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The first Parkinson's cell therapy of its kind!
Time of Update: 2022-02-21
54% On January 24, Boji Pharmaceutical released the 2021 annual performance forecast, and the annual net profit attributable to shareholders of listed companies is expected to be 37 million to 48 million yuan, a year-on-year increase of 117.
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Indicators of neurological diseases - biomarkers
Time of Update: 2022-02-21
In the field of neurology, biomarkers are mainly used in the diagnosis of diseases, prognostic analysis, prediction of treatment response and detection of adverse reactions, etc.
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New progress of central nervous system infectious diseases in 2021, one article inventory
Time of Update: 2022-02-21
(3) Professor Fuhua Peng introduced that cryptococcal infection-related encephalitis syndrome has encountered more than 60 cases of non-HIV cryptococcal meningitis patients in his hospital, usually 2-3 times the lumbar puncture review was negative for Cryptococcus, and suddenly new cases appeared.
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Why do people need good sleep?
Time of Update: 2022-02-21
Figure 4: Study title The study is based on poor sleep quality and less sleep duration affecting more than half of older adults in Canada and is associated with adverse health outcomes, in the context of high rates of multiple chronic diseases and shortened lifespans .
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These people never feel full, the problem is in their cerebellum
Time of Update: 2022-02-21
The results of the analysis showed that, in the same brain region that Chen's team found in mice, the brain region of Prader-Willi syndrome patients, the aDCN, showed significant neural activity compared to healthy people.
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Gene therapy for Parkinson's disease
Time of Update: 2022-02-21
Glial cell-derived neurotrophic factor (GDNF) is a protein with nerve repair and neuroprotection, which can regenerate some degenerated neurons to a certain extent, and has potential therapeutic value in a variety of neurological diseases .
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MRI performance in different periods of cerebral hemorrhage, a must for beginners!
Time of Update: 2022-02-21
Although the hematoma contains the same substance, after the red blood cells rupture and dissolve, the hematoma becomes a low-protein hematoma fluid, and T2 can change from the previous low signal to high signal, which can help us better understand the subacute phase of cerebral hemorrhage.
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Sunflower syndrome: a rare photosensitive epilepsy
Time of Update: 2022-02-21
Historical cases have documented stereotyped hand waving in the presence of light in epilepsy patients, describing the behavior as self-induced seizures by simulating the stroboscopic effect .
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【News】AI helps rare disease research!
Time of Update: 2022-02-21
Under the 20-week partnership, the parties will use Insilico's powerful AI target discovery platform, PandaOmics, to analyze Gentogene's rare disease database, patient data from multi-omics analyses, and NPC cell lines to identify cellular differences Metabolites, pathways and modifier genes .
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Can wolfberry soaking in water in a vacuum cup prevent dementia?
Time of Update: 2022-02-21
Using an AD transgenic nematode model, Chang Chen's group from the Institute of Biophysics, Chinese Academy of Sciences found that lycium barbarum extract (LBE) inhibited the development of Alzheimer's disease by activating the antioxidant system and mitochondrial unfolded protein response (mtUPR).
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Science Large longitudinal sample reveals association of Epstein-Barr virus infection with multiple sclerosis
Time of Update: 2022-02-21
To further explore whether immune dysregulation in the preclinical stage can increase viral susceptibility, the authors randomly selected 30 MS patients and 30 corresponding controls, and collected serum samples before and after MS onset .
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JPD: How are idiopathic REM sleep behavior disorder, cardiovascular risk factors, and synaptopathies related?
Time of Update: 2022-02-20
They assessed in a prospective cohort (Montreal-iRBD) study whether cardiovascular disease and metabolic risk factors alter the speed of appearance transition from idiopathic/isolated rapid eye movement sleep behavior disorder (iRBD) to Parkinson's disease or dementia or type .
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Rabies encephalitis, listeria encephalitis, familial Fahr disease with cerebral hemorrhage 3-minute film reading 40 issues
Time of Update: 2022-02-20
The imaging manifestations of HDLS include: bilateral frontal and fronto-parietal white matter T2/FLAIR hyperintensity, T1 hypointensity, early asymmetric manifestations of patchy or localized lesions, mostly non-enhancing, DWI signal may increase , some cases of CT scan showed spot-like calcifications in the lesion area - bilateral lateral ventricle body and central semiovale area DWI persistent high signal (relatively characteristic changes) .
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Movement disorder: Are people with restless legs at higher risk for depression and suicide?
Time of Update: 2022-02-20
Manage Prevention Hereby, Université de Montpellier, France, et al, (1) compared the frequency of depressive symptoms and suicidal thoughts in RLS patients and controls, quantified using the Baker Depression Scale-II (BDIII) ; Psychiatric interviewing (MINI) to assess current MDE frequency and suicide risk in a subgroup of RLS patients .
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Eat more dark green vegetables to relieve headaches?
Time of Update: 2022-02-20
Recently, researchers from Stony Brook University and the University of Pennsylvania found that an anti-inflammatory diet rich in dark green leafy vegetables (Low Inflammatory Foods Everyday, LIFE) may have Helps relieve symptoms of chronic migraine .
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Neurology: Mechanisms of beta-amyloidosis implicated in Alzheimer's disease, dementia with Lewy bodies, coexisting localized beta-amyloid and cortical atrophy interactions
Time of Update: 2022-02-20
Since cortical atrophy can reflect the pathological spreading pattern of AD and LBD, a comparative assessment of the cortical thinning pattern associated with cholinergic atrophy and beta-amyloid burden is helpful in understanding these two most common neurodegenerative diseases .
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HUMAN BRAIN MAPPING: Amygdala neurite density imaging reveals interindividual differences in neuroticism
Time of Update: 2022-02-20
It may also lead to innocuous sensory information being falsely perceived as threatening, and lead to altered amygdala responses, reduced neurite density and associated changes in La dendrite structure that may impair its filtering function .
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JAHA: Carotid atherosclerosis predicts blood pressure control in hypertensive patients
Time of Update: 2022-02-20
The presence of CP in hypertensive patients receiving antihypertensive therapy was associated with poor BP control during follow-up, but not with poorer metabolic profile and left ventricular hypertrophy .
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Alz Res Therapy: Alzheimer's treatment, artificial intelligence helps "old medicine new use"
Time of Update: 2022-02-20
Blood vesselIn this study, they propose a web-based artificial intelligence (AI) framework capable of integrating multi-omics data as well as human protein-protein interactome networks to accurately infer drug targets affected by variants identified by GWAS point to identify new treatments .
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Alz Res Therapy: Gender and apolipoproteins that influence fatty acid metabolism
Time of Update: 2022-02-20
The significance of this study lies in the discovery that during aging and cognitive decline, the regulation of fatty acids and related metabolic pathways depends on a complex interrelationship between apolipoprotein-ε4 genotype and sex .
