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Liu Hongwei's group reveals a new mechanism for the intestinal fungus Candida parapsilosis to promote obesity
Time of Update: 2021-11-13
After further antifungal treatment of mice, oral gavage of Candida parapsilosis can promote the development of obesity induced by high-fat diet, which proves the causal relationship between the expansion of Candida parapsilosis and dietary obesity .
This study confirmed that the intestinal fungus Candida parapsilosis promotes the development of diet-induced obesity by producing lipase .
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Diversity of microorganisms is good for boys, but not for girls
Time of Update: 2021-11-13
Led by Juliette Madan and Margaret Karagas at Dartmouth College, the cohort study included longitudinal tracking of the developing microbiota from birth to understand its impact on the health and well-being of children .
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Nature Sub-Journal: Using Artificial Intelligence to Detect Colorectal Cancer
Time of Update: 2021-11-13
"But the final study showed that when we use artificial intelligence to diagnose colorectal cancer, in many cases, its performance is comparable to, or even better than, a real pathologist .
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A new target for the treatment of fatty liver
Time of Update: 2021-11-13
Brem Chair Professor of Medicine Neil Kaplowitz, MD, said: "In these experiments, we can prevent the entire progression by knocking out the SAB gene early in the liver of adult animals, and then feeding on a high-fat diet .
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Illumina supports Canada's nationwide COVID-19 genome sequencing project
Time of Update: 2021-11-13
November 3, 2021Data from 10,000 SARS-CoV-2 patients will be used to identify biomarkers that can help predict the potential risk of serious diseases and support the development of new therapies again
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Nature Concern: The first oral anti-coronavirus drug Molnupiravir
Time of Update: 2021-11-13
Image source: Merck & Co Inc Merck Pharmaceuticals announced in early October that the antiviral drug it is developing can halve the number of hospitalizations and deaths of COVID-19 patients .
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STTT Wei Wensheng's research team and collaborators report a new mechanism for the new coronavirus to activate the host's natural immune response
Time of Update: 2021-11-13
Nian 2021 11 Yue 3 days, Beijing University and the Chinese Academy of Medical Sciences Wei Wensheng research group / Beijing Union Medical College Wang Jianwei Task Force cooperation in Signal Transduction and Targeted Therapy magazine published an article entitled Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV The research paper of -2 infection reported a new mechanism for the new coronavirus to activate the host's natural immune response .
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Huante Biological Research Achievement Won the First Prize of Shennong China Agricultural Science and Technology Award
Time of Update: 2021-11-13
, the Institute of Agricultural Quality Standards and Testing Technology of the Chinese Academy of Agricultural Sciences, and the Zhejiang Academy of Agricultural Sciences - "Key technologies and applications for efficient identification and risk assessment of major hazards in agricultural products" was awarded The first prize of scientific research achievements of the Shennong China Agricultural Science and Technology Award in 2020-2021 .
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Argon Medical's innovative portal approach
Time of Update: 2021-11-13
, a global manufacturer of specialized equipment for interventional radiology, vascular surgery, and interventional cardiology, officially announced the launch of two unique sets of portal vein access devices , Used for the transjugular liver approach in diagnosis and interventional procedures .
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Drink alcohol to stay healthy? A new study suggests that this may not work
Time of Update: 2021-11-13
To a degree it is caused by other factors, including previous alcohol or drug problems, daily smoking and poor overall health .
04%) had one or more other risk factors for higher mortality, including previous alcohol use disorder or dangerous drinking (35.
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The Nobel Prize winner’s article shows how causal reasoning can understand biased police data
Time of Update: 2021-11-13
In his award-winning article, Knox explained the value of applying new tools and statistical techniques to imperfect data to reveal the extent and severity of racial prejudice among the police .
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"Nature Medicine" Obesity and hyperinsulinemia promote fat cells to activate cell cycle programs and aging
Time of Update: 2021-11-13
However, chronic hyperinsulinemia induced in vitro or in human diseases is associated with subsequent cell cycle exit, leading to premature aging of the transcriptome and secretion profile of adipocytes .
By proving that adipocytes can activate the cell cycle program, this is a mature mechanism of human adipocyte aging .
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The RNAi expression construct was introduced into the brain and found to be toxic
Time of Update: 2021-11-13
miS1 is safe in a short-term pilot study in non-human primates (NHP) .
By changing the miS1 expression environment, the activity of the ITR promoter is reduced .
Toxicity after AAV delivery of RNAi expression constructs into nonhuman primate brain.
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Physicists discover new quantum effects in double-layer graphene
Time of Update: 2021-11-13
Theorists at the University of Texas at Dallas and colleagues in Germany first observed a rare phenomenon in double-layer graphene called the quantum anomalous Hall effect .
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Moderna deploys "next generation in vivo gene editing therapy" program
Time of Update: 2021-11-13
The two parties did not disclose the specific details of the cooperation, but it is understood that Metagenomi has a large number of new gene editing nucleases, and Moderna has rich experience in the field of mRNA technology and delivery .
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Novartis will exhibit its latest COVID-19 detection products and solutions at MEDICA 2021
Time of Update: 2021-11-13
As one of the few domestic R&D and innovative enterprises with independent and controllable upstream technology development capabilities and terminal product production capabilities, Novartis has always adhered to the vision of using technology to improve human health, focusing on continuous investment in technological innovation and high-quality products .
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Mi Kaixia's group reveals the molecular mechanism of mycobacterial epigenetic regulation of isoniazid resistance
Time of Update: 2021-11-13
Based on the research results, we propose a new molecular mechanism for mycobacterial epigenetic regulation of isoniazid resistance--HsdM modifies the transcription level of genes through methylation modification, which changes the redox state of mycobacteria, thereby reducing tuberculosis bacteria Sensitivity to isoniazid (Figure 2) .
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Chinese scholars have made progress in the research of two-dimensional material synthesis methodology
Time of Update: 2021-11-13
However, non-van der Waals layered materials often have strong chemical bonds between layers, which greatly hinders the synthesis of their two-dimensional structure .
The new two-dimensional AgCrS2 nanosheets have obtained a composition and lattice structure similar to those of bulk materials .
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Bio-Techne announces that it has obtained GMP grade protein qualification certification from a dedicated GMP facility
Time of Update: 2021-11-13
For Bio-Techne and its new equipment, this means large-scale production of proteins with batch-to-batch consistency, providing GMP process capabilities for patient safety, and the scalability needed to support large-scale clinical trials and successful treatment in the future Sex .
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Empower robots with social skills
Time of Update: 2021-11-13
Researchers at the Massachusetts Institute of Technology have now incorporated certain social interactions into the framework of robots, enabling machines to understand what it means to help or hinder each other and learn to perform these social behaviors on their own .
