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WHO's latest Nature paper: The number of new crown deaths is grossly underestimated, and the actual number may be 3 times as many as reported
Time of Update: 2022-12-30
According to the WHO's assessment of excess deaths, 25 countries – India, Russia, Indonesia, the United States, Brazil, Mexico, Peru, Turkey, Egypt, South Africa, Iran, Pakistan, Ukraine, Nigeria, the Philippines, Colombia, Italy, Poland, the United Kingdom, Bangladesh, Germany, Congo (Brazzaville), Romania, Spain and Ethiopia – had the highest number of excess deaths in 2020 and 2021.
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Two studies in Science found that starvation leads to cell remodeling
Time of Update: 2022-12-30
However, in the cells of XLCNM patients, no reduction in the site of contact occurs: the endosomes exert a "pull" on the endoplasmic reticulum, resulting in stabilization of the peripheral tubules and fenestration of the membrane-wrapped capsule.
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New tools offer hope in the fight against plant extinction
Time of Update: 2022-12-30
Analysis using national Red List data, as described in this study, not only helps to include more species diversity, but also provides insight into each country's unique conservation context.
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Nature unlocks the secret of a good night's sleep
Time of Update: 2022-12-30
"Our results show that there is a signaling pathway in brain cells from LKB1 to SIK3 and then to HDAC4," said Professor Masashi Yanagisawa, co-senior author of the study.
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Newly discovered protease inhibitors help in potato cultivation without inhibition
Time of Update: 2022-12-30
essayProtease Inhibitors from Solanum chacoense Inhibit Pectobacterium Virulence by Reducing Bacterial Protease Activity and Motility Image: Part of Figure 4 from the authors' study, depicting the protease and viability inhibition and cell morphological effects of M6 potato protein on Pectobacterium brasiliense Pb1692 in Brazil (top), and the study's two authors: first author Janak R.
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Science Immunology reveals the true face of this protein: evolutionary alarm molecules that drive inflammation
Time of Update: 2022-12-30
Now, scientists at Trinity College Dublin's Smurfit Institute of Genetics, led by Smurfit Professor of Genetics Seamus Martin, have discovered that interleukin-37 has unexpected functions as an immune-activating molecule, as previous studies have shown that this interleukin, instead acts as an "off switch" for the immune system.
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Baylor Chemical researchers synthesized new breakthrough compounds
Time of Update: 2022-12-30
, Associate Professor of Chemistry at Wacobaylor University, TexasCreating new synthetic compounds is often a complex, multi-step process that can take years of research.
, Associate Professor of Chemistry at Wacobaylor University, TexasCreating new synthetic compounds is often a complex, multi-step process that can take years of research.
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The first large-scale analysis of repeat amplification in the cancer genome is expected to reveal therapeutic targets
Time of Update: 2022-12-30
"The researchers believe that from the current results, similar analyses have the potential to find repeat amplifications that can be targets from other cancer types.
"The researchers believe that from the current results, similar analyses have the potential to find repeat amplifications that can be targets from other cancer types.
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Cell Stem Cell's specific stem cells can regenerate rotator cuff injuries
Time of Update: 2022-12-30
" ”A mineralizing pool of Gli1-expressing progenitors builds the tendon enthesis and demonstrates therapeutic potential If torn, the paper-thin tissue that connects the tendon to the bone (tendon end) does not heal on its own, limiting the success of surgical repair of the torn shoulder and knee tendons.
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Professor Xie Yuntao's team published a contralateral breast cancer risk prediction model for BRCA mutation patients in JCO
Time of Update: 2022-12-30
On December 8, 2022, the team of Professor Xie Yuntao of Peking University Cancer Hospital was published in the internationally renowned Journal of Clinical Oncology Published online titled "BRCA-CRisk: A contralateral breast cancer risk prediction model for BRCA carriers.
