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Protollin Alzheimer's Disease Preventive Vaccine for Nasal Use Starts Trial
Time of Update: 2022-01-01
At the end of July this year, Tianjing Biotechnology announced that Protollin, a new drug under development for the treatment of Alzheimer's disease, was approved by the FDA to initiate a phase 1 clinical trial .
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Reindeer Medical and Cinda Bio will report the latest research results of BCMA CAR-T (CT103A) at the 2021 ASH annual meeting
Time of Update: 2022-01-01
Nanjing, Shanghai and San Francisco, November 10, 2021 /PRNewswire/ - Reindeer Medical, an innovative biopharmaceutical company in the clinical stage dedicated to the development and industrialization
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Genetron Health's two new research results in cancer are unveiled at the 2021 American Society for Molecular Pathology Annual Meeting (AMP 2021)
Time of Update: 2022-01-01
Beijing, November 16, 2021/PRNewswire/ - Recently, at the 2021 online annual meeting (AMP 2021) held by the American Society of Molecular Pathology, Genetron Health (NASDAQ: GTH) released two Seq-based -The latest research results of MRD® and FusionScan Plus products (Abstract No.
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Turnstone Biologics reached a partnership to develop tumor infiltrating lymphocyte therapy
Time of Update: 2022-01-01
This collaboration will focus on using Turnstone's next-generation TIL manufacturing strategy, developing innovative candidate therapies for the treatment of multiple solid tumor types, and supporting the company's IND application for the company's main TIL project TIDAL-01 .
Reference materials:[1] Turnstone Biologics Announces Research Collaboration with Moffitt Cancer Center to Advance Novel TIL Immunotherapies for Solid Tumor Indications.
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Nature reveals for the first time the mechanism of herpes virus invading the nervous system
Time of Update: 2022-01-01
Smith and his research team discovered that the herpes virus uses the kinesin engine it brings from other cells to transport it to the nucleus of neurons .
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New immune checkpoint for pancreatic cancer discovered
Time of Update: 2022-01-01
" Recently, Lu Chunwan's research team from the School of Life Sciences of Tianjin University and the Georgia Medical College team revealed the molecular mechanism of pancreatic cancer immune escape and resistance to immune checkpoint blocking therapy, and discovered a new type of immunity in the pancreatic tumor microenvironment Checkpoint .
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Haisco's "Cycloprofen" New Indications Reported on the Market
Time of Update: 2022-01-01
According to the Insight database, Haisco has currently initiated 6 phase 3 clinical trials for cycloporol, 5 of which have been completed, which most likely corresponds to the 5 indications declared by it .
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Release of vaccine development strategy for Omicron's new crown variant Moderna
Time of Update: 2022-01-01
Moderna is testing the serum of high-dose booster vaccinators to determine whether this dose can provide a higher neutralizing ability for Omicron .
The historical experience of developing new crown vaccines for Beta and Delta variants in 2021 shows that the company has the ability to advance new vaccine candidates to clinical trials within 60-90 days .
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Scientists have discovered new forces behind mass extinctions in the past
Time of Update: 2022-01-01
Figure: Copper-rich minerals indicate extensive volcanic activity during the end of the Permian mass extinction in different areas of southern China (A: Taoshujing area; B: Lubei area; C: Guanbachong; D: Taoshujing locality; Ai Fan :Longmendong location) .
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Why is "Cancer King" so aggressive
Time of Update: 2022-01-01
The researchers said that although the discovery is only preliminary, it opens up promising new treatment avenues for pancreatic cancer, an extremely aggressive cancer, and clarifies its metastasis mechanism .
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mRNA expression triple immunoregulatory factor Moderna immunotherapy shows preliminary anti-cancer activity
Time of Update: 2022-01-01
A few days ago, Moderna announced the preliminary phase 1 clinical trial results of its mRNA immunotherapy mRNA-2752 for the treatment of solid tumors and lymphoma patients .
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Bacteria may be the key technology for sustainable extraction of earth elements
Time of Update: 2022-01-01
A new study describes a principle that proves that engineered bacteria, Gluconobacter gluconate, requires a big first step to meet the skyrocketing demand for rare earth elements in a way that matches the cost and efficiency of traditional thermochemical extraction and refinement.
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Not affected by mutant strains!
Time of Update: 2022-01-01
▲The effect of the new crown mutant strain on vaccine peptides (picture source: reference [1])Therefore, this test showed good safety and induced a T cell immune response .
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New drugs may be able to prevent cancer metastasis by promoting cancer cells to enter dormancy
Time of Update: 2022-01-01
Recently, in a research report titled "An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy" published in the International Journal of Experimental Medicine, scientists from the Icahn School of Medicine at Mount Sinai found that one A new type of therapeutic approach may prevent the growth of metastatic tumors by promoting cancer cells to enter a dormant state where they cannot proliferate .
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Vaccines can be vaccinated by cupping. Scientists use ancient methods and modern methods to increase delivery efficiency by nearly 100 times
Time of Update: 2022-01-01
GFP expression under dermal aspirationThen the researchers used a single variable method to study the dependence of pressure, treatment time, DNA amount and device type on GFP expression.
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New progress has been made in the second-generation new crown vaccine!
Time of Update: 2022-01-01
Professor Zhu Fengcai said that after receiving two doses of 20μg of ReCOV vaccine, the neutralizing antibody level data exceeded expectations.
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What is the difference between OS, PFS and DFS?
Time of Update: 2022-01-01
Progression-free survivalProgression-free survivalprogression-free survival, PFSprogression-free survival, PFSDefined as: the time from the start of randomization to the progression of tumors (in any aspect) or death (for any reason) .
Therefore, in the design of clinical trials, the criteria for "tumor progression" must be clearly defined, including PFS assessment, observation, and analysis methods.
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Three registration review guidelines are issued involving clinical trials of diagnostic reagents, surgical instruments, etc.
Time of Update: 2021-12-31
95 of 2021)In order to strengthen the supervision and guidance of medical device product registration, and further improve the quality of registration review, the National Medical Products Administration has organized and formulated the "Guidelines for the Registration and Review of Non-original Companion Diagnostic Reagents for Anti-tumor Drugs" and "Using In Vitro Diagnostic Reagents for Overseas Clinical Trials" Guiding Principles for Registration and Review of Trial Data are hereby released .
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The Aquatic Institute has made new progress in the technology of controlling algae blooms in reservoirs based on precise water level regulation
Time of Update: 2021-12-31
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PNAS: There is still a big gap in the exploration of animal genome sequencing
Time of Update: 2021-12-31
-According to an analysis led by Washington State University, efforts to sequence the world’s animal genomes tend to focus on those animals that resemble humans most, and this work is done almost entirely in the north of the world .
