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Liu Hongwei's group reveals a new mechanism for the intestinal fungus Candida parapsilosis to promote obesity

 Last Update: 2021-11-13
 Source: Internet
 Author: User

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The research group added three antifungal drugs with different antibacterial spectrums to the drinking water of mice fed with high-fat feed: Amphotericin B (covering Candida and Aspergillus), fluconazole (Candida and Cryptococcus) and Flucytosine (poor activity against Candida and Cryptococcus) was used to observe the effect of intestinal fungi on obesity in mice

How does Candida parapsilosis promote obesity?

Lipase in the intestine can promote fat accumulation in the human body by converting dietary triglycerides into monoglycerides and free fatty acids, which is the target of the weight-loss drug orlistat

This study confirmed that the intestinal fungus Candida parapsilosis promotes the development of diet-induced obesity by producing lipase

Link to the paper: https://

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