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Researchers at McGill University have discovered the proteins that drive cancer stem cells
Due to its resistance to treatment, glioblastoma is the most common and aggressive brain tumor in adults
Researchers say that no matter how low the weeds are cut, if the roots are not uprooted, the weeds will grow back
Find the source of the problem
The researchers said that in all cancer cells, some cells play the role of stem cells, capable of self-replication and maintain the growth of cancer cells, just like normal stem cells usually renew and maintain our organs and tissues
"Our findings surprised us
The researchers discovered that a protein called galectin 1 interacts with another protein called HOXA5 to control the genetic programs that drive cancer stem cell behavior
The researchers also analyzed the patient database and found that glioblastoma patients with low expression of galectin1 and HOXA5 proteins have the best prognosis
Paved the way for new treatments
This discovery reveals the mechanism that regulates cancer stem cells
Original search:
DOI: https://doi.
Transcriptional Control of Brain Tumour Stem Cells by a Carbohydrate Binding Protein