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A protein only a few nanometers in size acts as a molecular switch that plays a vital role in determining whether we feel hungry or full
Research exploring the "switch" nature of weight control is more important than ever
In their recently published research, the team led by Dr.
Drug treatments for pathological appetite increase still face the same challenges: "To date, all of these drug interventions have been plagued by side effects
As part of the current study, the researchers were able to clarify and visualize the 3D molecular structure of the hormone receptor MC4R (a member of the G-protein coupled receptor GPCR family)
Without cryo-electron microscopy and years of experience in protein production based on cell culture, it is impossible to have a basic basis for the nature of the smallest cell components
Dr.
The research team was able to show that how a previously known receptor inactivator - or antagonist - binds to the receptor is almost the same as the receptor activation agonist, with only one significant difference
Heyder N et al.
