-
[Science] The truth about the source of SARS-CoV-2 is revealed?
Time of Update: 2021-10-23
Among the bat coronaviruses isolated by scientists in Laos, none of the spike proteins contained a furin cleavage site, a symbolic component of the pandemic virus .
Wang Linfa, a bat coronavirus researcher at Duke National College of Medicine in Singapore, said: “The core function of SARS-CoV-2 is partly of natural origin .
-
[Nature Sub-Journal] War of the Gut: Demystifying how the human gut microbiota resists cholera bacteria
Time of Update: 2021-10-22
Author: Daisy Guide: Recently, researchers published a study in Nature Communications that revealed the way in which Vibrio cholerae interacts with bacteria in the human microbiota .
-
The Liu Hongwei team of the Institute of Microbiology clarified the anti-Alzheimer's Hericium erinaceus diterpene biosynthesis network, and constructed "non-natural" active diterpene engineering bacteria
Time of Update: 2021-10-22
The research team of Hongwei Liu from the Institute of Microbiology, Chinese Academy of Sciences has long been committed to the discovery, active mechanism and biosynthesis of the active ornithane diterpene.
The new structural substances also exhibit neurotrophic activity on PC12 cells.
-
ViMIC-virus mutation, integration and cis-effect database
Time of Update: 2021-10-22
The database interface is simple and friendly, allowing users to quickly query virus mutations, VIS-Cistrome interactions, virus sequences, VIS-VM correlations in viral infectious diseases, and immune cell infiltration levels, and those affected by integration events or viral genes/regions/proteins.
-
ISME J Rhizobia research team from the School of Biology, China Agricultural University reveals the regulatory mechanism of exogenous gene silencers on the adaptive evolution of rhizobia
Time of Update: 2021-10-22
On September 28, 2021, the first-class microbiology journal The ISME Journal published online a research paper by the Rhizobium research team of China Agricultural University: The zinc-finger bearing
-
Annu. Rev. Virol Cheng Gong team of Tsinghua University published an arbovirus review paper (worthy of collection)
Time of Update: 2021-10-22
The review paper systematically summarized the insect vector The multiple mechanisms of animal and plant viruses interacting with the arboreal (mediator) intestines, and the prospects for the infection and transmission mechanism of arboreal and plant viruses in nature are put forward .
-
Biotechnology Advances Central South University of Forestry and Technology and Jiangnan University jointly published a review paper on metabolic energy balance and microbial manufacturing
Time of Update: 2021-10-22
Therefore, how to effectively maintain the balance of metabolic energy during the microbial manufacturing process to improve the efficiency of product synthesis is an important scientific and technical issue .
The relevant strategies proposed have important reference value in the field of engineering cell metabolic energy balance to improve the efficiency of microbial manufacturing .
-
"Nature": Intestinal bacteria is actually a drug "thief"!
Time of Update: 2021-10-22
Figure 2 Differential metabolic interaction of bacterial metabolic enzymes (d, e) and metabolism (f, g) that bind or react with duloxetine is the basis for shaping the structure of the intestinal flora, so the metabolic changes related to drug "storage" Will it also affect the structure of the intestinal flora?
-
Nanjing Agricultural University has made important progress in the construction of microbial fertilizer synthesizing flora
Time of Update: 2021-10-22
Recently, the latest research results of Professor Zhang Ruifu’s research group from the Soil Microbiology and Organic Fertilizer Team of the School of Resources and Environmental Sciences of Nanjing Agricultural University found that the application of typical rhizosphere probiotic Bacillus SQR9 can not only promote plant growth alone, but its metabolites can also induce indigenous “helper” microorganisms.
-
PNAS Northwest A&F University's Shen Xihui team reveals the important role of manganese ions in anti-bacterial natural immunity
Time of Update: 2021-10-21
On October 9, 2021, the Jiang Zhengfan Laboratory of the Beijing University of Science and Technology, the Shen Xihui Laboratory of Northwest A&F University and the Zhou Dongsheng Laboratory of the Military Medical College jointly published an online publication titled T6SS in the Proceedings of the National Academy of Sciences (PNAS) The research paper translocates a micropeptide to suppress STING-mediated innate immunity by sequestering manganese has achieved a new breakthrough in the field of anti-bacterial innate immunity .
