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The brain will also "one area with two functions", and the neurons that control habits also learn new behaviors.
Time of Update: 2021-10-01
▎The content team editor of WuXi AppTec recently, in a study on rodents, scientists at the Icahn School of Medicine at Mount Sinai discovered that the part of the brain traditionally believed to control old habits , May also play a key role in learning new behaviors.
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Science-PINS award-winning research introduces the concerted regulation of the brain: two-photon holographic technology helps optogenetics enter the era of precise regulation of neural circuits
Time of Update: 2021-10-01
In order to effectively regulate neural activity, we need to stimulate a group of neurons scattered in the three-dimensional brain at the same time-just like we need to use ten fingers of both hands to play a coordinated piano music .
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Intervention barrier moves forward, precise diagnosis and treatment delays the progress of AD
Time of Update: 2021-10-01
AD grasp early intervention "time window", AD patients expected to delay progression to dementia five years Professor Chen Xiaochun that "the next 10--20 years may be the key to the development of the treatment of AD" .
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Express sword refers to a variety of neurodegenerative diseases, Xinrui receives 85 million US dollars in assistance
Time of Update: 2021-10-01
The funds obtained in this round of financing will be used to advance the development of innovative treatments for neurodegenerative diseases, including Parkinson's disease (PD), Gaucher disease (GD), Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS) .
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Express delivery doubles painless patients within 2 hours, oral multi-mechanism migraine therapy is expected to be approved next year
Time of Update: 2021-10-01
▎ WuXi AppTec content team editor On September 14, 2021, Axsome Therapeutics announced that the US FDA has accepted a new drug application (NDA) for the compound migraine therapy AXS-07 with multiple mechanisms of action for the acute treatment of migraine, PDUFA The target date is April 30, 2022 .
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Thrombolysis, dissection, infarction... twists and turns
Time of Update: 2021-10-01
According to the medical history, the patient has chest pain accompanied by numbness and weakness of the left lower extremity, physical examination of left lower extremity muscle strength, decreased left lower extremity pain and tactile sensation, and positive left Babinski sign.
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Their discoveries in the brain have solved the puzzles that have plagued philosophers for centuries
Time of Update: 2021-10-01
When the animal reaches a specific position, the cells in the hippocampus (the position shown in the color on the right) send out a high-speed discharge signal (picture source: reference [1]) at O' It seems to Keefe that now they may have found the neural basis for Kant's a priori sense of space .
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Break through the blood-brain barrier!
Time of Update: 2021-10-01
Recently, the top medical journal "The Lancet-Neurology" in the field of neurology published online the results of a phase II study of the oral permeable BTK inhibitor Tolebrutinib in the treatment of relapsed MS [3].
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Regarding the psychobehavioral symptoms of AD, these 5 points should be clarified
Time of Update: 2021-10-01
In 2017, the "Expert Consensus on Clinical Diagnosis and Treatment of Neurocognitive Disorders and Mental Behavior Symptoms" formulated by the Geriatric Psychiatry Group of the Psychiatric Branch of the Chinese Medical Association and written by Professor Wang Huali was released [3] .
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Science: This immune molecule actually caused sleep disorders and epilepsy related to traumatic brain injury
Time of Update: 2021-10-01
Paz research team at the University of California found that the expression of complement C1q was up-regulated in the cortex and thalamus through a model of chronic traumatic brain injury.
Reducing C1q levels by neutralizing antibodies can reduce glial cell inflammation and reduce neuronal loss in mice with traumatic brain injury .
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I heard that this case of cerebral infarction can test your diagnostic level!
Time of Update: 2021-10-01
Plain scan (red arrow) shows high-density thrombus in the transverse sinus and bleeding in the infarct area.
CT-enhanced sagittal view shows the filling defect of the rectilinear sinus and the great cerebral vein (Blue Arrow) Summary: After reading this article, what will everyone think?
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Exploration Miraculous "Nano-Neurotrophic Factor" Blocks Nerve Injury-Alcoholism
Time of Update: 2021-10-01
The content of this article is based on the "Receptor-targeting nanomaterials alleviate binge drinking-induced neurodegeneration as artificial neurotrophins" published in the Research Article in the first issue of the first volume of the Wiley Publishing Group's cooperative journal Exploration DOI: 10.
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How does secondary brain injury occur after head trauma?
Time of Update: 2021-10-01
The results showed that: 3 weeks after mTBI injury in mice, chronic inflammation and neuronal loss occurred in the cortex and its function-related thalamus, and the expression of C1q increased .
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Neurosci Bull︱ synapse-associated protein Dlg1 improves depression-like behavior in mice by inhibiting microglia activation
Time of Update: 2021-10-01
On September 6, 2021, the joint team of Professor Yuan Zengqiang from the Academy of Military Medical Sciences and Associate Professor Cheng Jinbo from Minzu University of China published an online publication entitled "Dlg1 Knockout Inhibits Microglial Activation and Alleviates Lipopolysaccharide-induced Depression-like Behavior in Mice" on the Neuroscience Bulletin.
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What do peppers, boiling water and poisonous spiders have in common?
Time of Update: 2021-10-01
▲Professor David Julius won the 2020 "Scientific Breakthrough Award" for discovering molecules, cells and mechanisms related to pain perception (picture source: reference [3]) In 2013, structural biologist Professor Cheng Yifan and Professor David Julius collaborated in "Nature" published a paper, showing the cryo-EM structure of TRPV1 for the first time with an atomic resolution of 3.
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Huazhong University of Science and Technology Xu Shunqing, Shengxia & Tang Yaohui, Shanghai Jiaotong University Advanced Science: Endoplasmic reticulum stress-mediated neurodevelopmental toxicity mechanism of early life exposure of benzophenone
Time of Update: 2021-10-01
This study reveals the mechanism by which 4HBP induces developmental defects in the hippocampus and impaired cognitive function by inducing the imbalance of endoplasmic reticulum protein homeostasis and inflammation, suggesting that the use of nursing products containing benzophenones during pregnancy may affect offspring Neurodevelopment provides a theoretical basis at the molecular level for preventing the neurodevelopmental toxicity of benzophenone .
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Demystifying the cause of addiction!
Time of Update: 2021-10-01
Subsequently, the researchers conducted a more in-depth mechanism study on the above phenomenon, focusing on exploring the potential mechanism of whether repeated exposure to cocaine could reduce the selective sensitivity of D2Rs by differentially regulating the Gα protein level in this region .
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Thanos' glove-the upper right limb was stiff for July, why on earth?
Time of Update: 2021-10-01
Case review: A 36-year-old man, married, was admitted to the hospital in September 2020 due to "paroxysmal right upper limb stiffness for 7 months and aggravation in April" .
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Into the "King of Children's Tumors"...
Time of Update: 2021-10-01
Professor Yuan Xiaojun, director of the Department of Pediatric Hematology and Oncology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, "Because cases of abdominal tumors are the most common, the clinical manifestations of neuroblastoma are mostly abdominal masses .
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Alzheimer's disease can be latent for 20 years before the onset of disease. Two major measures can help you prevent its progression!
Time of Update: 2021-10-01
In 2019, Professor Han Ying's research group carried out a study on non-pharmaceutical intervention therapy of light stimulation for SCD population and normal elderly, and found that light therapy is effective in improving the cognition of the elderly .
