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The latest phase 2 results of NASH's innovative therapies are announced, significantly reducing the level of fibrosis biomarkers
Time of Update: 2021-09-19
On September 13, 2021, Hepion Pharmaceuticals announced the additional efficacy data of the phase 2a clinical trial AMBITION of the new cyclophilins inhibitor CRV431 under investigation .
com/news-release/2021/09/13/2295714/0/en/Additional-Data-from-Hepion-Pharmaceuticals-Phase-2a-AMBITION-Trial-Further-Strengthens-CRV431-Clinical-Profile-and-Paves -Way-for-Initiation-of-Phase-2b-ASCEND-NASH-Clinical-Progra.
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New discovery: COVID-19 infection + 2 doses of vaccine = super immunity, can fight many mutations
Time of Update: 2021-09-19
According to the National Public Radio (NPR) report, the latest research shows that after some people are infected with the new crown virus, after two doses of Pfizer or Moderna vaccine, the body's immune system will produce a large number of antibodies .
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The first Morquio A syndrome rat model, gene therapy shows therapeutic potential
Time of Update: 2021-09-19
Fatima Bosch, a researcher at UAB and the leader of the study, explained: “Gene therapy on four-week-old Morquio A rats completely restored the clinical symptoms of the disease, such as changes in bone growth, tooth deformities and fragility, Articular cartilage pathology, as well as respiratory and cardiovascular complications .
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Artificial intelligence can detect dementia years before symptoms appear
Time of Update: 2021-09-19
Researchers at the University of Cambridge say that artificial intelligence can detect early signs of dementia through a simple brain scan long before the main symptoms appear, and in some cases even before any symptoms appear .
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A general system for decoding any type of data sent over the network
Time of Update: 2021-09-19
Researchers from the Massachusetts Institute of Technology (MIT), Boston University (Boston University) and Ireland’s Maynoth University (maynoth University) have now developed the first chip that can decode any code, regardless of its structure, using a The general decoding algorithm called Guessing Random Additive Noise Decoding (GRAND) has the highest accuracy .
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Nearly a quarter of patients survived for more than 3 years. Long-term clinical results of BMS dual immunotherapy are positive
Time of Update: 2021-09-19
Test data show that its anti-PD-1 inhibitor nivolumab, combined with CTLA-4 inhibitor ipilimumab constitutes dual immunotherapy, compared with platinum-containing standard chemotherapy, the first-line treatment of unresectable malignant interpleural Patients with dermatoma (MPM) can obtain long-lasting survival benefits (regardless of the histological characteristics of the tumor) .
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Yan Xiyun's research group and Zhu Mingzhao's research group collaborated to reveal the molecular mechanism of TCR signal activation
Time of Update: 2021-09-19
On September 7, 2021, the research group of Researcher Mingzhao Zhu from the Institute of Biophysics of the Chinese Academy of Sciences and the research group of Academician Yan Xiyun jointly published a titled "CD146 bound to LCK promotes TCR signaling and anti-tumor immune response in mice" in the Journal of Clinical Investigation .
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A synthetic molecule can improve the response of some cancer patients to immunotherapy
Time of Update: 2021-09-19
Picture: The new compound EnPGC-1, which activates the mitochondria of mouse T cells, can make cancer immunotherapy more effective .
"The team hopes to find a way to increase mitochondria in T cells to improve the response of cancer patients to PD-1 blockade monotherapy .
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New study by Nobel laureate: eating beef may indirectly cause cancer?
Time of Update: 2021-09-19
How to eat beef?Health experts recommend that livestock and poultry meat and fish meat should be controlled at 280 ~ 525 grams per week, and the daily intake of meat products should be 40 ~ 75 grams .
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"Science" The inner workings of the membraneless cell compartment
Time of Update: 2021-09-19
The researchers say that their work can promote scientific understanding of cell evolution and help scientists in the food and chemical industries develop better ways to prevent the separation of liquid mixtures .
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Painless patients double oral multi-mechanism migraine therapy within 2 hours, expected to be approved next year
Time of Update: 2021-09-18
On September 14, 2021, Axsome Therapeutics announced that the US FDA has accepted the New Drug Application (NDA) for the compound migraine therapy AXS-07 with multiple mechanisms of action for the acute treatment of migraine.
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A new study is launched for all patients with colorectal cancer
Time of Update: 2021-09-18
These cancers occur in young healthy people without risk factors," said Dana-Farber, director of the young-onset Colorectal Cancer Center and Colorectal Cancer Project.
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To make the "cold" tumor "hot", a small amount of radiation has a great effect
Time of Update: 2021-09-18
"After studying several drug combinations, they selected four for mouse research: an existing antibody that can stimulate the receptor CD40 on dendritic cells and increase their activity; low-dose chemotherapy; Cyclophosphamide, known to inhibit treg; and a combination of anti-ctla-4 and anti-pd-1 immunotherapy, they can mobilize T cells to attack tumors .
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The brain will also "one area with two purposes". The neurons that control habit also learn new behaviors.
Time of Update: 2021-09-18
The test results showed that after only one training session, neurons in a specific area of the striatum of the experimental group were significantly more active than those in the control group, indicating that they played a role in learning .
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A new approach to the treatment of epileptic seizures in patients with autism
Time of Update: 2021-09-18
Yang Yang, assistant professor of medicinal chemistry and molecular pharmacology at Purdue University in the United States, and his team solved this problem, including the first author of the paper and postdoctoral fellow Zhang Jingliang .
Severe deficiency of the voltage-gated sodium channel NaV1.
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Engineers planted pancreas "organoids" to imitate real pancreas
Time of Update: 2021-09-18
Using a special gel that mimics the extracellular environment around the pancreas, researchers were able to cultivate pancreatic "organoids", allowing them to study important interactions between pancreatic tumors and their environment .
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The latest discovery of Johns Hopkins University: antiparasitic drugs can prevent pancreatic cancer!
Time of Update: 2021-09-18
In a study published in the journal Oncotarget, Gregory Riggins, MD, professor of neurosurgery and oncology at Johns Hopkins University School of Medicine, his team used two different mouse models to determine anti-parasite resistance The drug mebendazole can slow down or prevent the growth and spread of early and late pancreatic cancer .
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Scholars of Jinan University change the fate of cancer: transform glioma cells into neurons
Time of Update: 2021-09-18
Chen Gong, a former professor at Pennsylvania State University and now director of the Brain Repair Center of Jinan University in China, has developed a new type of gene therapy that can reprogram glioma cells into functional neurons for the treatment of glial cells.
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Avoid antibiotics and use "good" bacteria to directly destroy "bad" bacteria
Time of Update: 2021-09-18
In this study at Tel Aviv University, researchers "borrowed" a toxin injection system called type 6 secretion system from a pathogenic bacterium and introduced it into a "friendly" bacterium-Nitrogen Arc 。 In the bacteria .
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Cooperating to cultivate carbon capture sorghum
Time of Update: 2021-09-18
2 million partnership with Nadia Shakur, principal investigator and senior researcher at the Donald Danforth Plant Science Center The scientist and her team are responsible for identifying and developing sorghum plants that can better capture and store atmospheric carbon .