-
Cell cover article: Wang Ertao's research group has made significant progress in the study of arbuscular mycorrhizal symbiosis "self-regulation"
Time of Update: 2021-10-21
Research progress On October 12, 2021, the research team of Wang Ertao, Center of Molecular Plant Excellence, published a titled "A phosphate starvation response-centered network regulates mycorrhizal symbiosis" in the top international academic journal "Cell".
-
Du Wenbin's team at the Institute of Microbiology has made new progress in microfluidic high-throughput screening of plastic depolymerases
Time of Update: 2021-10-20
Du Wenbin's research group from the Institute of Microbiology, Chinese Academy of Sciences has long been committed to promoting the industrial application of microfluidic innovation technology, and applied microfluidic technology to the acquisition of environmental non-cultivable and extreme microbial resources, the screening of potential enzyme-producing and active metabolite-producing functional strains And evaluation, the ecological function and evolution of complex microbial communities, and the detection and clinical diagnosis of pathogenic microorganisms.
-
Supplementing probiotics reduces asthma symptoms by regulating the gut microbiome and serum metabolome
Time of Update: 2021-10-19
In summary, Probio-M8 improves the bioactive metabolic potential of intestinal microbes and serum metabolites by regulating the intestinal flora, promotes the secretion and synthesis of some key biologically active compounds in the intestine and blood, and directly regulates the intestine through the systemic circulation system- Lung axis, thereby effectively alleviating small airway inflammation and improving the clinical symptoms of asthma patients .
-
Ketuo Bio Cup Probiotic Knowledge Contest Final
Time of Update: 2021-10-19
The final of the Ketuo Bio Cup Probiotic Knowledge Contest is live, welcome to scan and watch Disclaimer: This article only represents the author's personal views and has nothing to do with China Probiotics.
-
How does the immune system maintain the balance of intestinal flora
Time of Update: 2021-10-19
Tim Rollenske and Professor Andrew Macpherson of the Department of Biomedical Research (DBMR) of the University of Berne was recently able to prove in a mouse model that IgA antibodies can specifically limit benignity at the Hospital of Internal Surgery and Medicine of the University of Bern.
-
Does the gut flora play a role in autoimmune diseases?
Time of Update: 2021-10-19
Since a large part of our immune system is in the intestine, the imbalance of intestinal flora also plays an important role in the occurrence of autoimmune diseases.
-
The Gao Fu team of the Chinese Academy of Sciences Institute of Microbiology has made important progress in the research of GITR/GITRL recognition mechanism
Time of Update: 2021-10-11
Active immune checkpoint molecules such as 4-1BB and GITR are members of the TNF receptor (TNFR) superfamily that have attracted much attention in recent years.
In recent years, the team has carried out a series of research work on the ligand recognition mechanism of immune checkpoint receptor molecules and the mechanism of antibody drug action.
-
The new progress of Xiang Hua/Li Ming's team reveals the mystery of the origin of CRISPR-Cas "guard RNA"
Time of Update: 2021-10-10
Recently, the Xiang Hua/Li Ming team reported their latest research progress in the internationally renowned academic journal Nucleic Acids Research, revealing the evolutionary origin of the CreTA system-derived from the highly degraded and alienated mini-CRISPR structure .
-
Interspecies competition affects microbial extracellular electron transport research progresses
Time of Update: 2021-10-10
These metabolic interactions will affect the extracellular electron transfer process of microorganisms, which in turn affects the efficiency of BESs in degrading pollutants .
In the past, related research mainly focused on metabolic cooperation, but the influence mechanism of interspecies competition on the process of microbial extracellular electron transfer has not been studied yet .
-
A comparative study of deep-sea and shallow-sea soft armoured animal virus groups
Time of Update: 2021-10-10
On the whole, the research team analyzed the deep and shallow sea invertebrate RNA virus groups and delineated the virus ecosystem to provide information on the evolution and spread of marine RNA viruses.
