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Treat chronic pain!
Time of Update: 2021-04-19
AbbVie participated in the Investment Biopharmaceutical Innovation Technology Conference (BPIT) which will be held on April 9-10, 2021 Shanghai kicked off, four major sub-venues, exciting (click to view focus topics).
Participants who successfully registered for the Shanghai 2021 BPIT conference will receive a limited edition of "CAR-T Cell Therapy Industry Research Report" 2021.
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Clinical manifestations of proximal intracranial posterior circulation syndrome|Knowledge Card
Time of Update: 2021-04-19
Posterior circulation ischemia (PCI) is a clinicopathological condition related to vertebrobasilar artery system infarction, mainly including the brain stem (48%) and the area dominated by the posterior inferior cerebellar artery (PICA) (36%).
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Express | Hope to benefit nearly one-tenth of school-age children, FDA approves the first non-stimulant hyperactivity treatment in ten years
Time of Update: 2021-04-19
▎The content team editor of WuXi AppTec recently, Supernus Pharmaceuticals announced that the US FDA has approved the company's Qelbree (viloxazine sustained-release capsules) to treat attention deficit hyperactivity disorder (ADHD) in pediatric patients aged 6-17.
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Cases Shenghui | Cerebral hemorrhage after thrombus removal in patients with ischemic stroke?
Time of Update: 2021-04-19
According to the "Chinese Guidelines for Endovascular Treatment of Acute Ischemic Stroke 2018" [8]: Within 6 hours of onset, mechanical thrombectomy is strongly recommended when the following criteria are met: pre-stroke mRS score of 0 to 1; ischemic stroke is caused by the internal carotid artery Or MCAM1 segment occlusion; age ≥ 18 years; NIHSS score ≥ 6 points; Alberta stroke project early CT score (ASPECTS score) ≥ 6 points (Class I recommendation, level A evidence).
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New painkillers!
Time of Update: 2021-04-19
com/fda/" target="_blank">the FDA ) Arthritis Joint Advisory Committee (JAAC) and Risk Management Advisory Committee and (DSRMAC) of monoclonal antibody drug safety class Results of the bioon.
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The latest research reveals that sugar can affect brain development. If you eat too much sugar when you are young, it will impair your future learning and memory abilities.
Time of Update: 2021-04-19
This study in the Journal of Translational Psychiatry also found that high-sugar diet impairs brain development and affects learning and memory.
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Compared with myocardial infarction, the risk of depression after cerebral infarction is higher
Time of Update: 2021-04-19
Naomi Mayman and others of Mount Sinai School of Medicine in the United States, based on the Medicare medical insurance database in the United States, explored American patients ≥65 years of age from July 1, 2016 to December 31, 2017, and compared ischemic stroke (IS) and Risks and predictors of new depression after myocardial infarction (MI).
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Nature | Clinical Trial Results of Vaccine Targeting IDH1 Mutant Glioma
Time of Update: 2021-04-19
This vaccine can induce specific and therapeutic helper T cell responses in humanized MHC mice to effectively inhibit IDH1.
Recently, the Michael Platten research group from the German Cancer Research Center published an article titled A vaccine targeting mutant IDH1 in newly diagnosed glioma in the journal Nature.
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A 4-year-old child has 8 abscesses in the brain?
Time of Update: 2021-04-19
Director Chen Ruoping recalled that during the head MRI, they found that there were 8 abscesses in the brain of the child.
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Clinical manifestations of mid-segment intracranial posterior circulation syndrome|Knowledge Card
Time of Update: 2021-04-19
Recommended reading↓↓↓Clinical manifestations of proximal intracranial circulation syndrome Table 1 Middle intracranial retrocirculation syndrome Note: PPRF: Parapontine midbrain reticular structure Yimaitong compiled from: Posterior circulation ischaemic stroke-a review part I: anatomy, aetiology and clinical presentations.
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Toothache is terrible!
