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The new treatment can significantly improve the efficacy of chemotherapy for breast cancer and prevent metastasis
Time of Update: 2023-01-06
Nature Communications, 2022; 13 (1) A new treatment developed by Tel Aviv University could significantly improve chemotherapy in breast cancer patients, reducing the risk of lung metastases after chemotherapy from 52 percent to just 6 percent.
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The sense of smell affects the causes of obesity
Time of Update: 2023-01-06
From there, the scientists used the same two groups of mice to see how the smell of food or the visual stimuli of food affected the distribution of body fat during fasting.
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Professor Mo Wei's team revealed that microglia sense amyloid plaque hardness through Piezo1 to limit the progression of Alzheimer's disease
Time of Update: 2023-01-06
Alzheimer's disease (AD) is the most common neurodegenerative disease in older people, characterized by progressive cognitive impairment and behavioral impairment. The two typical pathological featur
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Scientists have discovered a molecule that can help treat Parkinson's
Time of Update: 2023-01-06
Image: Dr. Tianyi Mao (left) and Dr. Haining Zhong (left), scientists at the Vollum Institute at Oregon Health and Science University, led a new study that found that adenosine effectively inhibits dopamine in the brain.
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Nature Communications: Wang Jing/Mao Kangshan/Liu Jianquan's research group collaborates to reveal the genetic mechanism of environmental adaptation of forest tree species and future climate change...
Time of Update: 2023-01-06
With the intensification of the greenhouse effect and increasingly severe climatic conditions, climate change has posed a serious threat to biodiversity and the stability of natural ecosystems. As th
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Peng's lab published papers at CELLS
Time of Update: 2023-01-06
3390/cells11203290Published: OCT 2022Document type: ArticleAttachment: Full text link ：Unraveling Differential Transcriptomes and Cell Types in Zebrafish Larvae Intestine and Liver（IF=7.
3390/cells11203290Published: OCT 2022Document type: ArticleAttachment: Full text link ：Unraveling Differential Transcriptomes and Cell Types in Zebrafish Larvae Intestine and Liver（IF=7.
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Brain changes: the ongoing effects of COVID-19
Time of Update: 2023-01-06
(Marco Aurelio Romano-Silva, Federal University of Minas Gerais)Through MRI, the scientists found that sensorimotor brain regions in children who contracted COVID-19 a few months ago now show a higher demand for resources.
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Nature reports a previously completely unknown new target for Alzheimer's treatment
Time of Update: 2023-01-06
We were able to demonstrate that medin significantly enhances pathological changes in blood vessels in Alzheimer's patients," said Dr. Jonas Neher, who led the study.
We were able to demonstrate that medin significantly enhances pathological changes in blood vessels in Alzheimer's patients," said Dr. Jonas Neher, who led the study.
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FMRP mediates immune evasion of mouse tumors
Time of Update: 2023-01-06
essayAberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion The researchers reported that gene inactivation of neural fragility X intellectual disability protein (FMRP) in cancer cells led to reduced growth and increased vulnerability of T cells in mouse tumors.
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Tuberculosis that "eats bones"
Time of Update: 2023-01-06
”An Ancestral Mycobacterial Effector Promotes Dissemination of Infection Tuberculosis is usually a lung disease, but it can also be found in bones in 2% of cases in the United States.
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The researchers demonstrated how to trigger the release of pathogens with music
Time of Update: 2023-01-06
Senior co-author Mohammad Al Faruque, professor of electrical engineering and computer science at UCI, said: "People can play a piece of music on a smartphone, or on a TV or other audio device in or near a negative pressure room.
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Structural and functional mechanisms by which bacteria activate SspE through DNA vulcanization modification to resist phage infestation
Time of Update: 2023-01-06
Recently, the team of Professor Wu Geng from the School of Life Science and Technology/State Key Laboratory of Microbial Metabolism of Shanghai Jiao Tong University, together with the team of Professor Wang Lianrong and Professor Chen Shi of Wuhan University, elucidated the structural and functional mechanism of bacteria such as Streptomyces and other bacteria activating the nuclease activity of SspE protein in bacteria through phosphorsulphylation modification on DNA, and eliminating the phage DNA that invaded bacteria, thereby resisting phage infection.
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Structural and functional mechanisms by which bacteria activate SspE through DNA vulcanization modification to resist phage infestation
Time of Update: 2023-01-06
Recently, the team of Professor Wu Geng from the School of Life Science and Technology/State Key Laboratory of Microbial Metabolism of Shanghai Jiao Tong University, together with the team of Professor Wang Lianrong and Professor Chen Shi of Wuhan University, elucidated the structural and functional mechanism of bacteria such as Streptomyces and other bacteria activating the nuclease activity of SspE protein in bacteria through phosphorsulphylation modification on DNA, and eliminating the phage DNA that invaded bacteria, thereby resisting phage infection.
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Professor Shen Pingping's team from Nanjing University has made new progress in the field of PPAR?post-translational modification to regulate cellular metabolic reprogramming mechanism
Time of Update: 2023-01-06
The research work was supported by the National Key R&D Program of the Ministry of Science and Technology "Protein Machinery and Life Process Regulation" (2017YFA0506000) and the Guangdong Provincial Basic and Applied Basic Research Fund Regional Joint Fund Project (Key Project) (2021B1515120016。 Currently, the research results are titled "Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions", 2022 Published online on November 3 in Cell death & Differentiation.
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Cell Reports article explains how HIV-1 evades the immune system
Time of Update: 2023-01-06
If antibodies are so effective, then why do they seem to not work?A new study led by the University of Montreal in Canada shows for the first time that in humanized mice, the expression of the viral protein Vpu is critical for infected cells to evade the ADCC clearance mechanism.
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Brain organoids reveal in detail the dangers of drinking alcohol during pregnancy
Time of Update: 2023-01-06
In a new study, published Nov. 16, 2022, in Molecular Psychiatry, researchers at the University of California San Diego School of Medicine used human brain organoids to more specifically document how alcohol exposure impairs the development and function of new brain cells.
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WDR47 and Camsap are involved in the molecular mechanisms that regulate the formation of central microtubules in kinesciliae
Time of Update: 2023-01-06
Kinesilia are microtubule-based accessory structures on the surface of eukaryotic cells, which are widely distributed in tissues and organs such as trachea, ventricles and fallopian tubes. Through pe
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The first data review suggests that taking probiotics along with prescription antibiotics can reduce damage to the gut microbiome
Time of Update: 2023-01-06
”Effect of adding probiotics to an antibiotic intervention on the human gut microbial diversity and composition: A systematic review Probiotics reduce the changes in the human gut microbiota caused by some antibiotics.
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Chronic jet lag has been detected in people living with HIV
Time of Update: 2023-01-06
"Delayed circadian rhythms in older Africans living with human immunodeficiency virus (HIV) According to the latest findings from researchers from universities in South Africa and the United Kingdom, the body clock in people living with HIV is significantly delayed, consistent with the symptoms of jet lag.
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Science: A previously unknown, common mechanism by which cancer cells shut down the anti-cancer immune response
Time of Update: 2023-01-06
Original:Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion Douglas HanahanImage source: Ludwig Cancer Research CenterA study by the Ludwig Cancer Research Center found that a single protein was expressed in high amounts in cancer cells with multiple malignancies, establishing a multilayer barrier for the anti-cancer immune response in mouse cancer models, thereby protecting tumors from immune detection and destruction.
