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Hostility in cells takes over: pathogens hijack host mitochondria

 Last Update: 2022-01-21
 Source: Internet
 Author: User

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In order to survive, pathogens need to obtain nutrients from and resist the host's defenses

Mitochondria shed 'skin'

The researchers infected cells with the human parasite Toxoplasma gondii and observed what was happening in the outer cavity of mitochondria in vivo under a microscope

hostile takeover

But how does the parasite acquire mitochondria? The team found that the pathogen has a protein that functionally mimics the host mitochondrial protein

Lena Pernas is also head of the Excellence Group for Ageing Research at CECAD Cologne University

Journal Reference :

Xianhe Li, Julian Straub, Tânia Catarina Medeiros, Chahat Mehra, Fabian den Brave, Esra Peker, Ilian Atanassov, Katharina Stillger, Jonas Benjamin Michaelis, Emma Burbridge, Colin Adrain, Christian Münch, Jan Riemer, Thomas Becker, Lena F.

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