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Leukemia is a type of bone marrow cancer that occurs in Denmark at an annual rate of 10.7 per 100,000 people and 7.2 in women between 2012 and 2016.
has been stable for the past 10 years.
can be divided into acute or chronic, mainly lymphatic and bone marrow subtypes (lymphocytes: overproduction of lymphocytes, bone marrow cells: granulocyte overproduction).
Little is known about the risk factors associated with adult leukemia, and although some studies have confirmed a higher risk of leukemia in the family history of hemahitic cancer, little is known about the lifestyle, environment and demographic factors associated with the disease.
currently few population-based epidemiological studies to analyze the relationship between air pollution and leukemia.
The study aims to analyze the relationship between PM2.5 (fine particulate matter), BC (carbon black), NO2 (nitrogen dioxide) and O3 (ozone) average indicators in 1, 5 to 10 years and adult leukemia by analysing data from the Danish National Cancer Registry and air pollution indicators in the Danish DEHM-UBM-AirGIS system model.
researchers obtained a total of 14,986 adult cases diagnosed between 1989 and 2014 and 51,624 matching in age, sex and time.
the effects of exposure to various pollutants on leukemia using independent conditional logic regression models based on socio-demographics.
results showed that the higher the one-year, five-year and 10-year averages of PM2.5 in the environment in which patients were diagnosed, the higher the risk of leukemia, and the results were positively associated with the one-year BC average.
the above results were based on an analysis of participants aged 70 and over.
the correlation was not found for the younger participants.
also found that an increase in the average annual PM2.5 concentration was associated with a high risk of acute myeloid and chronic lymphatic leukemia.
, the study showed that elevated average concentrations of PM2.5 in the residential environment in the year, 5 years and 10 years before diagnosis were associated with a higher risk of leukemia in older adults.
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