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If genes related to autism are missing, it will lead to a decrease in myelin
Time of Update: 2021-12-24
A new study found that in mice with missing genes related to autism spectrum disorders, myelin (an insulating sheath that surrounds nerves that allows electrical impulses to effectively propagate through the central nervous system) is reduced .
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2021 International Conference on Cancer and Aging and the Fifth Doctoral Forum
Time of Update: 2021-12-24
Chinese Chairman Liu Jianfeng, Professor of Huazhong University of Science and Technology, French Chairman, Prevost Gregoire, President of CIPREVO, France, and Professor Sylvain Fisson, representative of Évry University in France, then welcomed the experts, scholars and students participating in the conference and kicked off the conference .
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Cell Rep: Functional dependence between key intermediary genes of different tumors
Time of Update: 2021-12-24
In a new study published today in Cell Reports, the research team used a network model to study a series of interactions that are critical to malignant tumors, which may be fertile ground for a wide range of cancer treatments .
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PNAS's newly discovered inflammatory mediator stimulates tissue regeneration and controls granuloma formation
Time of Update: 2021-12-24
The biosynthetic product cysteine isomers discovered by the team can accelerate the tissue regeneration of planarians injured by surgery and inhibit the development of granulomas in human peripheral blood leukocytes .
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Loss of ATF4 leads to functional senescence-like wear and tear of adult hematopoietic stem cells
Time of Update: 2021-12-24
Here, we report that ATF4 deficiency causes severe HSC defects and various aging-like phenotypes through cell-autonomous mechanisms .
Mechanically,ATF4Deficiency can damage HSC function, has an aging-like phenotype, and reduces the occurrence of leukemia by regulating HIF1α and p16Ink4a.
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A biological paradox provides new insights into the mystery of cancer
Time of Update: 2021-12-24
Its purpose is to assess the species-specific cancer mortality of various mammals, re-examine the claims of Pitto's paradox in a rigorous and quantitative manner, and explore possible cancer suppression mechanisms related to humans and animals fighting diseases .
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Moderna released the latest data on mRNA vaccines: the level of neutralizing antibodies in the booster needle increased by 83 times
Time of Update: 2021-12-24
Article source: Medical Rubik's Cube InfoAuthor: Shi BeiOn December 20, Moderna announced the preliminary neutralizing antibody data of the mRNA new crown vaccine (elasomeran, mRNA-1273) at 50 µg and 100 µg doses against the Omicron variant .
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Dymax Demas launches 1040-M steam pressure sterilization adhesive
Time of Update: 2021-12-04
Shenzhen, October 13, 2021/PRNewswire/ - Dymax, a leading manufacturer of fast light-curing materials and equipment, recently launched the new MD® series adhesive 1040-M, which is mainly used in medical device assembly .
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Biologists solve the mystery of Darwin's pigeon and discover the relationship between unexpected discovery and human genetic diseases
Time of Update: 2021-12-04
In a recent research paper published in the academic journal Current Biology, biologists at the University of Utah in the United States have pinpointed a gene that controls short beak ROR2 in the genome of pigeons.
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FDA approves Keytruda combination therapy as first-line treatment of cervical cancer to reduce the risk of death by 36%
Time of Update: 2021-12-04
(MSD) announced that the US FDA approved the PD-1 inhibitor pembrolizumab (pembrolizumab, English trade name Keytruda) in combination with platinum-containing chemotherapy, with or without bevacizumab Monoclonal antibody (bevacizumab) is the first-line treatment for patients with persistent, recurrent or metastatic cervical cancer whose tumors express PD-L1 (CPS score ≥ 1) .
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Alzheimer's disease is expected to achieve early non-invasive screening
Time of Update: 2021-12-04
The Xuanwu Hospital of the Capital Medical University of the National Medical Center for Neurological Diseases and the Peking University School of Psychology and Cognitive Science team jointly revealed the neural mechanism and early diagnosis value of "binaural auditory processing", a key link in auditory perception, in the pathogenesis of Alzheimer's disease , It is expected to achieve early non-invasive screening for Alzheimer's disease .
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Chimeric exosomes bring new ideas for tumor immunotherapy
Time of Update: 2021-12-04
Science and Technology Daily, Beijing, October 21 (Reporter Lu Chengkuan) On the 21st, the reporter learned from the Institute of Process Engineering of the Chinese Academy of Sciences that the researchers of the Institute created a chimeric exosome that achieved dual targeting of lymph nodes and tumor tissues.
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Junshi Biology and the Institute of Microbiology, Chinese Academy of Sciences announce cooperation to develop Zika virus vaccine
Time of Update: 2021-12-04
With the solid basic research capabilities of the Institute of Microbiology, Chinese Academy of Sciences, and Junshi Bio's entire industry With the strength of chain operations, both parties will accelerate the global clinical application of Zika virus vaccines, and use local innovations to contribute to disease prevention and control in China and the world!"[1] Science, 369, 1123–1128 (2020)[2] Dai, L.
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FDA granted fast track qualification for the new immunotherapy nemvaleukin+Keytruda program
Time of Update: 2021-12-04
Alkermes recently announced that the US Food and Drug Administration (FDA) has granted nemvaleukin alfa (nemvaleukin) fast track designation (FTD), combined with Merck’s anti-PD-1 therapy Keytruda (generic name: pembrolizumab, pembrolizumab) Anti), used to treat platinum-resistant ovarian cancer .
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The latest development of ADA-SCID gene therapy in 90% of children with continued health after ten years of treatment
Time of Update: 2021-12-04
A few days ago, researchers at the University of California, Los Angeles reported on "Blood" related data on experimental gene therapy for severe combined immunodeficiency (ADA-SCID) children.
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Can an anti-cancer therapy fix the tumor?
Time of Update: 2021-12-04
Yuri Sykulev, a professor of immunology at Thomas Jefferson University in the United States, found that CAR-T cells often require higher antigen levels in the tumor if they want to work in melanoma .
This suggests that if the target antigen level of solid tumors is very low, CAR-T cells may be difficult to function .
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With "Cloud Pathology", patients may get an authoritative diagnosis within one day
Time of Update: 2021-12-04
"In order to solve these problems, Xiangya Hospital of Central South University took the lead in exploring the'cloud pathology' consultation platform in 2015 to meet the needs of basic hospitals for difficult pathology consultations and rapid intraoperative consultations, and to help improve the medical service capabilities of primary medical institutions .
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Innovative HIV combination therapy reaches two phase 3 clinical trial endpoints to support the submission of regulatory applications
Time of Update: 2021-12-04
Reference materials:[1] Merck Announces Positive Top-Line Results from Pivotal Phase 3 Trials Evaluating Investigational, Once-Daily Oral Fixed Dose Combination of Doravirine/Islatravir for the Treatment of People with HIV-1 Infection.
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Designed to functionally cure hepatitis B antisense oligonucleotide therapy enters the clinic
Time of Update: 2021-12-04
On October 11, 2021, Aligos Therapeutics announced that ALG-020572 has completed the first patient administration in a phase 1 clinical trial .
(The original text has been deleted)Reference materials:[1] Aligos Therapeutics Begins Dosing with Antisense Oligonucleotide Drug Candidate, ALG-020572, in Healthy Volunteers in a Phase 1 Proof-of-Concept Study.
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New crown vaccine blockbuster data released!
Time of Update: 2021-12-04
Characteristics of participants who signed up for clinical trialsResearchers found that before the booster shot, compared with Pfizer or Moderna vaccine, the baseline serum binding antibody of people who received the Johnson & Johnson vaccine was 3 to 15 times lower .
