-
Opdivo+Yervoy is similar to Keytruda+Inlyta!
Time of Update: 2022-04-30
According to the results of a study presented recently at the 2022 American Society of Clinical Oncology Genitourinary Cancer Symposium (ASCO GU), the "dual immunization" regimen Opdivo (nivolumab, nivolumab) + Yervoy (ipilimumab, ipilimumab) Muma) and the "immune + targeting" regimen Keytruda (pembrolizumab, pembrolizumab) + Inlyta (axitinib, axitinib) first-line treatment of metastatic renal cell carcinoma with poor performance status (poor PS) (mRCC) patients, there were no significant differences in overall response rate (ORR), progression-free survival (PFS), and overall survival (OS) .
-
Can AIDS be cured?
Time of Update: 2022-04-30
Abstract: Bone marrow transplantation containing the CCR5 mutation gene may be suitable for the treatment of patients of different races and genders who suffer from AIDS and blood cancer at the same time .
-
The new "revolution" of cell therapy, a number of giant companies in NK therapy have joined forces
Time of Update: 2022-04-30
The therapy CYNK-001 is a cryopreserved allogeneic ready-to-use NK cell therapy, unmodified, containing CD56+/CD3-NK cells expanded from human placental CD34+ cells, intended to be developed for the treatment of the blood system Malignant tumors, solid tumors and infectious diseases .
-
Treatment of Breast, Colon and Pancreatic Cancers Nature Study Finds Potential New Combination Therapy
Time of Update: 2022-04-30
The researchers systematically evaluated 2,025 two-drug combinations using 125 tumor cell lines, including breast, colorectal, and pancreatic cancer cell lines .
-
14 products of Sino Bio have obtained medical device registration certificate
Time of Update: 2022-04-30
Insulin (INS) detection kit (chemiluminescence immunoassay) for the quantitative determination of the content of insulin (INS) in human serum or (and) plasma in vitro;12.
C-peptide (CP) detection kit (chemiluminescence immunoassay) for quantitative determination of the content of C-peptide (CP) in human serum or (and) plasma in vitro;14.
-
Science Sub-Journal: Human Orthogonal IL-2/IL-2Rβ System Enhances the Proliferation and Antitumor Effects of CAR-T Cells
Time of Update: 2022-04-29
In this preclinical model, administration of ortho-hIL-2 to mouse recipients receiving CAR-T cell transplantation expressing ortho-hIL-2Rβ promoted CAR-T cell activation, proliferation, and antitumor efficacy with Limited systemic toxicity .
-
Bayer files for expansion of Nubeqa indication in US and EU
Time of Update: 2022-04-29
The filing is based on data from the ARASENS Phase 3 trial showing a statistically significant improvement in overall survival with Nubeqa combined with androgen deprivation therapy (ADT) and chemotherapy docetaxel in men with metastatic hormone-sensitive prostate cancer .
-
Cancer Cell: Revealing the mechanism of arachidonic acid and interferon-gamma synergistically induce ferroptosis in tumor cells
Time of Update: 2022-04-29
In a new study, researchers from the University of Michigan's Roger Cancer Center found that a cytokine and a fatty acid work synergistically to trigger a type of cell death previously identified by studies of synthetic molecules .
-
Science Sub-Journal: An Orthogonal IL-2/IL-2Rβ System Promotes Persistence of CAR-T Cells and Enhances Tumor Clearance
Time of Update: 2022-04-29
In this preclinical model, administration of STK-009 to mouse recipients receiving hoRb-expressing CAR-T cell transplantation promoted CAR-T cell activation, proliferation, and antitumor efficacy with limited systemic toxic side effects .
-
ACS Nano: Chinese scientists have developed a conductive nerve conduit based on the lepidopterus of the Great Blue Morpho butterfly
Time of Update: 2022-04-29
The researchers obtained an artificial nerve guide catheter by crimping the conductive scaffold, which can effectively promote the regeneration of nerve and muscle and the recovery of motor function in a rat model of 10mm sciatic nerve defect .
-
Corning Jereh to Announce Clinical Study Data of KN026 Combined with KN046 in HER2-Positive Solid Tumors at AACR Annual Meeting 2022
Time of Update: 2022-04-29
S. FDA approved KN046 to directly enter Phase II clinical trials in the United States based on the clinical trial results obtained in Australia and China, and granted orphan drug designation for KN046 for the treatment of thymic epithelial tumors in September 2020 .
-
Science: The latest discovery!
Time of Update: 2022-04-29
Recently, in a research report titled "Angiotensin-converting enzyme gates brain circuit–specific plasticity via an endogenous opioid" published in the international journal Science, scientists from the University of Minnesota School of Medicine and other institutions found through research that blood pressure drugs may It has an unexpected effect on the brain of the body .
-
NICE rejects Merck's Keytruda for triple-negative breast cancer
Time of Update: 2022-04-29
CompilenewbornRecently, the National Institute for Health and Clinical Excellence (NICE) issued a draft guidance rejecting approval of Merck's anti-PD-1 therapy Keytruda (pembrolizumab) in combination with chemotherapy for the treatment of metastatic triple-negative breast cancer (mTNBC).
-
PNAS: Bats promote virus transmission via salivary gland immunosuppressive toxin
Time of Update: 2022-04-29
A joint team led by Lai Ren, a researcher at the Kunming Institute of Zoology, Chinese Academy of Sciences, found that bats may promote virus residency and transmission through their salivary gland immunosuppressive toxins .
-
Diabetologia: A New Breakthrough in Diabetes Research!
Time of Update: 2022-04-29
Recently, in a research report titled "Endothelial glycocalyx is damaged in diabetic cardiomyopathy: angiopoietin 1 restores glycocalyx and improves diastolic function in mice" published in the international journal Diabetologia, scientists from the University of Bristol and other institutions found through research , a drug that repairs damage to the gel-like layer in the tiny blood vessels of the heart may help treat heart failure in people with diabetes .
-
Nat Commun: Special protein activity may reveal novel combination therapy for childhood acute lymphoblastic leukemia
Time of Update: 2022-04-29
March 6, 2022 /Bio Valley BIOON/ --Recently, in a research report titled "Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strateg
-
npj Precis Onc: Scientists reveal new mechanism of melanoma resistance to therapy
Time of Update: 2022-04-29
Recently, a research report entitled "Proximity of immune and tumor cells underlies response to BRAF/MEK-targeted therapies in metastatic melanoma patients" was published in the international journal npj Precision Oncology, from Vanderbilt University Medical Center and other institutions.
-
Allogeneic cell therapy for the treatment of solid tumors received fast track designation
Time of Update: 2022-04-29
This is also the company's first clinical candidate AlloCAR T therapy for the treatment of solid tumors and is expected to treat advanced or metastatic clear cell renal cell carcinoma .
-
Lepu Medical's novel coronavirus antigen detection kit obtained product registration certificate
Time of Update: 2022-04-29
On March 14, 2022, Lepu Medical announced that the new coronavirus antigen detection kit (colloidal gold method) developed by the company's holding subsidiary Lepu Diagnostics was approved by NMPA on
-
Science: Study reveals mechanism of spindle spindle instability in human oocytes
Time of Update: 2022-04-29
Recently, a research team from the Max Planck Institute in Germany published an article entitled "Mechanism of spindle pole organization and instability in human oocytes" in "Science" and found that the lack of the molecular motor KIFC1 (kinesin superfamily protein C1) would Causes instability of the human oocyte spindle .
