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EP2 antagonists found what breakthroughs have been made in the treatment of inflammation in the past ten years?
Time of Update: 2021-10-11
Due to the lack of true selective EP2 antagonists at the time, their goal was to develop compounds that selectively inhibit EP2 receptors for studying brain inflammation caused by long-term epilepsy .
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Chinese Academy of Sciences: Monoclonal antibody targeting ace2 is a powerful broad-spectrum coronavirus blocker
Time of Update: 2021-10-11
This article reports a monoclonal antibody 3E8 against human angiotensin-converting enzyme 2 (ACE2), which can block SARS-CoV-2, SARS-CoV-2 variants, SARS-CoV-NL63 and other coronaviruses The S1 subunit and pseudotyped virus structure have no obvious effect on the physiological activity of ACE2, nor will it cause serious toxicity to ACE2 "knock-in" mice .
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Does large-scale genetics research on autism make sense?
Time of Update: 2021-10-11
jpg"/>            A large study based on genetics and autism spectrum disorder (ASD) in the United Kingdom (the Spectrum 10K study aims to collect the DNA of 10,000 autistic patients and their families) was suspended because some people criticized the study for failing to solve the problem.
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Artificial intelligence 3D printing technology solves the "invisible" problems in orthopedic surgery
Time of Update: 2021-10-11
Recently, Zhou Jianlin’s team, associate professor of bone and joint surgery at Wuhan University People’s Hospital, used artificial intelligence 3D printing technology to print out Aunt Zhang’s true positioning model of the acetabular and iliac bone defect, and through the customized guide "navigation" surgery, she accurately performed tumor resection.
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Hotview Bio-New Coronavirus (2019-nCoV) Antigen Self-Test Kit was registered by MHRA in the UK
Time of Update: 2021-10-11
On September 23, Hotview Bio issued an announcement stating that the company's new coronavirus (2019-nCoV) antigen self-test kit has recently been registered by the British Medicines and Health Products Administration (hereinafter referred to as "UK MHRA") .
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Reduce the number of injections per year by 86%. Long-acting growth hormone therapy is approved by the US FDA
Time of Update: 2021-10-11
Reference materials:[1] Ascendis Pharma A/S Announces US Food and Drug Administration Approval of SKYTROFA® (lonapegsomatropin-tcgd), the First Once-weekly Treatment for Pediatric Growth Hormone Deficiency.
com/news-release/2021/08/25/2286624/0/en/Ascendis-Pharma-AS-Announces-US-Food-and-Drug-Administration-Approval-of-SKYTROFA-lonapegsomatropin-tcgd-the-First -Once-weekly-Treatment-for-Pediatric-Growth-Hormone-Deficiency.
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New blood test method can predict patients with high risk of severe new coronary disease
Time of Update: 2021-10-11
According to a recent report on the website of the British "New Scientist" magazine, American researchers have invented a new blood test method that can help by measuring the corresponding antibody levels in the blood of people infected with the new coronavirus (targeting molecules released by dead blood cells and their DNA).
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The State Food and Drug Administration issued two guidelines for registration and review of medical device animal testing research
Time of Update: 2021-10-11
3. SecurityAfter the applicant adopts risk control measures, the safety of some products can be evaluated by animal test studies as appropriate, such as research on the safety scope of drugs in medical devices containing medicines, toxicological evaluation through histopathology, etc.
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RedHill accelerates research on new drug RHB-107
Time of Update: 2021-10-11
The South African Health Products Administration (SASAPRA) approved a phase 2/3 study of oral RHB-107 (upamostat) once a day in patients with new coronary pneumonia who have developed symptoms but do
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Innovative ADC therapy for ovarian cancer and triple-negative breast cancer enters the clinic
Time of Update: 2021-10-11
KAAG1 is a tumor-associated antigen that is highly expressed in most ovarian cancers and triple-negative breast cancers.
Reference materials:[1] ADC Therapeutics Doses First Patient in Phase 1 Clinical Trial of ADCT-901 in Advanced Solid Tumors.
com/press-releases/press-release-details/2021 /ADC-Therapeutics-Doses-First-Patient-in-Phase-1-Clinical-Trial-of-ADCT-901-in-Advanced-Solid-Tumors/default.
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Controlling hunger or fullness depends on the details of the atom
Time of Update: 2021-10-11
By determining the 3D structure of the protein, researchers from Charité University in Berlin were able to visualize the molecular structure of the protein-the melanocortin 4 receptor (MC4R)-the hormone that interacts with it .
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Nutrition is better than rice and noodles, but not the soybean grain amaranth
Time of Update: 2021-10-11
In recent years, grain amaranth has settled down in many parts of the country and has become a special food and feed crop in China .
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Researchers have developed a new and efficient data processing method
Time of Update: 2021-10-11
Unlike the logic operation assisted by charge and current, electrons do not need to move in information processing based on magnetism, so they consume less energy .
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Random trials prove that whole-genome sequencing can provide precise care for critically ill children
Time of Update: 2021-10-11
Ryan Taft, vice president of scientific research at Illumina, said: “This study shows that whole-genome sequencing of babies with suspected genetic diseases is possible in different clinical locations and patient populations .
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The effect of 3D printed vaccine patch is ten times stronger than traditional injection, and it can also complete the vaccination by itself
Time of Update: 2021-10-11
The lead author of the paper and Professor of Medicine at Stanford University, Joseph De Simon said: "The purpose of our development of this technology is to reduce the time for vaccine development, the dose used, and to relieve people's pain during subcutaneous injection .
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US FDA postpones IgAN therapy Nefecon decision date: potential for disease correction
Time of Update: 2021-10-11
Calliditas Therapeutics recently announced that the US Food and Drug Administration (FDA) has extended the Nefecon (budesonide) New Drug Application (NDA) "Prescription Drug User Fee Act" (PDUFA) target date by 3 months to December 15, 2021 Day .
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2021 Boehringer Ingelheim Prize selection announced
Time of Update: 2021-10-11
Weng Jianli from the School of Life Sciences received the 2021 Postdoctoral Award Boehringer Ingelheim will also appoint an in-company scientist as a joint mentor for the postdoctoral award winner to provide resources and scientific guidance for the subject .
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China-Israel Hyde: Going with "AI+Big Data", "Digital Intelligence Medical" explores the way to overcome hepatitis B
Time of Update: 2021-10-11
"Subversive" innovation opens up new pathsWhether it is to use AI technology to "start with the end" to improve the efficiency of drug research and development, or to create a personalized rehabilitation program for patients, the development path of China-Israel Hyde's "digital wisdom medical" is very different from that of traditional pharmaceutical companies, and is full of "subversive" Innovation factor .
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Fudan University mBio published a paper: Discovering new key genes for latent HIV infection
Time of Update: 2021-10-11
Zhu Huanzhang team AIDS is an infectious disease caused by human immunodeficiency virus (HIV) infection that seriously endangers people's lives and health .
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Concerned about rare diseases, Nestlé’s donation of Xiaobaitai can provide nutritional support for girls with intestinal Behcet's disease
Time of Update: 2021-10-11
Beijing, September 17, 2021/PRNewswire/ - On September 14, a special donation ceremony was held at the Red Cross Society of Jingxian County, Anhui Province - Nestlé Health Sciences provided an intestinal Behcet's disease in Jingxian County 'S girl donated "Xiaobai Taineng" special medical purpose all-nutrition formula food for nutritional treatment, and I wish her a speedy recovery .
