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Rottecept for injection is approved for marketing, bringing a new treatment option for thalassemia patients
Time of Update: 2022-03-08
Public information shows that the approval of rotacept for injection will bring a new treatment option for adult patients with β-thalassemia, which is expected to reduce the burden of blood transfusion in patients with transfusion-dependent β-thalassemia and reduce the iron overload caused by blood transfusion.
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A new mechanism related to learning and memory - "mental retardation protein"
Time of Update: 2022-03-08
For example, FMRP, the deletion of a protein that causes Fragile X syndrome, intellectual disability and some forms of autism, has been shown to play a key role in these brain functions, helping to regulate the synaptic connections between neurons .
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Nature sub-journal: Researchers use sound to control mammalian cells for the first time
Time of Update: 2022-03-08
"To test whether the channel could activate other types of cells in response to ultrasound, the team used a gene therapy approach that added the gene for human TRPA1 to a specific set of neurons in the brains of living mice .
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Wang Jianwei's team from Tsinghua University School of Pharmacy has made new progress in the research direction of hematopoietic stem cell function regulation
Time of Update: 2022-03-08
1. Research background 2.
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India's new vaccine can fight six coronaviruses
Time of Update: 2022-03-08
"In this study, we used an immunoinformatics approach to design 'AbhiSCoVac', a multi-epitope, multi-target chimeric peptide that can Protective immunity against 6 strongly pathogenic members of the coronavirus family, including 2019-nCoV, SARS-CoV and MERS-CoV .
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The repeated inhalation vaccine for the global epidemic is expected to become a powerful tool for the prevention and control of Omicron
Time of Update: 2022-03-08
The level of antibodies will gradually decline, which means that the immune effect of the vaccine will be weakened, and the new characteristics (high immune escape, infection of the upper respiratory tract) produced by the mutation of strains such as Omicron, so after large-scale vaccination, vaccination with new crown Vaccine booster shots have become a widely promoted policy around the world .
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The genome of the giant tiger-headed manatee has been deciphered, and the cause of human ichthyosis has also been found
Time of Update: 2022-03-08
"The most surprising result of our investigation was that we figured out why this sea giant has a bark-like skin," said Diane Le Duque from the Institute of Human Genetics at Leipzig University Hospital .
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Shanghai Jiaotong University Deng Zixin's team reveals the catalytic cycle trajectory of dimerized non-ribosomal peptide synthases
Time of Update: 2022-03-08
Recently, the team of Professor Zixin Deng from the School of Life Science and Technology of Shanghai Jiao Tong University and the State Key Laboratory of Microbial Metabolism published in the journal Nature Communications entitled "Epimerase-embedded dimerization of non-ribosomal peptide synthases.
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Ji Guangju's group reveals the important role of ERp44 in the development of mouse cardiac intimal cushion
Time of Update: 2022-03-08
On January 28, 2022, the research group of Ji Guangju from the Institute of Biophysics, Chinese Academy of Sciences published a research result entitled "ERp44 is required for endocardial cushion development by regulating VEGFA secretion in myocardium" online in " Cell Proliferation " .
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Your microbiome shapes your life, but where does it come from?
Time of Update: 2022-03-07
Although many researchers have studied microbial community composition in natural populations, few have attempted to use controlled environments to uncover the processes by which new species successfully join the gut microbial ecosystem .
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Patients with positive Phase 2 clinical results of Regeneron Wet AMD Therapy improved multiple disease markers
Time of Update: 2022-03-07
On February 11, 2022, Regeneron Pharmaceuticals announced positive results from a proof-of-concept Phase 2 clinical trial of aflibercept in wet age-related macular degeneration (AMD) .
References:[1] Regeneron Presents Encouraging Phase 2 Results For High-Dose Aflibercept 8 Mg In Wet Age-Related Macular Degeneration At Angiogenesis Meeting.
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New wearable device helps prosthetic hands achieve 'grasping' freedom
Time of Update: 2022-03-07
S. researchers say they have pioneered a wearable, multi-channel haptic feedback soft robotic armband that conveys artificial touch to the robotic user, allowing them to dexterously use a prosthetic hand while grasping and moving two objects without breaking or falling, even if their view of both objects is obstructed .
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Science challenges conventional wisdom: How calorie restriction affects the body
Time of Update: 2022-03-07
In a group of CALERIE participants on a calorie-restricted diet, their thymus was "rejuvenated," Dixit said: MRI scans showed increased thymus mass and volume compared to the start of the study, increased levels of CD8 T cells Generation is also increased .
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Attention Cell!
Time of Update: 2022-03-07
jpg"/>            A study by researchers at Stanford University School of Medicine shows that antibodies produced by the new coronavirus vaccine are better at recognizing virus mutations than antibodies produced by natural infection .
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Chemotherapy or no chemotherapy?
Time of Update: 2022-03-07
For individual patients in particular, these results suggest caution in the use of gene expression tests .
Comparative analysis of molecular signatures reveals a hybrid approach in breast cancer: Combining the Nottingham Prognostic Index with gene expressions into a hybrid signature .
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One stone kills many birds—Professor Wang Jianxin’s team developed a multifunctional ginsenoside nano-formulation that inhibits lung metastasis of triple-negative breast cancer
Time of Update: 2022-03-07
Wang Jianxin's research group from the School of Pharmacy, Fudan University published a research result entitled "Versatile ginsenoside Rg3 liposomes inhibit tumor metastasis by capturing circulating tumor cells and destroying metastatic niches" in Science Advances on February 11, 2022 , designed a simple and efficient novel multifunctional ginsenoside liposome, which can target and capture CTCs while destroying the metastatic microenvironment of cancer cells, thereby achieving a significant effect of inhibiting lung metastasis of triple-negative breast cancer .
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DNA testing exposes tactics of international criminal networks to sell ivory
Time of Update: 2022-03-07
Uncovering links between ivory seizures in African and Asian ports could provide more evidence for those caught poaching elephants and smuggling ivory, and strengthen the prosecution of responsible transnational criminal organizations, the study said said lead author Samuel Wasser, a professor of biology at the University of Washington and director of the Center for Environmental Forensic Science, where the team developed the genetic tools behind the work .
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Boosting immune defenses: Interleukin-2 promotes CD8 T cell fate determination
Time of Update: 2022-03-07
Understanding the details of how naïve immune cells develop into effective infection-resistant or long-term memory cells is important because it can help us understand which components of a complex response are necessary to provide protection against infection or cancer .
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Nature Biotechnology: Streamlining RNA Editing to Treat Genetic Diseases
Time of Update: 2022-03-07
What's special about this technology is that it effectively uses RNA-editing enzymes that are naturally present in human cells .
"To overcome these problems, Mali and his colleagues engineered a new guide RNA that is highly efficient at recruiting the cell's own ADARs to edit precise target RNA regions .
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In addition to taking regular medication to treat high blood pressure, a healthy lifestyle is required
Time of Update: 2022-03-07
Screenshot source: JAMA Network OpenBased on the Dongfeng-Tongji cohort of the School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, this study included a total of 14,392 hypertensive patients with an average follow-up of 7.
