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    Home > Biochemistry News > Biotechnology News > A new target for the treatment of fatty liver

    A new target for the treatment of fatty liver

    • Last Update: 2021-11-13
    • Source: Internet
    • Author: User
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    Approximately 80 million Americans suffer from fatty liver that has nothing to do with alcoholism


    Due to the complexity of the disease, low efficacy or toxicity of the drug, some drugs in the late stage of development have failed


    In order to understand the complexity of fatty liver disease progression, a group of scientists from the University of Southern California explored the molecular mechanism of experimental NAFL/NASH


    SAB is the outer membrane protein of mitochondria, and mitochondria are called the power source of cells


    Keck Professor of Medicine and Thomas H.


    The study was recently published in the American Association for The Study of Liver Diseases' Hepatology


    These rats were fed—actually overfed—high-fat food pellets, supplemented with sucrose and fructose water


    One advantage, Win said, is, “We don’t need to completely delete or knock out the SAB protein


    This study shows that the damage to the liver caused by dietary choices can be avoided through moderate behavioral changes


    Kaplowitz said: "There is no doubt that many methods that have been successful in mice are not effective in humans



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