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Every year, 795,000 Americans experience new or recurring strokes, resulting in a population prevalence rate of 2.
9%.
Of these patients, about one-third will suffer from post-stroke depression (PSD), which is related to worse functional outcomes, lower quality of life, and higher mortality.
At present, the exact cause of PSD is still unclear.
Whether PSD represents a psychological response to a life-changing medical event or a biological change after cerebral ischemia is still controversial.
Although research on PSD has been conducted for decades, due to many factors, including variable or outdated evaluation of depression, inconsistent inclusion and exclusion criteria, small sample size, and single-center recruitment, the risk factors are still controversial.
In addition, many studies have occurred outside the United States, which may limit the generalizability to the American population.
Whether PSD is different from depression after other ischemic vascular events, and how much PSD is just a continuation of existing depression is still unclear.
Naomi Mayman and others of Mount Sinai School of Medicine in the United States, based on the Medicare medical insurance database in the United States, explored American patients ≥65 years of age from July 1, 2016 to December 31, 2017, and compared ischemic stroke (IS) and Risks and predictors of new depression after myocardial infarction (MI).
They found that during the 1.
5-year follow-up, stroke patients (n=174,901) were 50% more likely to suffer from depression than MI patients (n=193,418).
Anxiety history is the strongest predictor of PSD, and being discharged home is the most protective, that is, it is not prone to depression.
Female patients, Caucasian patients, and patients younger than 75 years of age are more likely to be diagnosed with post-stroke depression.
This data study of nearly 200,000 people shows that despite the similarities between MI and stroke, the incidence of PSD is very high.
There are several predictors of post-stroke depression, the most significant being a history of anxiety.
The results of this study provide credibility for the process of stroke leading to depression and further emphasize the need for consistent depression screening for all stroke patients.
Original Source: Risk and Predictors of Depression Following Acute Ischemic Stroke in the Elderly Naomi Mayman, Laura Katherine Stein, John Erdman, Alana Kornspun, Stanley Tuhrim, Nathalie Jette, Mandip DhamoonNeurology Mar 2021, 10.
1212/WNL.
0000000000011828;DOI: 10.
1212/WNL.
0000000000011828;DOI: 10.
1212/WNL.
0000000000011828; .
0000000000011828
9%.
Of these patients, about one-third will suffer from post-stroke depression (PSD), which is related to worse functional outcomes, lower quality of life, and higher mortality.
At present, the exact cause of PSD is still unclear.
Whether PSD represents a psychological response to a life-changing medical event or a biological change after cerebral ischemia is still controversial.
Although research on PSD has been conducted for decades, due to many factors, including variable or outdated evaluation of depression, inconsistent inclusion and exclusion criteria, small sample size, and single-center recruitment, the risk factors are still controversial.
In addition, many studies have occurred outside the United States, which may limit the generalizability to the American population.
Whether PSD is different from depression after other ischemic vascular events, and how much PSD is just a continuation of existing depression is still unclear.
Naomi Mayman and others of Mount Sinai School of Medicine in the United States, based on the Medicare medical insurance database in the United States, explored American patients ≥65 years of age from July 1, 2016 to December 31, 2017, and compared ischemic stroke (IS) and Risks and predictors of new depression after myocardial infarction (MI).
They found that during the 1.
5-year follow-up, stroke patients (n=174,901) were 50% more likely to suffer from depression than MI patients (n=193,418).
Anxiety history is the strongest predictor of PSD, and being discharged home is the most protective, that is, it is not prone to depression.
Female patients, Caucasian patients, and patients younger than 75 years of age are more likely to be diagnosed with post-stroke depression.
This data study of nearly 200,000 people shows that despite the similarities between MI and stroke, the incidence of PSD is very high.
There are several predictors of post-stroke depression, the most significant being a history of anxiety.
The results of this study provide credibility for the process of stroke leading to depression and further emphasize the need for consistent depression screening for all stroke patients.
Original Source: Risk and Predictors of Depression Following Acute Ischemic Stroke in the Elderly Naomi Mayman, Laura Katherine Stein, John Erdman, Alana Kornspun, Stanley Tuhrim, Nathalie Jette, Mandip DhamoonNeurology Mar 2021, 10.
1212/WNL.
0000000000011828;DOI: 10.
1212/WNL.
0000000000011828;DOI: 10.
1212/WNL.
0000000000011828; .
0000000000011828