Time of Update: 2021-04-19
Beijing time on March 27, published in the "Science Advances" in a new study, led by the University of Erlangen-Nuremberg, Germany, the Howard Hughes Medical Institute (HHMI) and Massachusetts General Hospital led the international After more than ten years, the research team finally clarified how the teeth perceive cold.
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Why inactive synapses are "annoying"? Scientists reveal the "punishment" mechanism of synapse pruning
Time of Update: 2021-04-19
Therefore, the researchers used the corpus callosum connection as a model for studying active synaptic pruning.
In order to further verify the importance of neuronal activity for axon pruning, the researchers further injected tetrodotoxin (TTX) to achieve overall inhibition of neurons in the corpus callosum brain area.
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Do you know the formula for calculating the volume of intracranial hematoma?
Time of Update: 2021-04-19
Our usual method is to use intracerebral and epidural hematoma hemorrhage (ml) = maximum slice length × width × layer spacing × number of lesion layers × 0.
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The long-term loneliness of middle-aged people exacerbates the risk of dementia. Short-term loneliness helps prevent dementia...
Time of Update: 2021-04-19
Recently, in a new study published in the Journal of the Alzheimer's Association "Alzheimer's & Dementia: The Journal of the Alzheimer's Association", a research team led by Professor Qiu Weiqiao from Boston University School of Medicine showed that middle-aged people continue to Loneliness can threaten brain health and increase the risk of dementia in the future.
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Nature: The new environment restarts neural circuits and promotes learning.
Time of Update: 2021-04-19
The authors of this study novelly reset the neural circuit connecting the ventral hippocampus (vHPC) and mPFC, and promoted the ability to overcome established strategies.
These results indicate that novel stimuli promote adaptive learning through the D1R-mediated vHPC-mPFC circuit, so that it is possible to learn the plasticity of related circuits for subsequent research.
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Nature Sub-Journal: Li Yulong’s team develops a new type of fluorescent probe to achieve accurate detection of dynamic changes in serotonin in vivo
Time of Update: 2021-04-19
On April 5, 2021, the Li Yulong Laboratory of Peking University published an online research paper titled: A genetically encoded sensor for measuring serotonin dynamics in the journal Nature Neuroscience, reporting the development and development of a new genetically encoded 5-HT fluorescent probe Successful application in a variety of model organisms.
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PNAS|Kong Eryan/Zhang Zhongjian's team reveals the pathogenic mechanism of GFAP palmitoylation in neurodegenerative diseases
Time of Update: 2021-04-19
Recently, the team of Xinxiang Medical College-Institute of Psychiatry and Neuromedicine Kong Eryan/Zhang Zhongjian, Liang Yinming’s team and Professor Gao Jian of Xuzhou Medical University jointly published the title "GFAP hyper-palmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice" on PNAS.
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New drug for glioblastoma!
Time of Update: 2021-04-19
: For Kazia's new anti-cancer drug paxalisib, Simcere Pharmaceuticals has obtained the development and Commercialization rights.
com/vitroDiagnostics/" target="_blank">diagnosed glioblastoma have not received any new drug treatments.
com/vitroDiagnostics/" target="_blank">diagnosisOriginal source: Kazia Licenses Rights to Paxalisib in Greater China to Simcere, a Leading Chinese Pharmaceutical Company
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Harvard study: Spanking or more serious forms of violence affect children's brain development
Time of Update: 2021-04-18
Today, a Harvard University research team published a study in Child Development showing that spanking may be a more serious form of violence that affects children’s brain development.
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Orthostatic dizziness/vertigo diagnosis and treatment, just read this!
Time of Update: 2021-04-18
HOD/V is common in orthostatic hypotension (OH) and postural tachycardia syndrome (POST), as well as hypovolemia, anemia, autonomic nervous disease, bilateral vestibular disease, peripheral neuropathy, and benign paroxysmal positional vertigo , Persistent posture-perceptual dizziness and heart disease, etc.
