the COVID-19 disease may affect the dynamics of human influenza viruses, and our prediction of influenza virus strains.
-
System upgrade my country has global tropical cyclone forecasting capabilities
Time of Update: 2021-09-13
After the version upgrade, China’s forecast range for tropical cyclones will be expanded from the previous Northwest Pacific and South China Sea to the world.
-
Results of Phase 3 HUYGENS study of Amgen's PCSK9 inhibitor cholesterol-lowering drugs announced
Time of Update: 2021-09-13
The HUYGENS study shows that: Compared with optimized statin therapy, Repatha combined with optimized statin therapy significantly improves the plaque stability of CAD patients by increasing the thickness of the fibrous cap .
-
First-in-class sounds good, not easy to do!
Time of Update: 2021-09-13
Me-too and Fast-Follow have spurred the rise of China's innovative drug field, but they have also been criticized by the industry due to the waste of clinical resources and the reduction in the rate of return on R&D investment .
-
Professor Yin Yuxin: A new mechanism for the anti-cancer gene PTEN family member PTENɑ to promote tumor immune escape
Time of Update: 2021-09-13
The research paper, for the first time, described the molecular mechanism of PTENɑ, a member of the PTEN family, that promotes tumor immune escape by reducing the sensitivity of tumor cells to host immune attacks .
-
Sub-Journal of "Science": Is the new design expected to equip CAR-T products with "enhancing agents"?
Time of Update: 2021-09-13
Recently, Science Signaling published a study in which the scientific team from the Fred Hutchinson Cancer Research Center took inspiration from T cell receptors (TCRs) and designed New CARs with higher antigen sensitivity have been developed, and they have shown better anti-tumor activity in mouse models of lymphoma, leukemia and breast cancer .
-
Tsinghua University published a paper revealing the molecular mechanism model of spCas9 protein search target
Time of Update: 2021-09-13
On August 20, 2021, Chen Chunlai and Liu Junjie’s research group from the School of Life Sciences of Tsinghua University jointly published a titled "Non-specific interaction between spCas9 and PAM downstream DNA sites to accelerate its target" in Chemical Science.
-
Nature Medicine: Brain tissue inflammation is the key to the progression of Alzheimer's disease
Time of Update: 2021-09-13
In order to determine the mechanism by which disordered tangles of tau protein fibers and amyloid plaques spread in the brain and lead to dementia, the researchers used real-time imaging technology to deeply study the brains of patients with Alzheimer's disease and healthy elderly people at different stages.
-
For the first time, it has been shown that silent mutations can predict the development of cancer cells
Time of Update: 2021-09-13
In the current study, based on about 3 million mutations in the cancer genomes of 9915 patients, researchers tried to determine the type of cancer and predict the probability of survival 10 years after the initial diagnosis-based only on silent mutations .
-
Chinese scholars have made progress in the research of storage-computing integrated devices
Time of Update: 2021-09-13
Focusing on this problem, a collaborative team such as Associate Professor Ye Lei and Researcher Hu Weida took a different approach and constructed a new type of homogenous transistor-memory device structure by using the physical mechanism of two-dimensional materials and the close neighbor coupling of the ferroelectric substrate .
-
Nature Microbiology: High numbers of viruses in the lungs lead to high mortality from COVID-19
Time of Update: 2021-09-13
"Our findings indicate that the body cannot cope with the large number of viruses that infect the lungs, which is largely the cause of deaths from COVID-19 in the pandemic," the lead author of the study and a part-time job in the Department of Medicine, New York University Langone School of Health Professor Imran Sulaiman, MD said .
-
Cell discovers the "hub" of immune cells hidden in tumors
Time of Update: 2021-09-13
Using these new analytical tools, the research team found that specific genetic programs and cell types are only present in MMRd tumors, which are more sensitive to immunotherapy .
Regev said: "Observing the co-mutation process in different cell types provides a new perspective for this complex tumor ecosystem .
-
Chinese experts discover new treatment targets for children with medulloblastoma
Time of Update: 2021-09-13
In vivo and in vitro experiments have shown that microRNA molecules derived from exosomes play an important role in the occurrence and development of childhood medulloblastoma, and can become a potential diagnostic and therapeutic target for children with medulloblastoma .
-
Cell Rep: Fundamentally prevent brain cancer
Time of Update: 2021-09-13
"The researchers discovered that a protein called galectin 1 interacts with another protein called HOXA5 to control the genetic programs that drive cancer stem cell behavior .
