-
Surprisingly, these microRNAs promoted, rather than inhibited, the expression of proteins
Time of Update: 2023-01-06
High-Throughput Analysis Reveals miRNA Upregulating a-2,6 Sialic Acid Through Direct miRNA: miRNA Interactions MicroRNAs play a role in cancer development and are thought to only inhibit protein expression in dividing cells, such as tumor cells.
-
Guangzhou Health Center has made progress in the research of antibody immune response in the new coronavirus escaping population
Time of Update: 2023-01-06
The study found a human neutralizing antibody R1-32 that targets the viral protein receptor binding domain (RBD) semi-hidden epitope and has a high affinity, mainly Prevents the virus from entering the cell by breaking open the spike protein and disintegrating it; Analysis of the antibody panel library showed that R1-32-like antibodies encoded by IGHV1-69 were widely induced in people infected with the new crown.
-
MINQI WANG'S LAB PUBLISHED PAPERS IN FERMENTATION-BASEL
Time of Update: 2023-01-06
3390/fermentation8100531Published: OCT 2022Document type: ArticleAttachment: Full text link ：Production of Butyric Acid from Hydrolysate of Rice Husk Treated by Alkali and Enzymes in Immobilized Fermentation by Clostridium tyrobutyricum Ct Delta pta（ IF=5.
-
Personalized genome sequencing doubles the rate of diagnosis of rare diseases
Time of Update: 2023-01-06
1038/s41467-022-32908-7 Researchers at University College London (UCL) recently published an article in the journal Nature Communications that tailoring whole genome sequencing analysis to individual patients can double the diagnostic rate of rare diseases.
-
Personalized genome sequencing doubles the rate of diagnosis of rare diseases
Time of Update: 2023-01-06
1038/s41467-022-32908-7 Researchers at University College London (UCL) recently published an article in the journal Nature Communications that tailoring whole genome sequencing analysis to individual patients can double the diagnostic rate of rare diseases.
-
The Vpu protein of the HIV virus makes it harder for antibodies to recognize infected cells
Time of Update: 2023-01-06
More specifically, they found that restoring Vpu expression greatly reduced the infected cells' ability to recognize nnAbs, making them resistant to ADCCs. In addition, they write, "The use of nnAbs in humanized mice only lowered the viral load of animals infected with Vpu-deficient virus, not wild-type viruses.
-
Nature Zhang Ning/Zhang Zemin/Zhu Jiye collaborated to reveal liver cancer immune microenvironment subtypes and neutrophil heterogeneity
Time of Update: 2023-01-06
The heterogeneity of the immune microenvironment is one of the important reasons for tumor resistance, recurrence and poor prognosis. In recent years, immunotherapy and combination therapy have broug
-
A novel adamantane-type PPAP pain relief molecule with significant Cav3.2 T-type calcium channel inhibition
Time of Update: 2023-01-06
8;font-family:;font-size:12pt;}Polycyclic polyprenylated acylphloroglucinol (PPAP) is a class of natural products with heterozygotic pathways, mainly including bridge ring type, adamantane type and further cracking ring due to the above two architecture types, Rearrangement and sidechain looping of its precursors results in a variety of structurally diverse derivative structure types.
-
Eating seafood raw can be poisoned: the "highway" of cells is diverted
Time of Update: 2023-01-06
Pointed-end processive elongation of actin filaments by Vibrio effectors VopF and VopL A new study has found that a toxin released by a bacterium that causes diarrheal disease hijacks cellular processes, forcing important proteins to assemble into "nowhere to go," diverting proteins from other jobs that are essential for the cell's normal function.
-
Eating seafood raw can be poisoned: the "highway" of cells is diverted
Time of Update: 2023-01-06
Pointed-end processive elongation of actin filaments by Vibrio effectors VopF and VopL A new study has found that a toxin released by a bacterium that causes diarrheal disease hijacks cellular processes, forcing important proteins to assemble into "nowhere to go," diverting proteins from other jobs that are essential for the cell's normal function.
