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Progress in the study of atypical keracycline structure diversity
Time of Update: 2021-09-03
Relevant results have recently been published in " The Journal of Organic Chemistry " and " Journal of Nature Products ", among which were published in the "Inactivation of flavoenzyme-encoding gene flsO1 in fluostatin biosynthesis" The paper "leads to diversified angucyclinone derivatives" was selected as the cover article of the current issue ( August 20 ) .
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Comprehensive approach adopted by biologists at the National University of Singapore improves the accuracy of mosquito vector surveillance
Time of Update: 2021-09-03
To solve this problem, the researchers adopted an integrated approach, including a two-pronged strategy to improve sampling accuracy by including mosquito larvae, and the use of short DNA sequences generated by the next generation sequencing (NGS) high-tech platform (Called mini barcodes) for species identification .
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Nature Sub-Journal: Gene patterns provide clues to the evolution of homosexuality
Time of Update: 2021-09-03
There is no "homosexual gene": a lot of research is based on the genetic basis of human sexual behaviorBrendan Zietsch, an evolutionary geneticist at the University of Queensland in Brisbane, Australia, and his colleagues used data from the British Biobank, the National Longitudinal Study of Youth to Adult Health in the United States, and 23andMe in Sunnyvale, California.
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How is the brain formed?
Time of Update: 2021-09-03
Upcoming research at Binghamton University and Harvard Medical School will use computer modeling and advanced imaging of fetal brain development to try to answer some long-standing questions .
Razavi said: "Professor Gholipour and his team have the most accurate MRI and DTI of the fetal brain .
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Researcher Ma Renmin's research group from the School of Physics realizes a magic angle laser based on the localization mechanism of the mode coupling optical field
Time of Update: 2021-09-03
9" >Peking University's School of Physics, State Key Laboratory of Artificial Microstructures and Mesoscopic Physics, and Researcher Ma Renmin's research group at the Center for Frontier Science of Nano Optoelectronics realized a magic angle laser based on the localization mechanism of mode coupling optical fields in a defect-free periodic structure .
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NEB launches new kits to help the analysis of immune repertoires
Time of Update: 2021-09-03
Louis used the NEBNext immunosequencing kit to answer questions about the immune response triggered by the mRNA vaccine .
We found that the SARS-CoV-2 mRNA vaccine can trigger a durable humoral B cell response .
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Guangzhou Health Institute confirms that the modified BCG vaccine can assist in the treatment of drug-resistant tuberculosis
Time of Update: 2021-09-03
Zhang Tianyu's research group at the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences has developed a therapeutic live vaccine, which has been proved by animal experiments to assist in the treatment of drug-resistant tuberculosis .
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Cell answers old questions and draws rhino genealogy
Time of Update: 2021-09-03
"However, we also found that compared with our historical and prehistoric rhino genomes, rhinos now have lower genetic diversity and higher levels of inbreeding," he said .
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A series of outstanding achievements have been made in the construction of the molecular imaging clinical translation platform of Peking University Cancer Hospital
Time of Update: 2021-09-03
Related outcomes to "First-in-human evaluation of a PD-L1-binding peptide radiotracer in non-small cell lung cancer patients with PET" in the title, in August 2021, published in Nuclear Medicine Journal of the magazine .
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Cell Sub-Journal: Deciphering the "Obesity Paradox"
Time of Update: 2021-09-03
The data of this new study was recently published in the journal Cell Metabolism under the title of " Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes .
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Chinese scholars have made progress in the research of organic catalytic asymmetric double halogenation
Time of Update: 2021-09-03
Funded by the National Natural Science Foundation of China (project number: 21825105), Professor Tan Bin's team from Southern University of Science and Technology has made important progress in the field of asymmetric dihalogenation of alkenes and alkynes in organocatalysis .
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Use stem cells to replicate the human brain to produce "brain waves"!
Time of Update: 2021-09-03
▲The brain organoids under the microscope show layered tissue structures and different types of cells (picture source: reference [2]; Credit: UCLA Broad Stem Cell Research Center/Nature Neuroscience)Moreover, when healthy human brain cells respond to stimulation, they will not only send out electric signals, but also produce neural oscillations, that is, brain waves formed by the simultaneous firing of neuron groups .
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Scientists reveal for the first time the neuroimmune process of visceral fat "burning fat"
Time of Update: 2021-09-03
After confirming this fat-burning mechanism of visceral fat, the research team continued to trace the source to find where the signals from the sympathetic nerve endings came from .
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Reduce the risk of patient death by 49%, TCR therapy receives FDA priority review qualification
Time of Update: 2021-09-03
(The original text has been deleted)Reference materials:[1] Immunocore Announces that US Food and Drug Administration and European Medicines Agency accept Biologics License Application and Marketing Authorization Application for Tebentafusp in Metastatic Uveal Melanoma.
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The source of the virus can only be traced to scientists
Time of Update: 2021-09-03
The time limit given by the President of the United States is approaching, and the traceability investigation report of the new crown virus by the US intelligence agency will soon come out .
The history of the world's great plague tells us that scientists are also struggling to trace the source of the virus.
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Nature Sub-Journal: Scientists develop brain organs with complex neural activity
Time of Update: 2021-09-03
Then, while studying organs cultured from stem cells of patients with neurological disorders with Rett syndrome, scientists were able to observe patterns of electrical activity similar to epilepsy, which is a feature of the disease .
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Ouyangbo group reveals a new mechanism for metformin to regulate PD-L1 degradation
Time of Update: 2021-09-03
TRS_Editor A{font-family:;font-size:12pt;}</> On August 24, the international academic journal Nature Communications published online the research results of Ouyang Bo’s research group at the Center for Excellence in Molecular Cell Science (Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences “PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain" .
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Breaking through the limitations, Zhejiang University researchers develop single-molecule electrochemiluminescence microscopy imaging methods
Time of Update: 2021-09-03
Inspired by fluorescence super-resolution microscopy (Nobel Prize in Chemistry in 2014), the research team used spatially isolated molecular reaction positioning information to perform optical reconstruction imaging, and for the first time achieved electrochemiluminescence imaging that broke the optical diffraction limit .
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"Science" publishes an article to demonstrate the animal origin of the new coronavirus
Time of Update: 2021-09-03
The paper believes that the emergence of the new coronavirus has characteristics consistent with natural spillovers, and the possibility of human manipulation by the Wuhan Institute of Virology is extremely small .
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The Nature Sub-Journal of the Chinese Academy of Medical Sciences publishes a new endogenous immune mechanism against influenza virus
Time of Update: 2021-09-03
On July 20, 2021, Guo Fei and Wang Jianwei’s research team published a paper titled MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes on Nature communications, further explaining MARCH8 as a host restriction factor Inhibit the replication of influenza A virus and its molecular mechanism .
