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The protective shield of cancer cells must be broken!
Time of Update: 2022-05-21
According to new research in the Proceedings of the National Academy of Sciences (PNAS), for immunotherapy to really work, it is necessary to address the protective environment that cancer cells create for themselves .
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Largest-ever schizophrenia study published reveals genetic links to disease
Time of Update: 2022-05-21
Relevant research results were published online in the journal Nature Genetics on April 8, 2022, with the title "Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia" .
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Biogen's Aduhelm is restricted by medical insurance, and Eisai, Eli Lilly and Roche accelerate the development of Alzheimer's disease treatment
Time of Update: 2022-05-21
Eisai said in a statement that the company expects to complete a rolling submission for lecanemab through the accelerated approval pathway in the coming months, following last week's CMS decision on Aduhelm's restrictive coverage .
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$960M Expanded Drug Delivery Technology Offers New Subcutaneous Option for Biologics
Time of Update: 2022-05-21
Combining the auto-injector platform and Halozyme's ENHANZE technology for subcutaneous biologics has the potential to create an industry-leading drug delivery business, according to the press release .
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Junshi Bio's Toripalimab in the Treatment of Small Cell Lung Cancer Receives FDA Orphan Drug Designation
Time of Update: 2022-05-21
On April 13, Toripalimab, an anti-PD-1 monoclonal antibody independently developed by Junshi Bio for the treatment of small cell lung cancer (SCLC), was granted orphan drug designation by the U.
This is the fifth orphan drug designation for Toripalimab .
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LENZ Therapeutics and Keixing Pharmaceutical reach an exclusive license agreement in Greater China
Time of Update: 2022-05-21
On April 14, LENZ Therapeutics announced that it has signed an exclusive agreement with Keixing Pharma to develop and commercialize LNZ100 (acetylcridine) and LNZ101 (acetylcridine + brimonidine) for the treatment of presbyopia in Greater China.
License Agreement .
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Uranium detected in two-thirds of U.S. community water system monitoring records
Time of Update: 2022-05-21
Anne Nigra, PhD, assistant professor of environmental health sciences at Columbia University's Mailman School of Public Health, said: "Previous research has found an association between long-term uranium exposure and increased risk of high blood pressure, cardiovascular disease, kidney damage and lung cancer with high levels of uranium exposure .
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Tree-ring evidence for extreme climate events in the Himalayan Karnali Basin...
Time of Update: 2022-05-21
This study reconstructs the history of regional hydrological changes in the central and western Himalayas with high precision for the first time, which can provide a reference for the scientific management and utilization of water resources in the basin under the background of current and future climate change .
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mRNA vaccine helps CAR-T therapy in solid tumors with an overall response rate of 43%
Time of Update: 2022-05-21
▲The mechanism of action of BNT211 (Image source: BioNTech official website)Preliminary clinical trial results presented at the AACR annual meeting included 16 patients who received CLDN6-targeted CAR-T therapy at a dose of 1x10^7 and two patients who received CAR-T therapy at a dose of 1x10^8, some of whom also received CARVac treatment .
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The plant diversity research team of the Chengdu Institute of Biology has made progress in the chloroplast comparative genomics and palynology research of the genus Sophora genus of the leguminous family
Time of Update: 2022-05-21
Since 2018 , the plant diversity research team of Chengdu Institute of Biology, Chinese Academy has extensively collected research materials of Sophora genus, and used Illumina sequencing technology and scanning electron microscopy ( SEM ) to study the chloroplast genome characteristics and sporopollen characteristics of Sophora , respectively.
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South China Botanical Garden Research Reveals the Response Mechanism of Phosphorus Cycle to Climate Warming
Time of Update: 2022-05-20
Based on the long-term natural warming platform of Dinghushan Station in the South China Botanical Garden, Liu Juxiu's research team systematically assessed the impact of seven -year warming on phosphorus cycling in tropical forest ecosystems .
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Qin Zhihai's research group revealed that S100A4+ effector memory CD8+ T cells sub...
Time of Update: 2022-05-20
On April 16, 2022, Qin Zhihai's research group from the Institute of Biophysics, Chinese Academy of Sciences published an article online entitled "Dysfunction of S100A4 + effector memory CD8 + T cells aggravates asthma" in the European Journal of Immunology .
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Can air cause cancer?
Time of Update: 2022-05-20
"Although FPM has the potential to cause mutations, recent studies have shown that FPM does not directly promote -- and may even inhibit -- the growth of lung cancer cells, " explains first author Zhenzhen Wang, an associate researcher at Nanjing University (NJU).
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Professor Wang Pengfei's collaborative paper was published in Review of Economic Dynamics
Time of Update: 2022-05-20
9" >A few days ago, the collaborative paper "Asset Bubbles and Foreign Interest Rate Shocks" by Professor Wang Pengfei, Deputy Dean of Peking University Shenzhen Graduate School and Dean of Peking University HSBC Business School, was officially published in the SSCI journal Review of Economic Dynamics (Volume 44, 2022, pp.
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Xu Shuhua's team released the ArchaicSeeker2.0 method to reconstruct the analysis process of the ancient human gene communication model
Time of Update: 2022-05-20
<> </><> </><> </>On April 14 , 2022 , Star Protocols , an academic journal of CellPressThe research results " Detecting archaic introgression and modeling multiple-wave admixture with ArchaicSeeker
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Wei Wensheng's research group from the School of Life Sciences reports on the circular RNA technology platform and the new anti-new coronavirus vaccine developed accordingly
Time of Update: 2022-05-20
9" >On March 31, 2022, Wei Wensheng's group from Peking University School of Life Sciences published a research paper titled " Circular RNA Vaccines against SARS-CoV-2 and Emerging Variants " online in the journal Cell , reporting for the first time a circular RNA vaccine technology platform , and the circular RNA vaccine developed against the new coronavirus and its series of variants .
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Advances in stoichiometric regulation mechanisms of microbial life strategies on priming effects and soil carbon balance
Time of Update: 2022-05-20
Exogenous carbon and nutrient inputs can affect microbial growth and induce soil carbon mineralization-inspired effects, which in turn stimulate the formation and mineralization of soil organic carbo
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Shenzhen University's latest article: DNA methylation changes during tomato phosphorus deficiency
Time of Update: 2022-05-20
Through the functional analysis of the tomato microRNA164 precursor gene SlMIR164A in fruit chloroplast development and fruit ripening, this study revealed the mechanism of microRNA mediated by specific target genes, thereby finely regulating fruit ripening and quality .
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Nat Commun Wang Yiguang's team provides a new strategy for analyzing the intracellular and intracellular distribution of nanomedicine and its contribution to efficacy
Time of Update: 2022-05-20
On April 14, 2022, the internationally renowned journal Nature Communications published online the latest research results of Wang Yiguang's research team from the State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmacy, Peking University, "Dissecting extracellular and intracellular distribution of nanoparticles and their contribution to therapeutic response by "monochromatic ratiometric imaging" ( monochromatic ratiometric imaging technology to analyze the intracellular and extracellular distribution of nanomedicine and its contribution to the therapeutic effect) .
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Hydrological niches of plants vary with increasing complexity of interspecific competition...
Time of Update: 2022-05-20
The results show that each species in different plant communities has a relatively favorable depth of underground resource utilization in a certain period of time, thus showing a higher competitive advantage relative to its neighboring species .
