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BACKGROUND: Antiretroviral therapy (ART), used for treatment and pre-exposure prevention (PrEP, i.e. preventive measures taken before infection, such as condom use during sexual activity) to prevent HIV infection, is an effective way to end the HIV epidemic.
, the use of ART may affect the risk of HIV transmission.
objective: to conduct three different ART/PrEP prevalence analyses among blood donors.
: First, the use of liquid chromatography - series mass spectrometrometrometrography blind method to detect HIV-positive donors and infections - non-responsive blood donors blood samples, to assess the application of ART.
second, emtricitabine and tenofovir were tested in blood samples from six locations in the United States - unresponsive, 18-45 years old, male, first-time blood donors.
, pre-donation self-reported PrEP use was evaluated for men who participated in the 2017 CDC National HIV BehaviorAl Monitoring (NHBS) in five U.S. cities and had sex with men (MSM).
results: ART was not detected in 300 infection-non-reactive blood donation samples in blind tests, but art treatment was confirmed in 46 of the 299 blood donation samples with HIV-confirmed infection (15.4%, 95% CI 11.5-20.0%).
9 of the 1,494 male samples of first-time donors (0.6%, 95% CI 0.03 - 1.1%) had taken entourourabin and tynofove.
in the NHBS MSM survey, 27 of the 591 respondents (4.8 percent, 95 percent CI 3.2 - 6.9 percent) reported blood donation in 2016 or 2017 and used EPPr during blood donation.
: HIV-positive people who receive ART treatment and those who receive PrEP to prevent HIV infection are donating blood! If blood screening tests fail to detect HIV in the blood of an infected donor, it may increase the risk of HIV transmission.
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