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Preliminary clinical results of TCR-T cell therapy showing anti-cancer activity in a variety of solid tumors are positive
Time of Update: 2021-09-18
On September 13, 2021, Adaptimmune Therapeutics announced its T cell antigen receptor cell therapy (TCR-T) ADP-A2M4CD8 targeting MAGE-A4, the latest data from the Phase 1 clinical trial SURPASS in a variety of solid tumors .
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New technology makes studying gene function easier, faster and more effective
Time of Update: 2021-09-18
Simple selection and laborious screeningThe idea behind this new technology is to use another gene to mark the gene of interest, rather than a physical feature to make the flies resistant or sensitive to specific drugs .
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Artificial intelligence helps scientists identify drugs for yellow fever at low cost
Time of Update: 2021-09-18
Using machine learning techniques, scientists select the most promising virtual chemical structures from thousands of molecules, then obtain or synthesize them, and then test 5 molecules that are promising future drug competitors in test tubes .
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Beijing Hyundai Gundam Biotech's 22 medical device registration certificates for testing kits have been cancelled
Time of Update: 2021-09-18
On September 14, the State Food and Drug Administration issued an announcement stating that, in accordance with the provisions of the "Measures for the Administration of Medical Device Registration", the medical device registration certificates of the following 22 products of Beijing Hyundai Gaoda Biotechnology Co.
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eLife has discovered another key protein for stem cell division
Time of Update: 2021-09-18
The first author of the IRB Barcelona Microtubule Tissue Laboratory, Ricardo Viais, and his leader Jens Lüders, have determined that the protein complex augmin is a key element of stem cell division during embryonic brain development .
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"Nature" compilation: blue food can improve diet, good for women 3 times more than men
Time of Update: 2021-09-18
The author of the paper also simulated the impact of an increase in global blue food production by about 8% by 2030, and predicts that this may reduce the price of related foods by 26%, which is expected to improve the intake of trace elements for up to 166 million people .
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The father is the director of the factory, and the son receives the Nobel Prize... This discovery has changed the understanding of cells
Time of Update: 2021-09-18
Illustration: Mattias Karlen)After the first generation of iPSC is injected into nude mice, it can develop into various types of cell tissues such as nerve tissue, muscle cells and small intestine cells, but some genes are still epigenetic differently from embryonic stem cells .
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Genome Med. Bai Fan's research group and collaborators revealed the co-evolution characteristics of EB virus-positive gastric cancer tumor cells and EB virus, and discovered potential therapeutic targets
Time of Update: 2021-09-18
On September 8, 2021, Peking University Biomedical Frontier Innovation Center (BIOPIC), Beijing Future Gene Diagnosis Advanced Innovation Center (ICG) Bai Fan's research group and Sun Yat-sen University Cancer Prevention Center Zhong Qian's research group cooperated in Genome Medicine Published a paper titled The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma in the form of a research long article .
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The research team of Wang Zhen and Li Yixue of the Institute of Nutrition and Health jointly published the latest research results of Kawasaki disease single-cell immune atlas
Time of Update: 2021-09-18
In this study, researchers carried out a single-cell transcriptome study of peripheral blood mononuclear cells (PBMC) of Kawasaki disease and normal children before and after immunoglobulin treatment, revealing that peripheral immune cells and their Dynamic changes in subtypes (Figure AC) .
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"Immunity" new findings on B cells may improve vaccine design
Time of Update: 2021-09-18
A new study from Karolinska Institute in Sweden describes how B lymphocytes, the immune cells that make antibodies, choose between different cell fates to balance the acute immune response and memory response to prevent future problems.
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Knife out of the sheath: How does single-cell sequencing technology fight disease?
Time of Update: 2021-09-18
In addition to tumors, single-cell RNA sequencing technology can also detect the mRNA expression profiles of different cells in embryonic development stages, so as to screen out key genes at different organ development stages and provide a reference for stem cell organ transplantation .
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Science Immunology: Memory killer T cells are injected into the spleen during influenza infection
Time of Update: 2021-09-18
"UAB researchers used a mouse/influenza virus infection model and found that the initiation in the spleen is completed by a part of migrating lung dendritic cells, which leave the lymph nodes, enter the bloodstream, and return to the spleen .
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New PNAS research shows that the symptoms of dementia are written in the blood
Time of Update: 2021-09-18
In this study, the research team analyzed blood samples from 8 dementia patients and 8 healthy elderly people .
Researchers have found that these antioxidant compounds from food are abundant in red blood cells in healthy elderly people .
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Diabetes research: a new model for studying beta cell function
Time of Update: 2021-09-18
The beta cells of the pancreas synthesize, store and secrete insulin, which controls the level of glucose in the blood . The dysfunction of these cells is the main cause of adult-type diabetes, a di
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Do you want to lose weight successfully? First ask if your gut microbes are happy!
Time of Update: 2021-09-18
Christian Diener, said: "When our gut bacteria Slowing down one's own growth and breaking down dietary fiber into energy-rich sugars, which enter our blood before being fermented by microorganisms into organic acids, may be particularly difficult to lose weight .
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$26.5 million to discover a new treatment for HIV
Time of Update: 2021-09-18
"The HOPE Collaboration Laboratory is one of 10 teams funded for 5 years under the Martin Delaney Collaboratories program, which is the flagship project of the National Institutes of Health for AIDS treatment research .
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The CD20xCD3 bispecific antibody CM355 jointly developed by Nuocheng Jianhua and Connoa was approved for clinical use
Time of Update: 2021-09-18
Beijing, September 16, 2021/PRNewswire/ - Nuocheng Jianhua (Hong Kong Stock Exchange code: 09969) and Connoa (Hong Kong Stock Exchange code: 02162) jointly announced today that they have received the National Drug Administration The “Notice of Drug Clinical Trial Approval” approved and issued by the Bureau agreed to the CD20xCD3 bispecific antibody CM355 developed by the joint venture company Tennuo Jiancheng to carry out clinical trials of CD20+ B-cell hematoma .
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Advanced Science discovers the key protein of diet-induced thermogenesis and reveals its mechanism of action
Time of Update: 2021-09-18
In September 2021, the Jin Wanzhu research team of the Institute of Zoology, Chinese Academy of Sciences published an article Hepatokine pregnancy zone protein governs the diet-induced thermogenesis through activating brown adipose tissue (DIO: 10.
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Loss of SNORA73 makes cell metabolism reprogrammed and has a protective effect on steatohepatitis
Time of Update: 2021-09-18
Here, the authors demonstrated that the destruction of the H/ACA SNORA73 box small nucleolar RNA encoded in the small nucleolar RNA host gene 3 (Snhg3) resulted in the resistance of cultured cells to lipid-induced cell death and general oxidative stress .
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Yipinhong's wholly-owned subsidiary obtained the registration certificate of bromhexine hydrochloride injection
Time of Update: 2021-09-18
According to the approved drug instructions, the company's bromhexine hydrochloride injection is used for patients with chronic bronchitis and other respiratory diseases such as asthma, bronchiectasis, and silicosis who are difficult to cough up when oral administration is difficult .
