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Which blood type lives the longest?
Time of Update: 2021-01-15
The study, after adjusting age, sex, education level, smoking, alcohol consumption, physical activity and body mass index, showed a significant correlation between type A blood and gastric cancer risk and mortality compared to type O blood, and non-O type blood was associated with an increased risk of pancreatic cancer.
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JAMA neurology: The efficacy of nilotini in patients with late-middle-aged Parkinson's
Time of Update: 2021-01-15
, a multi-center RCT study was conducted by Northwestern University and the NILO-PD International Research Group to assess nilotinib's safety and tolerance among participants.
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Blood: TLR9, a new potential therapeutic target for chronic lymphocytic leukemia!
Time of Update: 2021-01-15
addition, elevated levels of free DNA were associated with a reduction in the time from the first treatment (TTFT: p=0.003, HR=4.0).
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Blood: Fc-RIIA expression aggravates lupus nephritis and promotes plate plateboard resuscing
Time of Update: 2021-01-15
although chronic plateplate activity and thrombosis are recognized as human SLE characteristics, the exact mechanism of plate plateboard biosis in SLE is still unclear.
in a newly established mouse model based on plate activation of IC-Fc-RIIA mediated human SLE, bone marrow cell expression Fc-RIIA significantly aggravated lupus nephritis and accelerated mouse death.
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NEJM: Large-scale studies have confirmed that high hemoglobin transfusions have no further benefits for premature children
Time of Update: 2021-01-15
This is by far the largest study to compare blood transfusion thresholds for premature infants, and this large, multicenter randomized clinical trial showed that the application of high hemoglobin thresholds to red blood cell transfusions for very low birth weight infants did not improve survival without neurodevelopmental disorders in premature infants between 22 and 26 months of age.
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Blood: Chromosome 20 loss is a feature of degenerative large cell lymphoma associated with breast implants!
Time of Update: 2021-01-15
in this study, Tjitske and others conducted a comprehensive genetic analysis of a relatively large BIA-ALCL queue (n-29) to identify the genome-wide chromosomal copy number variation (CNA) and mutation map of one subset (n-7).
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Blood: Self-transplant or allogeneic transplantation, who should patients with external T-NHL choose?
Time of Update: 2021-01-15
cumulative (non-) relapse mortality, the survival prognosis after standard chemotherapy in young patients with T-cell lymphoma was consolidated by an autobiographic stem cell transplant or an allogeneic stem cell transplant.
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EUR HEART J-CARD PHA: Results of antiplater board therapy in patients with smoking and acute coronary artery syndrome
Time of Update: 2021-01-15
Previous studies have revealed differences in antiplatet drug reactions and clinical outcomes between smokers and nonsmoleors, so the safety and effectiveness of any dual antiplate plateboard therapy (DAPT) downgrade strategy may be related to smoking status.
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In 2021, the National Health and Health Commission will not accept the application for approval of the setting up of the cord blood bank
Time of Update: 2021-01-15
Recently, the General Office of the State Health and Health Commission issued a "notice on the approval of the cord hematopoietic stem cell bank", in order to further improve the umbilical cord blood
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Choose the bottom of the spicy pot or the bottom of the tomato pot?
Time of Update: 2021-01-15
A recent study published in the journal Nature showed that spicy foods activate damage to the receptor nerves, which in turn promotes blood stem cell mobilization in the bone marrow, replenishes blood cells and maintains normal physiological function, a finding that has a positive effect on stem cell transplantation.
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Sci Adv: First Discovery . . People who drink and blush are more likely to develop anaemia/mental retardation/dwarfism
Time of Update: 2021-01-14
known to have the Rs671 mutation, drinking alcohol causes an "alcohol redness reaction." detoxify endogenous aldehyde, the main source of DNA damage repaired by fanconi's anemia pathway.
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J Clin Oncol: Intensive conditioning solutions do not improve the prognostic prognostics of allo-HSCT in older patients with high-risk AML/MDS
Time of Update: 2021-01-14
overall, the enhanced RIC conditioning program, FLAMSA-Bu, does not improve the prognostication of high-risk AML or MDS elderly patients receiving transplant treatment, regardless of THED status prior to transplantation.
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Blood: Short telomere length predicts non-recurrence mortality after stem cell transplantation in MDS patients
Time of Update: 2021-01-14
analysis of the correlation between telomere length and age, somatic cell mutations found that shorter telomere lengths were significantly associated with older, male, somatic cell mutations that affect DNA damage response, and more severe cell reduction before transplantation, but were not related to marrow maternal cell count, MDS therapy history, or past cancer treatment history.
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LETS 2020- Jiang Junhao: Is the current method of vascular preparation evaluation criteria reasonable?
Time of Update: 2021-01-14
the IGNITE study triggered by the thinking on adequate vascular preparation1, IGNITE research results IGNITE research for multi-center, forward-looking research, a total of 296 patients, POBA≤ treatment; Approximately 45% of patients with mezzanine type ≤B and pressure gradient ≤20 mm Hg) (Success BA group) did not have the ideal tube cavity (the exact opposite of the standard) (Failure BA group).
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Blood: Gitto monoantigen can effectively reduce the risk of recurrence in patients with NPM1 mutant AML (AMLSG09-09 trial)
Time of Update: 2021-01-14
in terms of treatment effectiveness, the mesothertic transcription level of NPM1mut in the GO group decreased significantly across all treatment cycles, resulting in a significant increase in the proportion of MRD-negative patients at EOT (56% vs 41% ;P-0.01).
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Blood: Prognosis and associated risk factors for patients with multiple myeloma infected with neo-coronary pneumonia
Time of Update: 2021-01-14
multivariable analysis found that only age, high-risk MM, kidney disease and MM control are still independent predictors of poor prognosms of neo-coronary pneumonia infection.
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Hypertention: Poor blood pressure between arms may be associated with an increased risk of death
Time of Update: 2021-01-14
analysis and evaluation of the data, the results showed that the systolic pressure difference between the upper arms was closely related to all-cause death and cardiovascular time death.
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Blood: The CBL mutation drives the PI3K/AKT signal by enhancing the interaction between LYN and PIX3R1
Time of Update: 2021-01-12
, such as Belizaire, combine functional detection and overall mass spectrometry to define phosphate proteomics, CBL interaction groups, and signal activation mechanisms in a cell line that expresses all-like gene mutations.
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Br J Haematol: The tumor disappeared after a patient with advanced Hodgkin's lymphoma contracted the new coronavirus
Time of Update: 2021-01-12
A 61-year-old patient with severe kidney disease and advanced Hodgkin's lymphoma disappeared four months after contracting the new coronavirus.
In fact, there have been previous reports that the patient also has a history of non-Hodgkin's lymphoma and that the patient's serum response has been negative since infection with SARS-CoV-2, i.e. the inability to produce antibodies.
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Clin Nutrition: The bioavailableness of 25 (OH)D was associated with clinical outcomes in patients with diffuse large B-cell lymphoma
Time of Update: 2021-01-12
study, the researchers aimed to determine the role of total circulatory 25 (OH) D and bio-utilization 25 (OH)D levels in DLBCL patients in determining disease prognostication.
same time, higher plasma total 25 (OH)D levels in DLBCL patients were significantly associated with better disease progression-free survival (PFS) and not with overall survival rate (OS).