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Nature: Shocked! Certain gut bacteria can actually increase motivation and performance
Time of Update: 2022-12-30
They traced this effect back to the small molecules called metabolites produced by these gut bacteria--- which stimulate sensory nerves in the gut, thereby enhancing the activity of brain regions that control motivation during exercise.
com)Resources:Lenka Dohnalová et al.
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The new model highlights the importance of virus size in SARS-CoV-2 replication
Time of Update: 2022-12-30
Mechanics of diffusion-mediated budding and implications for virus replication and infection Dr. Mattia Bacca is an assistant professor at the University of British ColumbiaAs the world recovers from the economic and social impact of COVID-19, researchers such as Mattia Bacca continue to study SARS-CoV-2 and related viruses in order to better prepare for future pandemics.
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The new combination of drugs holds promise for improved treatment of cervical cancer
Time of Update: 2022-12-30
A study led by the University of Texas Southwestern Medical Center has shown that a new combination of drugs slows the growth of cancer cells through an unexpected mechanism, which promises to improve the treatment of cervical cancer.
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Inhibits tumor neogenesis RNA
Time of Update: 2022-12-30
Although the use of these RNA polymerase inhibitors in a clinical setting still has a long way to go, clinical trials are currently underway based on this enzyme for the treatment of cancer", explains lead researcher Daniel Gómez-Cabello.
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The full text of the Human Phenotypic Group Research Progress Report 2021 was officially released
Time of Update: 2022-12-30
The "Human Phenome Research Progress Report 2021" jointly compiled by the Chinese Phenotypic Group Research Collaboration Group, the International Human Phenotype Group Research Collaboration Group, the "Belt and Road" Human Phenotype Group Joint Research Center, the Shanghai International Human Phenotype Group Research Institute, the Human Phenotype Group Research Institute of Fudan University, and the Strategic Intelligence Research Department of the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences was officially released.
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The most popular Science news of 2022
Time of Update: 2022-12-30
Researchers have conducted a crazy study of the fruit's complex ancestorsBreeding helped remove the seeds of wild bananas, creating the fleshy fruit cherished today, a seemingly simple fruit with a surprisingly complex genetic history.
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New progress has been made in the regulation pathway and mechanism of soil phosphorus cycle function in karst farmland
Time of Update: 2022-12-30
In the southwest karst region, the traditional farmland nutrient management measures using chemical fertilizer are the most common means to maintain soil phosphorus supply, but the high calcium, magn
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Scientists have created a compound that can reverse the effects of potentially lethal drugs
Time of Update: 2022-12-30
Lead author Lyle Isaacs, a professor in the Department of Chemistry and Biochemistry at the University of Maryland, said, "Opioids already have a reversal agent in naloxone, but there are also various non-opioid abuses such as methamphetamine, PCP, methoxyephedrone, ecstasy (MDMA) and cocaine, which have no specific antidote.
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A novel ribosomes (RibosomeST) in spermatogenesis are capable of producing sperm-specific proteomes
Time of Update: 2022-12-30
On December 14, 2022, the team of Sha Jiahao and Guo Xuejiang of Nanjing Medical University and the team of Qin Yan of the Institute of Biophysics of the Chinese Academy of Sciences published the article "A male germ-cell-specific ribosome controls male fertility" in Nature, and found that the novel ribosomeST in spermatogenesis can produce sperm-specific 。Ribosomes are direct 20~30nm near-spheroids, and a wide range of ribosomes can be seen in high-resolution imaging of cells (Figure 2).
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Primate-specific genes are involved in the cell cycle processes of the brain in cancer and embryonic stages
Time of Update: 2022-12-30
The Daniel Zhang research group and collaborators of the Institute of Zoology, Chinese Academy of Sciences explored the above questions by integrating data from The Cancer Genome Atlas (TCGA), brain development transcriptome [10] and primate-specific gene collection [11], and the relevant results were published in Genome Biology (GB) on December 6, 2022, with the paper "Pan-cancer surveys indicate cell.
