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NeuroImage: Counterintuitive decision-making behavior in complex value decisions is associated with fronto-parietal executive control function
Time of Update: 2022-02-19
Probabilistic behavioral effects are stronger than delayed behavioral effectsBrain activation correlates with probabilistic processing and latency in multifactorial tasks .
A meta-analysis of brain activity suggests an explanation that paradoxical increases in reaction time may be related to strategy switching .
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Neurology: Association of disease-modifying antirheumatic drugs with Parkinson's disease risk
Time of Update: 2022-02-19
RDisease-Modifying Antirheumatic Drugs and Risk of Parkinson Disease: Nested Case-Control Study of People With Rheumatoid Arthritis .
0000000000013303RDisease-Modifying Antirheumatic Drugs and Risk of Parkinson Disease: Nested Case-Control Study of People With Rheumatoid ArthritisLeave a Comment here
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JPD: Parkinson's, motor symptoms progression, synchrony with disease progression
Time of Update: 2022-02-16
However, data from some prospective follow-up cohorts suggest that the motor phenotype is not fixed and can change over time, with patients initially identified as TD switching to another phenotype after only 1 year of follow-up .
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JPD: What does smoking marijuana have to do with Parkinson's?
Time of Update: 2022-02-16
Studies have shown that activation of cannabinoid receptors can improve tremors in animal models .
Preclinical studies have shown that activation of CB1 receptors can reduce dyskinesia in animal models of PD .
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Neuron: Dr. Zepeng Yao from the University of California, et al. report that the serotonin loop can regulate eating and energy balance
Time of Update: 2022-02-16
(figure 1) Figure 2: Regulation of taste perception and physiological function by two distinct serotonergic neuron subtypes in Drosophila .
)Figure 2: Regulation of taste perception and physiological function by two distinct serotonergic neuron subtypes in Drosophila .
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Neuromodulation: A retrospective study of short-term peripheral nerve stimulation for pain relief in elderly patients with herpes zoster ophthalmia
Time of Update: 2022-02-16
Compared with baseline examination, NRS scores at different time points after short-term PNS were significantly lower (p at different time points after treatment, SF-36 scores (including general health, social functioning, emotional role, mental health, physical pain, physical function, Body role and vitality) were significantly improved (p Mean doses (mg/d) of tramadol and pregabalin were both significantly lower than baseline (p
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Nat Med: Silencing FUS expression with antisense oligonucleotides treats amyotrophic lateral sclerosis
Time of Update: 2022-02-16
In this disease-associated mouse model of ALS-FUS, researchers found that ION363, a non-allele-specific FUS antisense oligonucleotide, effectively silences Fus and reduces levels of FUS protein in the brain and spinal cord , thereby delaying motor neuron degeneration .
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2021 year-end inventory of neurological imaging reading good articles
Time of Update: 2022-01-27
Stroke In acute stroke settings, neuroimaging plays an important role: to confirm or exclude the diagnosis of cerebrovascular disease (ischemic or hemorrhagic); to provide evidence of possible stroke pathogenesis (embolic, hemodynamic, etc.
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Scientific stroke prevention diet!
Time of Update: 2022-01-27
For stroke classification, after adjusting for various potential confounders, further analysis found that adherence to the EAT-Lancet diet was associated with a 70% lower risk of subarachnoid hemorrhage (HR=0.
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Basic Research Neurology: Beware!
Time of Update: 2022-01-27
Compared with the non-exposed group, participants exposed for ≥22 years had a higher risk of cognitive impairment, such as short-term memory impairment (aRR: 1.
Higher cumulative exposure to formaldehyde (high CEI) was also significantly associated with risk of cognitive impairment for most items tested (aRR: 1.
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The first prescription of satrilizumab landed in my country, filling the gap in domestic NMOSD treatment!
Time of Update: 2022-01-27
On April 30, 2021, satrilizumab was officially approved by the China National Medical Products Administration for the treatment of aquaporin-4 immunoglobulin G antibody (AQP4-IgG)-positive neuromyelitis optica spectrum in patients over 12 years of age disease (NMOSD) patients, becoming the first drug approved for NMOSD treatment indications in China .
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Drinking too much coffee increases dementia risk by 53%
Time of Update: 2022-01-27
Another area of interest in the brain is white matter hyperintensity (WMH), a small lesion often associated with localized small blood vessel damage, associated with increased risk of stroke and dementia .
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Advanced treatment or early and efficient treatment, how to choose the initial treatment plan for multiple sclerosis?
Time of Update: 2022-01-27
Long-term disability trajectories in relapsing multiple sclerosis patients treated with early intensive or escalation treatment strategies[J].
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Hypertrophic dura mater, motor neuron disease, hypotension syndrome
Time of Update: 2022-01-27
Answer: Hypertrophic pachymeningitis (HP) is a group of diseases characterized by focal or diffuse dura mater hypertrophy, with chronic headache, multiple groups of cranial nerve damage, and focal brain damage as the main clinical manifestations.
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JAMA sub-issue: AI AI accurately predicts who will develop dementia within two years
Time of Update: 2022-01-27
The research developed a machine-learning clinical decision aid that can uncover hidden patterns in examination data, analyze people at high risk of developing dementia in the next 2 years in memory clinics, and help reduce clinical misdiagnosis rates of dementia .
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Top 12 neurology classic cases in 2021, help you develop clinical thinking year-end inventory
Time of Update: 2022-01-27
>>>Click here to view the case Other wonderful cases: ➤71-year-old male horizontal gaze paralysis, loss of speech ability, quadriplegia, this disease should be thought of ➤ If you encounter this patient with polycranial neuropathy, will you diagnose and treat it?
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Nat Neurosci︱Cao Peng's lab discovers the important function of pain in the struggle for survival among species
Time of Update: 2022-01-27
To investigate the link between noxious mechanical stimulation, the authors used a calcium imaging fiber optic recording system, injected AAV-DIO-GCaMP7 into the AHN brain region of vGAT-IRES-Cre mice, and observed when vGAT+ AHN neurons received different stimuli in different scenarios.
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Nature's latest review: In-depth pathology, to explore the only drug that meets the six criteria for MS progression treatment?
Time of Update: 2022-01-27
Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system, which has attracted much attention in recent years as a neuroimmune disease . From a clinical point
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Cerebral infarction emergency, big coffee teaches you to see through CT films!
Time of Update: 2022-01-27
● Infarction core and penumbra, DWI combined with PWI can more accurately determine the prognosis of patients Blood flow can reach the ischemic area through other blood vessels (collateral or newly formed vascular anastomosis), so that the ischemic tissue can be compensated by different degrees of perfusion .
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Cell reviews the era of brain science 2.0
Time of Update: 2022-01-26
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