-
New biomarkers for early diagnosis of Alzheimer's disease
Time of Update: 2023-01-06
Using postmortem brain tissue from AD patients and non-AD subjects, the researchers identified several p-tau biomarkers associated with selectivity for tau protein aggregation.
Using postmortem brain tissue from AD patients and non-AD subjects, the researchers identified several p-tau biomarkers associated with selectivity for tau protein aggregation.
-
New biomarkers for early diagnosis of Alzheimer's disease
Time of Update: 2023-01-06
Using postmortem brain tissue from AD patients and non-AD subjects, the researchers identified several p-tau biomarkers associated with selectivity for tau protein aggregation.
Using postmortem brain tissue from AD patients and non-AD subjects, the researchers identified several p-tau biomarkers associated with selectivity for tau protein aggregation.
-
PNAS: Revolutionary mammalian gene drive technology
Time of Update: 2023-01-06
Proceedings of the National Academy of Sciences, 2022; 119 (46) Researchers at the University of Adelaide have published their first findings on the potential effectiveness of revolutionary gene drive technology in controlling invading mice.
-
PNAS: Revolutionary mammalian gene drive technology
Time of Update: 2023-01-06
Proceedings of the National Academy of Sciences, 2022; 119 (46) Researchers at the University of Adelaide have published their first findings on the potential effectiveness of revolutionary gene drive technology in controlling invading mice.
-
SNAP benefits can help you improve your memory
Time of Update: 2023-01-06
Senior author Dr. Adina Zeki Al Hazzouri, assistant professor of epidemiology at Columbia University's Melman School of Public Health, said: "Less than half of older adults who are eligible for the SNAP program actually participated in this study, but our findings suggest that over a 10-year period, people who used the SNAP program experienced two years less cognitive aging than those who did not.
-
Luo Huan and Zhang Hang's research group published a paper in Progress in Neurobiology to reveal the dynamic emergence of relationship network structure in the human brain, as well as its neural mechanism and computer theory
Time of Update: 2023-01-06
In summary, Luo Huan and Zhang Hang's research group combined behavioral, neural and computational models to reveal the neural mechanism and computer theory behind the human brain's extraction and learning from continuous picture streams, and then establishing the neural mechanism and computer theory of high-order statistical structure (intracluster compression and intercluster distance) from this low-order transfer probability.
-
PNAS Announces Revolutionary Gene Drive Technology: The First Results in Controlling Invasive Mice
Time of Update: 2023-01-06
"Leveraging a natural murine meiotic drive to suppress invasive populations Researchers at the University of Adelaide have published their first findings on the potential effectiveness of revolutionary gene drive technology in controlling invading mice.
-
Researchers have discovered a new oral drug that lowers cholesterol
Time of Update: 2023-01-06
In the new study, Stamler and his colleagues show that nitric oxide can also target and inhibit PCSK9, thereby lowering cholesterol.
In the new study, Stamler and his colleagues show that nitric oxide can also target and inhibit PCSK9, thereby lowering cholesterol.
-
THE LEMIN LAB PUBLISHES PAPERS IN MICROBIOLOGY SPECTRUM
Time of Update: 2023-01-06
02479-22Published online: OCT 2022Document type: Article; Early AccessAttachment: Full text link ：Comprehensive Assessment of Subtyping Methods for Improved Surveillance of Foodborne Salmonella（IF=8.
02479-22Published online: OCT 2022Document type: Article; Early AccessAttachment: Full text link ：Comprehensive Assessment of Subtyping Methods for Improved Surveillance of Foodborne Salmonella（IF=8.
-
Trust in experts, media literacy and COVID-19 vaccine willingness are correlated
Time of Update: 2023-01-06
One survey found that respondents' willingness to receive COVID-19 vaccines had more to do with their media literacy and perceptions of health experts than with virus knowledge or previous vaccination behaviors.
