-
"Cell": Qin Chengfeng/InBev/Wang Youchun team develops a new type of mRNA vaccine for COVID-19
Time of Update: 2020-07-31
in mouse and non-human primate models, the vaccine stimulates an immune response and induces the production of neutralizing antibodies.
in mouse models, after receiving one injection, the animals had IgG antibodies against the new coronavirus RBD, as well as antibodies to the neutral and crown virus.
-
Neuron: Cells react differently to genetic imprints.
Time of Update: 2020-07-30
Simon Hippenmeyer, a professor at the Austrian Institute of Science and Technology (IST Austria), and his team, including Postdoc Susanne Laukoter and senior laboratory technician Florian Pauler, have shown that brain cells respond very differently to genomic imprints, depending on cell type.
-
New postoperative pain relief drugs! The new non-opioid painkiller Zynrelef (Bubicain/Meloxicon) has been approved by THE EUROPEAN Union CHMP!
Time of Update: 2020-07-30
note, the drug is the first and only long-acting, slow-release local anaesthetic: in Phase III studies, it has been shown to significantly reduce pain and opioid use in 72 hours compared to the current standard of care for postoperative pain control, the local anaesthetic bubbly solution.
-
2 cases of aneurysm in the brain that were completely thrombosis.
Time of Update: 2020-07-30
line of high-resolution MRI-enhanced scanning, left outer cracking circular lesions, T1WI is uneven and other low signals, the boundary is clear, the tumor wall thickens, the inner and lower tumor wall is significantly strengthened, the surrounding can be seen low density cerebrospinal fluid ring (Figure 2B, C, D).
-
CELL: Immune cells can get into the brain! It also helps cells in the brain mature.
Time of Update: 2020-07-30
single-cell sequencing showed that, in the absence of mouse CD4 T cells, resident small glial cells in the brain remained between the fetus and the adult.
-
Nature: Revealing the role of phase separation in neurodevelopmental diseases!
Time of Update: 2020-07-30
"There is a chemical syntax to be deciphered to explain the difference in the ability of certain proteins to transform into one condensat !--e and another," says !--.ewebeditor." finding these mechanisms can help us understand how cells maintain a critical balance between the active and silent parts of our genome, and how to treat diseases like rett syndrome.
-
Nature: Feng Guoping/ Fu Zhanyan/Li Yuqing, etc. to uncover the mystery of the chukes mesh core.
Time of Update: 2020-07-30
it is thought to play a "gated" role in the transmission of information between the thysukal brain and the cortex, that is, like a gate to filter the sensory information, thereby regulating the body's sensory information processing, attention and sleep behavior, but because of the current knowledge of the basic tissue composition of the thalamus mesh nucleus, it is not possible to clarify its working mechanism.
-
NATURE: Dynamic changes in heterogeneous chromatin affect the neurodevelopment of patients with Rett syndrome.
Time of Update: 2020-07-30
therefore, the researchers suggest that MeCP2 enhances the separation of heterogeneous/constant chromatin through its coagulation concentration properties, and that the destruction of clots may be a common consequence of mutations found in RTT patients.
-
1 case of hematoma under the epidural after surgery of the skull bile lioma.
Time of Update: 2020-07-30
!----, or epidermal cyst, is found in the corner region of the bridge cerebellum and rarely originated in the skull; Changshu City Second People's Hospital recently admitted a case of right frontal c
-
2020 POST-ASCO: The current situation and future of glioblastoma treatment.
Time of Update: 2020-07-30
if the patient adheres well and follows the guidelines for electro-field therapy, the patient's median survival will be more than 20 months, which is currently the ideal method for the treatment of glioma.
-
J Neurol Neurosur Ps: Smoking and intracranial aneurysm risk in middle-aged women.
Time of Update: 2020-07-30
!---- A previous single-center study showed that smoking increased the risk of ruptured intracranial aneurysms (UIA) in women between the ages of 30 and 60 sixtimes, and that the risk was higher if the patient had chronic hypertension.
-
Cell . . . The IL-33 mediated glial cell phagocytosis of neurons promotes synaptic remodeling.
Time of Update: 2020-07-30
the study found that adult hippocampus neurons expressIL-33 in an empirically dependent manner, acting on IL-33 receptors on small glial cells and promoting the swallowing of damaged extracellular matrix (Extracellular Matrix ECM).
-
JAMA Diagnosticy: This base knot is high signal and should not be misdiagnosed as acute stroke.
Time of Update: 2020-07-30
nervous system check shows left upper limb dance samples and throwing-like movements, denied recent infections, family medication was carefully checked to eliminate drug-induced dance disorders.
despite positive corrections of blood sugar levels and metabolic indicators, the patient's dance-like movement did not ease.
-
Nature: Nervous system is the key to weight loss! Neurons reshape body fat to control its burning!
Time of Update: 2020-07-30
photo source: Laboratory of Molecular Genetics at The Rockefeller University, if confirmed in humans, the discovery will advance research into obesity and related diseases and could open the door to the development of new treatments for neurons in fat.
-
Cell: Reveals the cell and molecular mechanisms of the development of less protrusion cells in human embryos and the expansion of white matter in the cerebral cortex.
Time of Update: 2020-07-30
combined with the above findings, these three properties of the less protrusion precursor cells in human embryonic development (additional sources, continuous division, rapid diffusion) will significantly increase the production of small-burst glial cells, thus promoting the expansion of white matter in the cerebral cortex.
-
Eur Heart J: Half of strokes are related to cardiovascular disease, and stroke treatment requires a cardiologist! Review by the European Heart Journal.
Time of Update: 2020-07-30
but the elderly, obvious atrial increase cause unknown cause of embole stroke patients oral anticoagulant drugs than aspirin benefits more.
unexplained embolic stroke patients are not a sign of initiating a new oral anticoagulant drug, but an extension of electrocardiogram monitoring may be considered.
-
Sci Rep: Leukemia drug shows hope for childhood brain cancer!
Time of Update: 2020-07-30
in the study, the researchers selected different SHH tumor cell lines and tested different doses of arsenic trioxide, a drug used to treat acute myeloid leukemia.
-
Acta Neuropathologica: HIF-1 alpha is associated with the blood-brain barrier dysfunction of pneumococcal meningitis and the extracellular migration of bacteria.
Time of Update: 2020-07-30
method: Collect edified mouse meningitis specimens and human meningitis (including bacterial, viral, fungal, or parasitic meningitis infections) from mice buried in Formarin's fixed paraffin, and studied the activation of HIF-1 alpha using immunohistochemical methods.
-
Nat Neurosci: Tang, etc. reveals the neurobiological mechanisms behind "social care."
Time of Update: 2020-07-30
a particular hypothesis is that hugging and touching trigger a neuropeptide: oxytocin (Oxytocin, OT) release that makes people feel physically and mentally pleasing and has a sense of trust, but for years it has been difficult to prove from a neuroscience perspective because of the lack of technical means.
-
A selection of BMJ research highlights from July 25, 2020.
Time of Update: 2020-07-30
but in children 4 years and older, NEWSUP had no significant effect on working memory or anaemia, but had an increase in lean tissue content (4.31 cm2) compared to FBF.
