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Hostility in cells takes over: pathogens hijack host mitochondria
Time of Update: 2022-01-21
Because the outer membrane of these organelles is the first point of contact with the pathogen, we looked at it more closely," Lena Penas, research group leader at the Max Planck Institute for the Biology of Aging, explains .
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In Down syndrome cells, genome-wide disruption mimics an aging-like state
Time of Update: 2022-01-21
Source: David Orenstein/Picall InstituteThe study found that neural progenitor cells (NPCs), which develop into the main cells in the brain including neurons, are markedly characterized by aging, said Li-Huei Cai, senior author of the novel, but it was confirmed by the team's extensive work to elucidate the underlying mechanisms The effect of abnormal chromosome number, or aneuploidy, in the nucleus .
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Scientists discover 'drug resistance gene' in deadly E. coli
Time of Update: 2022-01-21
Professor Mark Schembri, from the University of Queensland's School of Chemistry and Molecular Biosciences, said the "resistance gene" was spreading incredibly fast .
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Chinese scholars have made progress in the synthesis of lignin-based thermoplastic elastomers
Time of Update: 2022-01-21
Professor Zhang Yuetao's team used Lewis superbase containing bifunctional groups as initiators to initiate polymerization at both ends at the same time, and skillfully combined the polymerization kinetics of Lewis acid-base pairs with Lewis base dual initiators to successfully realize lignin-based One-step synthesis of high-performance all (meth)acrylate triblock thermoplastic elastomers .
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Chinese scholars and overseas collaborators have made new progress in the synthesis of new ultra-large pore molecular sieves
Time of Update: 2022-01-21
Camblor from the Madrid Institute of Materials Research, Li Jian from Peking University/Stockholm University, and China University of Petroleum (East China) With the cooperation of Chen Xiaobo and other teams, new progress has been made in the synthesis of new ultra-large pore molecular sieves .
Recently, the above-mentioned team reported the stable aluminosilicate zeolite ZEO-1 with multi-dimensional ultra-large pore structure .
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A nationwide survey by the team of researcher Liu Jue of the School of Public Health shows that more than 90% of the research subjects are willing to receive a booster shot of the new crown vaccine
Time of Update: 2022-01-21
The results of the National Survey on China's New Crown Vaccine Booster Inoculation Willingness and Its Related Factors by the research team of Liu Jue from the School of Public Health of Peking University showed that more than 93.
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Can your sweat tell you about your health?
Time of Update: 2022-01-21
"While there are a growing number of low-cost wearable sensors that can collect and analyze sweat to assess a person's health, Kim's 3D printed models integrate mechanically flexible electrochemical sensors and wireless communication capabilities .
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Chinese scholars and overseas collaborators have made new progress in celestial radiation
Time of Update: 2022-01-21
After long-term observations of the accreting neutron star "Scorpius X-1", Professor Feng Hua's team detected a significant polarization signal using aurora, and put forward strict restrictions on the location and geometry of the radiation region, indicating that the second type of competition model is correct physical explanation .
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Chinese scholars have made progress in organocatalytic synthesis of carbon dioxide-based polycarbonate
Time of Update: 2022-01-21
This study enriches the organic catalytic system of CO2 and epoxy copolymerization, especially the synthesis of CO2-based polycarbonate under normal temperature and pressure conditions, which provides a new idea for the efficient conversion of CO2 .
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A deadly combination: discovering a new direct cause of cell death
Time of Update: 2022-01-21
It is well known that the so-called "apoptosis-enforcing protein" BAX encounters DRP1 on the mitochondrial membrane of cells .
"It's impressive that cells start to die only by forcing the interaction between BAX and DRP1 without another death trigger," Garcia-Seth said .
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"JAMA" sub-issue: drinking coffee can reduce colorectal cancer deaths and prolong survival
Time of Update: 2022-01-21
And among those with metastatic colorectal cancer, those who drank 2-3 cups of coffee a day had longer overall survival and a lower risk of cancer progression, while those who drank 4 cups of coffee a day had a greater benefit .
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An oolong?
Time of Update: 2022-01-21
Dr. Ramesh Shivdasani, Dana-Farber Cancer InstituteThe disease was long thought to be the result of cells in the esophagus turning into cells of the gut, but researchers have discovered that the d
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Discovery in Nature may hold key to alleviating metabolic disease
Time of Update: 2022-01-21
Familial partial lipodystrophy type 2 (FPLD2) is a rare disorder that causes diabetes, loss of fat in the extremities, and excessive muscle development, but the defective protein (lamin a) is present in all cells .
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Nature discovers a group of cellular receptors
Time of Update: 2022-01-21
Jonathan Abraham, the study's senior author, said that understanding the basic biology of the viral life cycle is critical to finding ways to prevent disease, and building such basic knowledge before an outbreak is critical to preparing for future outbreaks .
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Take off the reading glasses once a day!
Time of Update: 2022-01-12
The test results showed that the two formulations of Brimochol and the active control drug group reached the primary endpoint of improving near vision in patients with presbyopia without significant loss of distance vision.
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The latest international research and development of microbial ink: printable 3D materials can isolate toxic chemicals
Time of Update: 2022-01-12
China News Service, Beijing, November 24 (Reporter Sun Zifa) Springer Nature’s academic journal "Nature-Communications" recently published a proof-of-concept biotechnology research paper saying that researchers have developed a microbial ink that can Used to print 3D materials with functional and programmable properties .
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Phase IIb clinical results of antisense oligonucleotide therapy positively significantly reduce blood lipid levels
Time of Update: 2022-01-12
The results showed that compared with placebo, at week 24, subjects in all dose groups of vupanorsen achieved a statistically significant reduction in non-HDL-C levels, reaching the primary endpoint .
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Breast diseases are caused by breath?
Time of Update: 2022-01-12
It can be seen that part of the symptoms of breast pain are related to mood changes .
However, diseases such as breast cancer or benign tumors in the breast have little to do with daily mood changes .
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PD-1/PD-L1 combination therapy is fully combed: 119 studies and 65 programs 8% are approved for marketing
Time of Update: 2022-01-12
The researchers systematically searched the Phase II trials of PD-1/PD-L1 inhibitors combined with other anticancer therapies published between January 1, 2018 and December 31, 2020, and 119 articles were included in the final analysis .
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How to design targeted protein degradation agents more effectively?
Time of Update: 2022-01-12
In in vitro experiments, it showed stronger anti-leukemia activity compared with PROTAC molecules that only target the degradation of BCL-xL .
