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Yanfeng Zhang's group and collaborators have made important progress in the controllable preparation and magnetic properties of novel self-inserting phase iron selenide nanomaterials
Time of Update: 2023-02-02
Recently, Professor Zhang Yanfeng's research group and his collaborators from the School of Materials Science and Engineering of Peking University prepared a new iron selenide nanomaterial with iron self-inserting layer structure by chemical vapor deposition, and obtained two-dimensional iron selenide materials with room temperature ferromagnetic properties by adjusting the proportion of iron intercalation, and the related work was published in Advanced Materials.
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Cancer Cell provides new evidence: deleting a gene turns normal cells into cancer cells
Time of Update: 2023-02-02
"ArticleKMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition A team led by researchers at the Permatt Cancer Center at NYU Langone Health Center has identified a gene that drives the development of the second most common type of lung cancer, providing deeper insights into how to treat the disease.
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Nature: Prevention/treatment opens new doors, inhaled nanoparticles effectively deliver mRNA to the lungs
Time of Update: 2023-02-02
In February 2021, Philip Santangelo's team published a paper in Nature Materials on the use of Poly-β-amino esters (PBAEs) aerosols to deliver CRISPR-Cas13a mRNA to the respiratory tract, which can effectively treat influenza virus and COVID-19 infection in mice and hamsters 。 In this latest study, to improve the delivery of PBAE preparations to the lungs, the research team evaluated 166 PBAE and PBAE-containing preparations in mice using a combined synthesis strategy and a low-dead volume nebulizer-based particle screening system.
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Revealing the metabolic characteristics of the common ancestor of deep-sea hydrothermal archaea bacteria
Time of Update: 2023-02-02
In this study, the 3D structure of nearly 10,000 protein molecules was predicted by applying high-throughput AlphaFold2 deep learning technology, and the protein structure group was introduced, and the metabolic characteristics of the common ancestor of archaea bacteria were reconstructed by comparing and analyzing the sequence, structure and function of ancient superthermophilic archaea and representative strains of thermophilic bacteria with similar metabolic functions from deep-sea hydrothermal sources.
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Nature: How does the new crown affect the immune system? Scientists found that the T cell activity profile of new crown survivors was elevated, and male recovered people had a stronger immune response to influenza vaccines
Time of Update: 2023-02-02
There are significant gender differences in the impact of coronavirus infection on immunityThe researchers then analyzed and compared the immune responses of these participants after receiving the flu vaccine.
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Chinese Academy of Sciences scholar Cell issued an article: The revival of human genome archaeviruses drives aging
Time of Update: 2023-02-02
The co-evolutionary relationship between viruses and humans has a long history, and the confrontation between the two has never stopped over time. In this protracted war, on the one hand, viruses mak
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Lost in translation: how "dangerous" amino acids abort the extension of protein synthesis
Time of Update: 2023-02-02
Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes Source: Tokyo Institute of TechnologyLife depends on the precise function of several proteins synthesized by ribosomes in cells.
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Current methods of assessing genetic relationships between traits are flawed
Time of Update: 2023-02-02
Study co-author Noah Zaitlen, a professor of computational medicine and neurology at UCLA Health Center, said: "Selective mating across traits affects all of our genomes and creates interesting correlations across the genome between the DNA you inherit from your mother and the DNA you inherit from your father.
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Digital PET team successfully develops the second generation of "digital PET"
Time of Update: 2023-02-02
The new generation of clinical all-digital PET/CT 930 single-bed imaging speed ranks first in the world According to the reporter of Hubei Radio and Television Financial Media, the first PET/CT imported from the United States in Hubei Province was settled in the PET Center of Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology in 2003.
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Inflammation has triggered new clues to Alzheimer's disease
Time of Update: 2023-02-02
"essayPathogenic tau–induced transposable element–derived dsRNA drives neuroinflammation Scientists at the University of Texas San Antonio Health Sciences Center (UT Health SAN ANTONIO) reported today that inflammatory triggers present during viral infections are elevated in Alzheimer's disease and progressive supranuclear palsy, a rare brain disease.
