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Henan Provincial Key Laboratory of Brain-Targeted Bio-Nano Drugs published the latest GBM treatment research progress in ACS Nano and Journal of Controlled Release
Time of Update: 2022-04-19
The results were published in the journal ACS Nano as " Brain-Targeted Codelivery of Bcl-2/Bcl-xl and Mcl-1 Inhibitors by Biomimetic Nanoparticles for Orthotopic Glioblastoma Therapy " .
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Geographical distribution pattern of plants from tropical to subtropical China in Indochina...
Time of Update: 2022-04-19
This study not only provides a scientific example for the formation of the geographical distribution pattern of plants in the tropical and subtropical regions of China from the Indo-China Peninsula, but also provides further clues for revealing the historical construction process of subtropical evergreen broad-leaved forests in China, and draws attention to China The importance of subtropical regions in biodiversity conservation and maintenance mechanisms .
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The team of Professor Fu Xianghui of the State Key Laboratory of Biotherapy published a paper in Nature Communications revealing the effect of RNA-G quadruplex on new coronavirus infection...
Time of Update: 2022-04-19
In this context, this study is the first in the world to explore the existence and regulatory role of RG4 in the SARS-CoV-2 virus genome and key factors of host cell virus infection, and its targeted intervention effect on new crown infection .
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Chinese scholars have made new progress in the research of 5G/6G mobile terminal power amplifier chips and base station power amplifier circuits
Time of Update: 2022-04-19
The research results of mobile terminal power amplifier chips are based on ""A parallel-series hybrid 28GHz Doherty power amplifier based on three-port compact transformer realized by 55nm CMOS process, the fallback efficiency at 6-/12-dB output power is 20.
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New PET imaging technique improves prostate cancer treatment
Time of Update: 2022-04-19
Positron emission tomography (PET) imaging is central to the treatment of prostate cancer, although the production of radiotracers for PET imaging is often complex and time-consuming, limiting availability to patients .
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Prof. Jianbing Yan won the L. Stadler Mid-Career Award
Time of Update: 2022-04-19
. It is understood that the Lewis Stadler Mid-Career Award was established by the Maize Genetics Cooperative to nominate and reward independent scientific research for 9 to 20 years, and contributions to maize (or other related species) genetics research.
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Nature: A new study on how bacteria swim could help prevent the spread of disease
Time of Update: 2022-04-19
Image: A research team led by the University of Minnesota Twin Cities has studied how bacteria swim in complex liquids to gain insights into how microbes move through different environments, such as their natural habitat or inside the human body .
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Chinese scholars have made new progress in the regulation mechanism and intervention of the circadian clock of thrombotic events
Time of Update: 2022-04-19
: 81625002, 81930007, 91839301, 81470389, 81800307), the research team of Professor Bu Jun from Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine has made new progress in the regulation mechanism and intervention of the circadian clock in thromboembolic events , with the title "Circadian nuclear receptor Rev-erbα is expressed by platelets and potentiates platelet activation and thrombus formation", published on March 10, 2022 in Published online in the European Heart Journal .
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Nuclear microRNAs are being developed for cardiovascular disease treatment
Time of Update: 2022-04-19
MicroRNAs are small RNA molecules that regulate gene expression .
The use of small RNAs to increase the expression of VEGFA provides a new option for the treatment of ischemic cardiovascular disease in which the blood supply in tissues is compromised .
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Shanghai Jiaotong University Zhang Yu's team designed new primers to help detect microbial diversity in trenches
Time of Update: 2022-04-19
Recently, Yang Na, a doctoral student under the guidance of researcher Zhang Yu from the School of Oceanography, Shanghai Jiao Tong University, published a paper entitled "Novel primers for 16S rRNA gene-based archaeal and bacterial community analysis in oceanic trench sediments" in the classic journal "Applied Microbiology and Biotechnology" in the field of environmental microbiology.
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Cell: Ancient DNA sheds light on the origins of the Avars
Time of Update: 2022-04-19
was the fastest long-distance migration in human history that we have been able to reconstruct to date," explains Choongwon Jeong, co-senior author of the study .
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How does clearing bad mitochondria affect stem cell division?
Time of Update: 2022-04-19
"I study a process called mitochondrial phagocytosis, which cleans up these damaged mitochondria," said Alicia Pickrell, assistant professor in Virginia Tech's College of Neuroscience.
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Li Long's group from the School of Life Sciences reveals the dynamic changes of the phospholipid transporter flippase in the cell membrane
Time of Update: 2022-04-19
This paper reports the conformational changes of phospholipid transferase (lipid flippase) in different lipid membranes, and discovers the resting state of this protein family for the first time, which provides an important molecular basis for understanding the formation of cell membrane asymmetry .
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Research progress of bio-enhancement mechanism in directional humification of kitchen waste in Chengdu Biological Institute
Time of Update: 2022-04-19
In order to explore the mechanism of bioaugmentation on the formation of humic acid during the composting process of kitchen waste, Zhou Xiaolu, a postgraduate student at the Chengdu Institute of Biology, Chinese Academy of Sciences, under the guidance of researcher Li Dong, used kitchen waste as raw material, and added a biodegradable product in the early stage of composting.
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Xiamen University discovers a pathway that promotes remyelination
Time of Update: 2022-04-18
On April 2, 2022, Zhang Liang's team of our hospital and Wang Zhanxiang's team of the First Affiliated Hospital published a research result entitled Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling in the Journal of Clinical Investigation, which was the first discovery of COPII-mediated The autocrine function of oligodendrocytes plays an important role in oligodendrocyte differentiation and remyelination, providing new ideas for the treatment of demyelination-related diseases .
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Mysterious brain dark matter
Time of Update: 2022-04-18
Now, a team in his department has taken a closer look at this little-explored brain component: In the fruit fly brain, they were able to show that electrical synapses occur in nearly all brain regions and can affect a single Function and stability of nerve cells .
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Learning from single cells: new techniques to unravel gene regulation
Time of Update: 2022-04-18
Analysis of single cells with EpiDamIDTo understand how PTMs affect gene expression, first authors Franka Rang and Kim de Luca devised a new method to pinpoint the location of modifications .
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Xiao Zeyu's research group from the School of Basic Medicine published the research results of polymer Raman probes for high-sensitivity imaging in vivo
Time of Update: 2022-04-18
The probe overcomes the bottleneck that traditional organic polymer materials are difficult to generate high-sensitivity Raman signals due to fluorescence interference, realizes in vivo imaging of micrometastatic tumors in mouse colon cancer models, and achieves a spatial resolution comparable to that of SERS probes ; and achieved non-invasive microvascular imaging (Figure 1) .
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Nature discovers new cell type with regenerative properties in human lungs
Time of Update: 2022-04-18
Figure: Human ES cell-derived RASCs (respiratory airway secretory cells, which are gradually transformed into alveolar type 2 cells during culture) Researchers at the Perelman School of Medicine at the University of Pennsylvania have discovered a new type of cell located deep in the human lung that may play a key role in human lung disease .
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"JAMA" sub-issue: Neuron loss causes sleepiness
Time of Update: 2022-04-18
"We were able to show what our previous research pointed to -- that in Alzheimer's patients who need to nap all the time, the disease damages the neurons that keep them awake," said neuropathologist Grinberg, who worked with psychiatrists Thomas Neylan, MD, is the senior author of the study, which appears in the April 4, 2022, issue of JAMA Neurology .
