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The FDA approved an adenovirus gene therapy for the treatment of bladder cancer
Time of Update: 2022-12-30
Dr. Peter Marks, director of the FDA's Center for Biologics Evaluation and Research, said the approval provides healthcare professionals with an innovative treatment option for patients with high-risk non-muscle-invasive bladder cancer who do not respond to BCG therapy.
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Nature sub-journal: reported that scaffolding protein phase separation regulates microbial cell polarity
Time of Update: 2022-12-30
Recently, the team of Zhao Guoping/Zhao Wei of Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, published research results entitled Phase separation modulates the assembly and dynamics of a polarity-related scaffold-signaling hub in Nature Communication 。 The study found that scaffolding proteins formed polar membrane-free compartments with cell fate determination function through phase separation, revealing a new mechanism of polar construction and dynamic regulation of microbial cells.
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New progress has been made in the participation of bacterial toxin-antitoxin system in the regulation of bacteriophage life cycle
Time of Update: 2022-12-30
The authors identified by RNA-seq that signal short peptides promote the expression of a downstream gene cluster during bacteriophage infection with bacteria, and further determined that yopM genes inhibit the cleavage cycle of bacteriophages, and yopR genes promote the occurrence of lysogens.
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Large real-world studies have shown that vaccination is more effective than natural immunity
Time of Update: 2022-12-30
This first large, real-world study comparing COVID vaccines with natural immunity in preventing deaths, hospitalizations, and emergency department visits from any cause, including COVID, showed that people of all age groups benefited significantly more from vaccination than natural immunity from COVID infection, and that those who received the vaccine had a lower mortality rate, especially among adults over 60.
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Professor Liu Ronghou's team from Shanghai Jiaotong University published a review paper on two-stage anaerobic fermentation coupled with in-situ biogas purification in BioresourceTechnology
Time of Update: 2022-12-30
On December 9, 2022, Liu Ronghou, a long-term professor at the Biomass Energy Engineering Research Center of the College of Agriculture and Biology of Shanghai Jiao Tong University, officially published the "Integration of two-stage anaerobic digestion process" in the well-known journal Bioresource Technology (SCI, Region 1, Chinese Academy of Sciences, Top Journal, Impact Factor 11.
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Yu Yang's research team from the Department of Obstetrics and Gynecology of Peking University Third Hospital published the research results of the mechanism of ginsenoside Rb1 protection against oxidative stress-induced ovarian granule cell damage in Science China-Life Sciences
Time of Update: 2022-12-30
Ginsenoside Rb1 interacts with FoxO1 by activating phosphorylation at the Akt Ser473 site, thereby inhibiting the molecular pathway of oxidative damage in granule cells Science China-Life Sciences, co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China, was selected as a key journal of the Excellence Action Plan for Chinese Science and Technology Journals and ranked TOP5% in the international JCR field of biology.
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After AlphaFold: The protein folding contest seeks the next big breakthrough
Time of Update: 2022-12-30
London-based DeepMind has just enjoyed success in a biennial competition co-founded by Moult that tests the team's ability to predict protein structure with its revolutionary artificial intelligence (AI) tool, AlphaFold, one of biology's toughest challenges.
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Intermittent fasting can achieve complete diabetes remission
Time of Update: 2022-12-30
"The researchers administered an intermittent fasting diet intervention to 36 people with diabetes for 3 months and found that nearly 90 percent of participants, including those taking hypoglycemic drugs and insulin, reduced their diabetes medication intake after intermittent fasting.
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A new toxic phenomenon: yeast is not a simple microorganism that we have always thought of
Time of Update: 2022-12-30
A recently discovered phenomenon known as "latecomer killing" describes how yeast kills its own clones and other nearby microbes to survive when it lacks glucose.
A recently discovered phenomenon known as "latecomer killing" describes how yeast kills its own clones and other nearby microbes to survive when it lacks glucose.
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A parasite infects up to 30% of humanity's secret: cells become "zombies"
Time of Update: 2022-12-30
Toxoplasma gondii causes infected cells that should not be transmitted in the body to move rapidly, allowing the parasite to spread to different organs.
Toxoplasma gondii causes infected cells that should not be transmitted in the body to move rapidly, allowing the parasite to spread to different organs.
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New research has found that animals play a key role in restoring forests
Time of Update: 2022-12-30
Comita and Estrada-Villegas say the study's most important findings are the role that flightless animals play in seed dispersal across all forest ages, from 20 to old age, and the diversity of animal species involved, and point to the importance of natural forest regeneration.
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The joint team of Xie Xiaoliang / Cao Yunlong cracked the evolution trend of the new coronavirus, and broad-spectrum antibodies added new weapons against the epidemic
Time of Update: 2022-12-30
Abstract: Since the emergence of the new coronavirus Omicron variant, its offspring variants have emerged in a blowout and shown a trend of "convergent evolution", and a large number of neutralizing
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PLoS ONE: Bacteria that live inside and on mosquitoes
Time of Update: 2022-12-30
The first-of-its-kind study, published in the journal PLoS General, looked at the outer surface and internal microbiota of mosquitoes found in homes in Côte d'Ivoire, Africa.
The first-of-its-kind study, published in the journal PLoS General, looked at the outer surface and internal microbiota of mosquitoes found in homes in Côte d'Ivoire, Africa.
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A new genetic mechanism associated with severe childhood obesity
Time of Update: 2022-12-30
(End) Beijing, Dec. 20 (Zhongxin.
(End) Beijing, Dec. 20 (Zhongxin.
(End) Beijing, Dec. 20 (Zhongxin.
(End) Beijing, Dec. 20 (Zhongxin.
(End) Beijing, Dec. 20 (Zhongxin.
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New findings in immune cells could improve vaccine design
Time of Update: 2022-12-30
tissue-resident memory T cells are the primary responders to secondary infection Little is still known about the immune system's ability to remember disease-causing bacteria that have been defeated and avoid repeated infections, but a new study published in the journal Science Immunology clarifies an important aspect of the problem.
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Cancer Research reduces the risk of metastatic cancer by 72%
Time of Update: 2022-12-30
The researchers found that high-intensity aerobic exercise increased the consumption of glucose (sugar) by internal organs, reducing the amount of energy available to the tumor.
The researchers found that high-intensity aerobic exercise increased the consumption of glucose (sugar) by internal organs, reducing the amount of energy available to the tumor.
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The Lancet: BA.1, BA.4, BA.5 and Q.1.1 are resistant to all therapeutic antibodies
Time of Update: 2022-12-30
1. 1 resistance to monoclonal antibodies Are currently approved antibody therapies for the treatment of patients at high risk of severe COVID-19 disease also effective against virus variants currently circulating?
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Cover article: Identification of cell-specific markers of skeletal muscle aging
Time of Update: 2022-12-30
"Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence Monnuclear sequencing revealed 7 unique cell types and differences in gene expression with age.
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Artificial proteins catalyze the formation of stable quantum dots at room temperature
Time of Update: 2022-12-30
Or lead to a more sustainable way to manufacture nanomaterialsScience and Technology Daily News (Reporter Liu Xia) Researchers at Princeton University in the United States published a paper in the la
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Texas Biomedical – Frontier of biomedical research and development for Ebola virus in Sudan
Time of Update: 2022-12-30
"Only a few laboratories are able to conduct the regulated and specialized studies required by the FDA to support the approval of vaccines or treatments for these types of pathogens," explained Dr. Ricardo Carrion, head of the Texas Biomedical Company's Maximum Containment Contract Research Unit.
