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Chinese Journal of Neurosurgery: An analysis of intracranial primary multiple Rosai-Dorfman disease
Time of Update: 2022-10-19
Fig. 1 Preoperative enhanced head MRI showed multiple flattened occlusive masses in the left occipital lobe and right frontal lobe, the base was located in the dura, and the surrounding brain tissue was compressed.
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Classification and differential diagnosis of impaired consciousness
Time of Update: 2022-10-19
Consciousness disorder refers to a pathological process that cannot correctly understand its own state and/or objective environment and cannot respond correctly to environmental stimuli, and its pathological basis is the dysfunction of the cerebral cortex, thalamus and brainstem reticular system.
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JNNP: Validation of MATCH scores, a predictive tool for identifying patients with KELCH-like protein-11 antibodies
Time of Update: 2022-10-19
The MATCH score is a comprehensive scoring system based on clinical features and cancer relevance to identify patients who should be tested for KLHL11 IgG.
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【One case per day】Ankylosing spondylitis
Time of Update: 2022-10-19
Beginning in the sacroiliac joint, early destruction, space narrowing and subchondral osteosclerosis, upward invasion of the lumbar spine, thoracic spine, cervical spine is rare, ligaments including anterior longitudinal ligament, flavum ligament, joints and tendons are prone to calcification and ossification.
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【PHILIPS daily case】Blake cyst teaching case
Time of Update: 2022-10-19
The classic imaging of the Blake cyst is a cyst filled with cerebrospinal fluid (white arrow in the figure) visible posterior to the lower part of the cerebellar vermise of the posterior fossa (yellow arrow in the figure), which is separated from the cerebellar medullary cistern (red arrow in the figure).
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【Reading notes】Arachnoid cyst
Time of Update: 2022-10-19
MRI findings: T1, T2, FLAIR are manifested as intracranial extracerebral fluid accumulation, consistent with cerebrospinal fluid signal, clear boundaries, T2* no "flowering sign" (except when combined with hemorrhage), DWI is not diffuse limited, no strengthening after enhancement, MRA can show cortical vascular displacement away from the skull, MRV can show abnormal venous return (in the case of large cysts).
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After the extracerebral space is widened, how can I tell if it is cerebral atrophy or subdural effusion?
Time of Update: 2022-10-19
【Brain atrophy】 Etiology: Cerebral atrophy is a decrease in the volume and number of brain tissue cells caused by various factors, secondary enlargement of the ventricles and subarachnoid space, which
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Neurology: Relationship between cerebrovascular and Alzheimer's disease biomarkers and cholinergic white matter degeneration in cognitively impaired patients
Time of Update: 2022-10-19
Figure 1: Cover image of the paperRecent studies based on diffusion tensor imaging (DTI) examine these pathways, providing an opportunity to study the integrity of the cholinergic system and its potential links to cognitive performance and pathophysiological processes in vivo.
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Neurology: The relationship between the prevalence of multiple sclerosis and sociodemographic, health system and lifestyle factors in countries and regions
Time of Update: 2022-10-19
Discussion: The strong correlation between per capita health expenditure and the national prevalence of multiple sclerosis suggests that the theory that differences in multiple sclerosis prevalence are primarily attributable to the latitudinal effect on vitamin D is incomplete.
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2022ECNP: Cognitive effects of ketamine in SSRI-resistant depression in relation to 5-HT1B receptor binding
Time of Update: 2022-10-19
In the ketamine group, there was no correlation between changes in cognitive test results and changes in 5-HT1B receptor bindingChanges in CPT after ketamine treatment are inversely proportional to 5-HT1B receptor binding in the hippocampus region at baselineAfter a single injection of racemic ketamine for the treatment of major depressive disorder for 24-72 hours, a positive effect on cognition was observed.
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Radiology: functional MRI imaging of healthy adults at rest
Time of Update: 2022-10-19
RSFMRI data from healthy participants in the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) database retrieved in this retrospective study (October 2010-September 2013) were used to generate CAP by applying single-volume temporal clustering 。 Spatial clustering is then performed to capture dynamic coactivation and deactivation within or between primary sensory networks and higher-order cognitive networks, including the default mode network [DMN], attention network [AN], and frontal network [FPN].
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Neurology: Relationship between cerebrovascular and Alzheimer's disease biomarkers and cholinergic white matter impairment in cognitively impaired patients
Time of Update: 2022-10-19
In summary, in the elderly without cognitive impairment, WMLs play a central role in the degeneration of cholinergic pathways.
elderly without cognitive impairment, WMLs play a central role in the degeneration of cholinergic pathways.
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Two common types of brain atrophy
Time of Update: 2022-10-19
Since the cerebellum is mainly involved in the regulation of somatic balance and muscle tone, patients with cerebellar atrophy often have symptoms such as gait instability, ataxia, and slurred speech.
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Euro Radio: Combining [18F]FDG-PET with MRI predicts the likelihood of postoperative seizure recurrence in patients with temporal lobe epilepsy
Time of Update: 2022-10-19
Combined [ 18 F]FDG-PET with MRI structural patterns in predicting post-surgical seizure outcomes in temporal lobe epilepsy patients.
Combined [ 18 F]FDG-PET with MRI structural patterns in predicting post-surgical seizure outcomes in temporal lobe epilepsy patients.
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AAV gene therapy for Krabbe disease is 100% effective
Time of Update: 2022-10-19
Forge Biologics recently announced the latest clinical data of its Phase 1/2 RESKUE for the treatment of Krabbe's disease in AAV gene therapy FBX-101 at the 29th Congress of the European Gene Therapy
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【One case per day】MRI diagnosis of intramedullary schwannoma was 1 case
Time of Update: 2022-10-19
Schwannoma originates from myelin Schwann cells, is the most common tumor in the spinal canal, accounting for 30% of spinal canal tumors, because the spinal cord does not contain myelin or Schwann cel
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One case of bilateral thalamic lesions
Time of Update: 2022-10-19
Case oneA 46-year-old man presents with worsening symptoms of progressive abdominal pain, vomiting, fever, and diffuse weakness.
Case oneA 46-year-old man presents with worsening symptoms of progressive abdominal pain, vomiting, fever, and diffuse weakness.
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Radiology: Application of choroidal plexus volume and permeability in the clinical spectrum of Alzheimer's disease in cranial MRI
Time of Update: 2022-10-19
0T cranial MRI, the choroid plexus (CP) volume was higher in the late stages of cognitive impairment, and changes in CP permeability were related to the severity of the disease.
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How to distinguish cerebral atrophy from subdural effusion
Time of Update: 2022-10-19
Cerebral atrophy: Etiology: Cerebral atrophy is a decrease in the volume and number of brain tissue cells caused by various factors, secondary to enlargement of the ventricles and subarachnoid space,
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Alzheimer & Dementia: In addition to seeing a doctor, there is also a cognitive disorder that is discovered by itself!
Time of Update: 2022-10-19
References:The use of subjective cognitive complaints for detecting mild cognitive impairment in older adults across cultural and linguistic groups: A comparison of the Cognitive Function Instrument to the Montreal Cognitive Assessment.
