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Demographers calculate: China's population may start to shrink this year
Time of Update: 2022-02-22
<></> After decades of growth, China's population may begin to shrink this year, data released yesterday by China's National Bureau of Statistics showed .
Based on this figure, demographers estimate that China's total fertility rate (the number of children a person will have in a lifetime) fell to around 1.
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Researchers discover new way to determine effectiveness of cancer treatments
Time of Update: 2022-02-22
In this study, the researchers found that compared with ambient air, the susceptibility of primary cancer cells to anticancer drugs was Tumors collected, processed, and propagated in O2 displayed distinct differences in key signaling networks, including LGR5/WNT, YAP and NRF2/KEAP1, nuclear reactive oxygen species, alternative splicing, and sensitivity to targeted therapy .
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Nature sub-journal identifies new mechanism to protect DNA
Time of Update: 2022-02-22
The researchers found that this new function involves the activity of a new form of 53BP1, in which the protein aggregates and forms small droplets in regions of condensed DNA -- a process known as liquid-liquid phase separation, similar to that found in salad dressings.
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The Gao Xin team of Suzhou Institute of Medical Technology developed an automatic vertebral fracture AI imaging workstation
Time of Update: 2022-02-22
Tested by a third-party testing agency (see Figure 2 ), the workstation's diagnostic accuracy rate reached 0.
The AI imaging workstation for vertebral fractures established in this project does not require any forensic intervention.
Workflow of the AI imaging workstation for vertebral fractures Figure 2.
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'Off-target' metabolic effects of anti-inflammatory drugs for autoimmune diseases
Time of Update: 2022-02-22
"In this study, published in the Journal of Clinical Investigation, researchers conducted a literature review of more than 200 studies to assess and interpret what is known about target/irrelevant (adverse) effects and the effects of current AIRD therapy on the Mechanisms of action in lipid metabolism, immune cell function and cardiovascular disease risk .
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Self-assembling peptides (JigSAP) solve the challenge of tissue regeneration
Time of Update: 2022-02-22
In a study published this month in the journal Nature Communications, a research team at Tokyo Medical and Dental University (TMDU) developed a serrated peptide that executes the extracellular matrix (ECM) The basic function of ECM as an artificial ECM for regeneration of injured tissue .
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Neuron: New AI model helps uncover causes of motor neuron disease
Time of Update: 2022-02-22
The machine learning tool, called RefMap, was designed by researchers at the University of Sheffield and Stanford University School of Medicine, and the team has used it to identify 690 risk factors for motor neuron disease.
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Chinese scholars and overseas collaborators have made progress in electrocatalytic hydrogen evolution research
Time of Update: 2022-02-22
21773146, 22003036, 22102092), Professor Cao Rui's team from Shaanxi Normal University cooperated with overseas scholars to use intramolecular crown ether groups to build water clusters around the cobalt corrole catalytic center The hydrogen bond network assists proton transfer and significantly promotes the electrocatalytic hydrogen evolution reaction .
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Infection with COVID-19 during pregnancy may cause fetal inflammation even without placental infection
Time of Update: 2022-02-22
The report, Maternal-Fetal Immune Response in Pregnant Women Infected with SARS-CoV-2, published today in the journal Nature Communications , reports that COVID-19 infection during pregnancy may lead to an inflammatory immune response in the fetus, even if the virus does not infect the placenta .
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Tongji University developed an autonomous intelligent needle-free vaccine injection robot
Time of Update: 2022-02-22
After obtaining the spatial pose information of the vaccine injection site, an adaptive robotic arm is used in this project to hold the needle-free syringe near the injection site, and a precise force control algorithm is applied to ensure that the syringe closely fits the human skin and is in contact with the surface of the human skin.
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Chinese scholars elucidate the obesity paradox, the treatment of "heart power" should follow the circadian rhythm
Time of Update: 2022-02-22
“During the resting phase, which is at night in humans and during the day in mice, the heart uses fatty acids released from fat as its primary energy source .
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Two COVID-19 vaccines from AstraZeneca and Johnson & Johnson pose a risk of transverse myelitis
Time of Update: 2022-02-22
In addition, the PRAC noted that a small number of thrombosis with thrombocytopenia (TTS) cases were reported following the second dose of AstraZeneca's COVID-19 vaccine Vaxzevria .
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Scientists discover 'resistance gene' in deadly E. coli
Time of Update: 2022-02-22
The research, led by the University of Queensland, has uncovered a particular form of the bacterium, Escherichia coli ST131, which has a previously unnoticed gene that makes it highly resistant to commonly used antibiotics .
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How Zika evades cellular antiviral responses
Time of Update: 2022-02-22
The Northwestern University paper describes how Zika evades detection by host cells by targeting STAT2, a mediator of the cellular antiviral immune response, through a protein called NS5 .
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PNAS: The secret to compressing DNA to a millionth size
Time of Update: 2022-02-22
The arrangement mechanism that condenses chromosomes into millionths of size without any tangle, and the 3D structures that achieve this, has puzzled researchers for more than half a century .
Professor Changyong Song explained: "Using coherent X-rays from synchrotrons, the three-dimensional structure of chromosomes has been determined through high-resolution images at the nanoscale .
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Chinese scholars have made progress in the genetic mechanism of obsessive-compulsive disorder
Time of Update: 2022-02-22
81971292, 82071518), researcher Lin Guanning of Shanghai Jiaotong University and chief physician Wang Zhen of Shanghai Mental Health Center cooperated to analyze the ultra-rare obessive-compulsive disorder at the genome-wide level , OCD) mutation, and new progress has been made in the study of the etiology of obsessive-compulsive disorder .
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New MRI technique could improve diagnosis and treatment of multiple sclerosis
Time of Update: 2022-02-22
Looking to the future, Wolfgang Bergner said: "If the results are confirmed in further studies, this new neuroimaging technique could become a standard imaging tool for initial diagnosis, monitoring disease activity and treating patients with multiple sclerosis .
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Imidazolyl-based zwitterionic polymers for dual antiviral and antibacterial functions
Time of Update: 2022-02-22
SummaryTo reduce the serious health risks and enormous economic impact posed by the spread of SARS-CoV-2, an imidazolyl-based zwitterionic polymer was designed, synthesized, and demonstrated to achieve contact loss of human coronaviruses under dry ambient conditions.
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Comprehensive control of Pseudomonas metabolic state by modulating the polyhydroxyalkanoate cycle
Time of Update: 2022-02-22
The simultaneous synthesis and degradation of PHA drives a dynamic cycle associated with central carbon metabolism that regulates a number of diverse bacterial processes such as stress tolerance, pathogenesis, and persistence .
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Chinese scholars have made progress in the field of organic solar cells
Time of Update: 2022-02-22
At the same time, Professor Tayebeh Ameri of the University of Edinburgh, UK, in the News and Views column of "Nature Energy", with "Going green at large" (link: https:// com/articles/s41560-021-00936-0), made a positive comment on the significance and results of this research work: the guest-assisted assembly strategy facilitates the preparation of efficient and stable organic photovoltaic modules with environmentally friendly solvents, and solves the problem of organic photovoltaic modules.
