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EMBO Rep: Can tea also fight AIDS? Fudan University has found that green tea extract inhibits HIV replication.
Time of Update: 2020-10-03
more importantly, the team also found that green tea extract EGCG can induce the activation of PEBP1, which in turn induces HIV to continue to lurk by inhibiting HIV transcription and inactivated MAPK/NF-B signaling path.
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Lancet oncol: AML is transplanted with Solafini to maintain the efficacy and tolerance of the treatment.
Time of Update: 2020-10-02
Retrospective studies have shown that Solafinib maintenance therapy may reduce recurrence after transplantation of heterogenetic hematopoietic stem cells in patients with acute myeloid leukemia with FLT3-ITD.
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Clin cancer research: EPZ-6438 combined with R-CHOP to treat diffuse large B-cell lymphoma.
Time of Update: 2020-10-02
method: This is a Phase I clinical trial that evaluates the safety of EPZ-6438 combined R-CHOP for newly diagnosed diffuse large B-cell lymphoma in 60-80 years of age, and identifies the recommended dose (RP2D) for the Phase II trial of EPZ-6438.
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Blood: CBRN mutation associated with multiple myeloma to obtain resistance to amines or pomadamine.
Time of Update: 2020-10-02
Using genome-wide sequencing data from 455 patients and RNA sequencing data from 655 patients, found that three CRBN variants (i.e., point mutations, copy number loss/structural variation, and special transcription variants (such as exon 10 shear variants) gradually increased in frequency, accompanied by IMiD sexual exposure until about one-third of patients with POM incurability developed.
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Blood: Who is the carrier of the mutation driven by Langehans cell tissue cell growth?
Time of Update: 2020-10-02
In-body, CD34-c-Kit-FLT3-plus ancestral cells from exosome blood sources in high- and low-risk LCH patients can produce DC and LC-like cells, but their drive mutations are not easily detected, possibly due to a low percentage of mutated ancestral cells.
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Flow: Deep vein thrombosis in patients with neo-coronary pneumonia.
Time of Update: 2020-10-02
The purpose of this study was to investigate the occurrence of deep vein thrombosis (DVT) in hospitalized patients with new coronary pneumonia, including its rate, risk factors, prognosis, and potential thrombosis prevention strategies.
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Acta Neuropathologica: The reason why MS has less protrusion glial cell differentiation block: exogente immunocytokines, not endogenesis less dexterity glial cytokines.
Time of Update: 2020-10-02
In order to determine whether the internal less protrusion glial cytokines lead to the re-formation of damaged myelin in relapsed-remission-relieving multiple sclerosis (RRMS), we compared adhesive stem cell-sourced less dextinent glial cells (hiOL) from RRMS patients and control groups, where two single-egg twins were inconsistent with multiple sclerosis.
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Lancet Infect Dis: Cabotegravir's PrEP solution reduces HIV incidence by 66%
Time of Update: 2020-10-02
ViiV Healthcare recently reported the final data analysis of the IIb/III HPTN 083 study, which showed a 66% reduction in HIV incidence compared to Gilead Sciences' Truvada (Entouritham/Tinofovir) program, which includes a research-based long-acting cabottegravir pre-exposure prevention (PrEP).
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Blood: Think about it, 15% of HIV-positive people donate blood knowing they are infected with HIV!
Time of Update: 2020-10-02
: First, the use of liquid chromatography - series mass spectrometrometrometrography blind method to detect HIV-positive donors and infections - non-responsive blood donors blood samples, to assess the application of ART.
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Blood: The efficacy of the BTK inhibitor Zebutinib in treating Pyroglobubinemia.
Time of Update: 2020-10-02
(the blood is sticky and difficult to reflow, the fingers become white and cannot be restored for a long time) Bruton tyrosine kinase (BTK) inhibitors exhibit therapeutic activity in Fahrenheit globulinemia.
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Blood: CAR modified memory-like NK cells significantly improved the prognosis of NK immune lymphoma.
Time of Update: 2020-10-02
, the CAR project of ML NK cells enhances the response to drug-resistant cancers and deserves further study, and has the potential to expand the identification of ML NK cells for various NK cell drug-resistant tumors.
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A selection of Blod research on September 17, 2020.
Time of Update: 2020-10-02
. Effects of arginine therapy on mitochondrial function during vascular ocular aches and pain in children with sickle cell disease https://doi.org/10.1182/blood.2019003672 sickle cell disease (SCD) have changed, in part due to low biodetilization of nitric oxide (NO).
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Medicine: Tosili pearl monoantigen is used in the study of the efficacy and safety of familial Mediterranean fever, which is ineffective or insulated with autumn daffodils.
Time of Update: 2020-10-02
, the study is expected to obtain evidence of the long-term safety of TCZ as a potential new treatment for patients with FMF who are resistant to alkaloids or alkaloids.
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Hypertension Annual Meeting 2020 . Zhang Huimin: Secondary hypertension - a major arteritis that cannot be ignored.
Time of Update: 2020-10-02
High blood pressure, which cannot be ignored in patients with aorticitis clinical manifestations, is found in the data of 566 cases of aorticitis in hospitals outside the hospital, and atheritis combined hypertension accounts for the majority (330/566 cases, 58.3%), followed by dizziness caused by progressive cervical arteries, with acute patients suffering from early symptoms of only 10%, indicating that most patients are in other hospitals after missed diagnosis and misdiagnosis.
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CELL: TBL1XR1 mutation drives the occurrence of extraterrid lymphoma.
Time of Update: 2020-10-02
recently, researchers have shown that the TBL1XR1 mutation biases the body's fluid immune response toward abnormally immature memory B cells (MB) while damaging plasma cell differentiation.
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Blood:JAK-STAT pathrapy regulates myeloma CD38 expression and can be used as a therapeutic target.
Time of Update: 2020-10-02
to assess the potential clinical relevance, the researchers further studied the pharmacological inhibition of the JAK-STAT path path to BMSC-sup-induced CD38 reduction.
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Br J Cancer: Long-term exposure to PM2.5 contamination increases the risk of leukemia in older adults.
Time of Update: 2020-10-02
, the study showed that elevated average concentrations of PM2.5 in the residential environment in the year, 5 years and 10 years before diagnosis were associated with a higher risk of leukemia in older adults.
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Cell Research: The latest research advances in SARS-CoV-2 serology between Zhong Nanshan and other teams and hospital patients in China.
Time of Update: 2020-10-02
researchers analyzed the SARS-CoV-2 IgM/IgG antibody sero-positive rate of patients at Guangzhou Medical University First Affiliated Hospital in Guangzhou, the largest city in southern China, and Hubei Cancer Hospital in Wuhan, the center of the outbreak.
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Blood: Inhibiting the D factor blocks complement activation caused by the new coronavirus ratchet protein!
Time of Update: 2020-09-24
However, the nuclear shell (N) protein of SARS-CoV-2 could not be deposited in C3 fragments and C5b-9 on TF1PIGAnull target cells, and the amount of complement factor Bb in the upper fluid of the echithoprotein-treated cells increased.
C5 inhibition prevents the accumulation of C5b-9, but does not block upstream complement activation caused by SARS-CoV-2 echithrin.
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Blood: Immune escape from PD-1 is a defining feature of large B-cell lymphoma rich in T-cells/tissue cells.
Time of Update: 2020-09-23
, the unbiased aggregation of spatially differentiated immune characteristics distinguishes TCRLBCL from the associated B-cell lymphoma subtypes, including classic Hodgkin's lymphoma and DLBCL-NOS.
