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A woman appears to be cured of HIV after umbilical cord transplant
Time of Update: 2022-03-05
However, these transplants are unlikely to benefit AIDS patients who do not have other diseases such as cancer, AIDS researcher Sharon Lewin (director of the Peter Doherty Institute for Infection and Immunity in Melbourne, Australia, who was not involved in the work) told The Wall Street Journal.
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Sperm or egg?
Time of Update: 2022-03-05
Image: Various species of the genus Macrostomum: This planarian is transparent and allows the size of male and female reproductive organs in live animals to be determined under a microscope .
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A cholera vaccine that may be more durable
Time of Update: 2022-03-05
Image: A virus-like particle (Qβ-OSP conjugate) showing that Vibrio cholerae polysaccharide produces a strong, long-lasting immune response in mice .
The immune system produces antibodies against the surface o-specific polysaccharide (OSP) of Vibrio cholerae, but this polysaccharide alone does not generate a strong, long-lasting immune response .
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AJHG: Exome sequencing improves diagnosis and treatment of male infertility
Time of Update: 2022-03-05
Coincidentally, for these 12 patients with meiosis-related gene mutations, their testicular sperm retrieval treatment also failed .
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"Cell" Gut fungi affect neuroimmunity and behavior
Time of Update: 2022-03-05
"We have established a direct link between major immune pathways induced by fungi in the gut lining and nervous system signals that influence animal behavior," said senior author Iliyan Iliev, PhD, medical immunology in gastroenterology and hepatology Associate Professor and member of the Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine .
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PNAS: Novel nanoparticles target gene therapy directly to the lungs
Time of Update: 2022-03-05
Even before LNP delivery made its splashy debut with a COVID-19 vaccine, Qiaobing Xu and his team are applying the technology to a wider range of diseases with treatments that target specific tissues and organs, which could help reduce the risk of infection in other healthy parts of the body.
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Stem cell infusion improves survival in mice with sepsis
Time of Update: 2022-03-05
The team suspects that the decline in the number of cells in HSPCs is because these cells work overtime to produce the immune and blood cells needed to fight infection and severe inflammation caused by sepsis .
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You Fuping's team reveals a new mechanism of innate immune signaling regulating m6A modification
Time of Update: 2022-03-05
On February 15, 2022, You Fuping's team from Peking University School of Basic Medicine published a research paper titled " TBK1-METTL3 axis facilitates antiviral immunity " in Cell Reports , reporting that TBK1, a key kinase in the innate immune signaling pathway, can be used in virus Directly interacts with METTL3 after infection and enhances the body's type 1 interferon response through dual regulation of METTL3 function .
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Immunogenetic studies of diverse populations are critical
Time of Update: 2022-03-05
Along with Blandina T Mmbaga, director of the Kilimanjaro Clinical Research Institute in Tanzania, and her colleagues Godfrey Temba and Vesla Kullaya, Boahen investigated how these responses occurred in healthy Tanzanian adults of East African ancestry .
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UCI team uncovers key brain mechanism for timely organization of memories
Time of Update: 2022-03-05
Combining electrophysiological recording techniques in rodents with statistical machine-learning analysis of large amounts of data, UCI researchers found evidence of advances in hippocampal networks encoding and preserving experience to aid decision-making .
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New study identifies genes most likely to cause heart attack
Time of Update: 2022-03-05
Executive Director of the Victor Chang Heart Institute, Professor Jason Kovacic, lead author of the paper, said the study achieved three major breakthroughs, all of which are critical in the fight against heart disease .
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Pervasive regulation of RNA metabolism enhances root colonization of nitrogen-fixing symbiotic α-rhizobia
Time of Update: 2022-03-05
Here, we decipher a post-transcriptional network regulated by homologous genestrans- Small RNAs (sRNAs) AbcR1 and AbcR2, metabolism of recombinant nitrogen-fixing alpha rhizobiumPhytophthora rhizobiumSymbiosis with the legume host alfalfa in the pre-infestation stage .
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When a protective gene buffers a bad gene, the heart can beat
Time of Update: 2022-03-05
Whole-genome sequencing revealed that they all carried an extremely rare genetic mutation called TPM1, which was absent in more than 900 unrelated samples from patients with congenital heart disease and, worldwide, only Appeared twice .
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Forgotten species will go extinct twice
Time of Update: 2022-03-05
Dr Diogo Verissimo, a researcher in the Department of Zoology at the University of Oxford and co-author of the study, said:"Social extinction occurs not only in species that have gone extinct, but also in those that still live around us, often due to social or cultural changes, such as urbanization or digitization of society, that fundamentally alter us relationship with nature and lead to the loss of collective memory .
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Computational modelling experts pioneer pest eradication model
Time of Update: 2022-03-05
A new study, published in the journal Scientific Reports, establishes an Individual-Based Modeling (IBM) technique to explain and predict the formation of high slug density patches in cultivated land .
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Science Sub-Journal: Making "Universal Blood Type" Organs
Time of Update: 2022-03-05
Patients with blood type O who need a lung transplant have a 20% higher risk of dying while waiting for a matching organ to arrive," said Dr Aizhou Wang .
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Cai Yingfan's team published a paper in Plant Physiology to reveal the mechanism of lncRNAs regulating cotton's resistance to Verticillium wilt
Time of Update: 2022-03-05
MsoNormal{ mso-> On February 15, 2022, Professor Cai Yingfan's team from the School of Life Sciences published a research paper on " lncRNA7 and lncRNA2 modulate cell wall defense genes to regulate cotton resistance to Verticillium wilt" in Plant Physiology , revealing that cotton long non-coding RNAs are encoded by Molecular mechanisms by which small peptides and auxin pathways regulate cell wall defense-related genes and thus regulate cotton Verticillium wilt resistance .
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The "platypus" of the crab world
Time of Update: 2022-03-05
Researchers initially thought Callichimaera was a species of giant-eyed crab, and in the final larval stage, the young crabs are free-swimming predators when their eyes are relatively large .
The researchers next plan to study the biomechanics of Callichimaera swimming, Luke said .
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Cell Reports Reveals Novel Mechanism of Innate Immune Signals Regulating m6A Modification
Time of Update: 2022-03-04
On February 15, 2022, You Fuping's team from Peking University School of Basic Medicine published a research paper titled "TBK1-METTL3 axis facilitates antiviral immunity" in Cell Reports, reporting that TBK1, a key kinase in the innate immune signaling pathway, can act in virus Directly interacts with METTL3 after infection and enhances the body's type 1 interferon response through dual regulation of METTL3 function .
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Oral microbiota interacts with bone cells by influencing immune cells
Time of Update: 2022-03-04
The findings showed that healthy microbes in the mouth activated a group of immune cells in the alveolar bone marrow, which in turn boosted osteoclasts responsible for destroying bone .
