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The RNAi expression construct was introduced into the brain and found to be toxic

 Last Update: 2021-11-13
 Source: Internet
 Author: User

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medicine drug

type 1 ifn

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RNA interference (RNAi) targeting spinocerebellar ataxia type 1 can prevent and reverse behavioral defects and neuropathological readings in mouse models, and its safety and benefits can last for several months

But after transporting AAV.

Toxicity after AAV delivery of RNAi expression constructs into nonhuman primate brain.

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