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Targeted RNA to prevent dementia that penetrates the blood-brain barrier
Time of Update: 2023-02-02
This study identified a small molecule drug candidate that can break through the blood-brain barrier and selectively eliminate the G4C2 abnormally amplified RNA fragment of the C9orf72 gene that causes cryomorphic and frontotemporal dementia, restoring the health of faded neurons and mouse models.
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New iScience study explains why obesity is more dangerous for men
Time of Update: 2023-02-02
A newly published study from the University of York reveals the biological basis of sex differences in obesity-related diseases, with researchers observing "significant" differences in the cells that build blood vessels in adipose tissue of male and female mice.
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Hope for the future? Ferritin nanoparticle vaccines protect against all SARS-CoV-2 variants
Time of Update: 2023-02-02
The author is the inventor of Stanford University and Chan Zuckerberg Biohub patenting immunogenic coronavirus fusion proteins and related methods, which have been licensed to Vaccine Inc. While the rapid development of COVID vaccines is a scientific victory, there is still a need for a globally available vaccine that can provide lasting immunity against current and future SARS-CoV-2 variants (VOCs).
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Cell and two other articles reported on the largest autism study to date, discovering hundreds of new genes
Time of Update: 2023-02-02
Reuter, Zhuozhi Wang, Bhooma Thiruvahindrapuram, Brett Trost, Thomas Nalpathamkalam, Carol Negrijn, Sylvia Lamoureux, Giovanna Pellecchia, Rohan V.
Reuter, Zhuozhi Wang, Bhooma Thiruvahindrapuram, Brett Trost, Thomas Nalpathamkalam, Carol Negrijn, Sylvia Lamoureux, Giovanna Pellecchia, Rohan V.
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The new report says plastic pollution in the oceans affects not only the environment, but also the human population
Time of Update: 2023-02-02
Image: This illustration by Seattle-based artist Mari Shibuya depicts how plastic waste of different sizes can pass through the marine environment and end up in fish, beaches or people.
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Circulation: Immune response and proteins in the blood of young people who develop rare complications after COVID mRNA vaccination
Time of Update: 2023-02-02
The risk of severe COVID-19 continues to outweigh the rare risk of myocarditis after vaccinationIn adolescents and young adults who developed this rare complication, the researchers found no difference in antibody production, autoantibodies, T cell profiles, or prior viral exposure, but detected elevated spike protein levelsThe findings point to potential treatments to prevent or reverse post-vaccine myocarditisMyocarditis is a condition of myocardial inflammation that is a rare complication that can occur after receiving the mRNA COVID vaccine.
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Science Advances: The average age at conception for men and women over the past 250,000 years
Time of Update: 2023-02-02
Now, researchers at Indiana University have developed a new method using DNA mutations that can determine the average age at which women and men have children in human evolutionary history.
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Blood type can also affect health! People with blood type A are more likely to have a stroke before the age of 60!
Time of Update: 2023-02-02
Figure 2 Research results (Source: [2])Ischemic stroke, which is caused by obstructed blood flow to the brain, accounts for 87% of all strokes, while early-onset stroke is defined as occurring before the age of 60.
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Good news for Cell! Scientists have pinpointed the entry and exit ports of the new coronavirus inside our noses
Time of Update: 2023-02-02
In a study published Jan. 5 in the journal Cell, Dr. Peter Jackson, a professor of pathology, microbiology and immunology at Stanford University, and his colleagues brought this possibility closer to reality by pinpointing the pathways through which SARS-CoV-2, the virus of COVID-19, enters and leaves our nasal cells.
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Challenge the endophytic view of bacterial evolution: in addition to host cells, chlamydia can also use the environment to evolve!
Time of Update: 2023-02-02
Gene gain facilitated endosymbiotic evolution of Chlamydiae Chlamydia, known as the bacterial pathogen of humans, originally evolved in single-celled microbes long before acquiring the ability to infect humans.
