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The largest and most comprehensive single-cell profile of tumor infiltration B cells and plasma cells to date
Time of Update: 2022-09-20
Dr. Linghua Wang Image credit: MD Anderson Cancer CenterThrough extensive single-cell analysis, researchers at the University of Texas MD Anderson Cancer Center have created spatial maps of tumor-infiltrated B cells and plasma cells in early lung cancer, highlighting the previously unappreciated role these immune cells play in tumor development and treatment outcomes.
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Zhang Junlong's research group, Chen Xing's research group and collaborators reported that the new biological orthogonal rare earth molecular probes are used for near-infrared fluorescence/mass spectrometry imaging
Time of Update: 2022-09-20
" Spectrometry Imaging" research paper and was selected as a VIP (very important paper) paper 。 The work reported the first bio-orthogonal, high-brightness near-infrared (NIR) rare earth complex molecular probe, which specifically labeled multiple types of biological macromolecules in cells through metabolic labeling strategies and click chemistry reactions, achieved multicolor imaging and click chemistry-based expansion microscopy imaging (Click-ExM), and successfully combined NIR fluorescence imaging and mass spectrometry imaging to achieve bimodal imaging at subcellular resolution.
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Nature creates artificial cells with realistic functions!
Time of Update: 2022-09-20
”Living material assembly of bacteriogenic protocells Scientists have harnessed the potential of bacteria to help build advanced synthetic cells that mimic real-life functions.
”Living material assembly of bacteriogenic protocells Scientists have harnessed the potential of bacteria to help build advanced synthetic cells that mimic real-life functions.
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Scientists have finally solved the mystery of "cross-pollination": genes that determine the length of organs
Time of Update: 2022-09-20
Genomic analyses of the Linum distyly supergene reveal convergent evolution at the molecular level Scientists have solved a century-old mystery: a super-gene that can cause effective cross-pollination in flowers.
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$1.9 million: Study of neuronal activity in the central taste area of the brain
Time of Update: 2022-09-20
"It's important to understand its neural tissue in order to gain new insights into how the brain controls eating behavior.
"It's important to understand its neural tissue in order to gain new insights into how the brain controls eating behavior.
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Science Advances: Peking University scholars have discovered a new type of electrical signal that maintains a circadian rhythm
Time of Update: 2022-09-20
On September 2, 2022, Luo Donggen's team from the Beijing University Of Sciences, the McGovern Brain Research Institute, the Center for Quantitative Biology, and the Joint Center for Life Sciences pub
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Why does the heat make people feel inspirant?
Time of Update: 2022-09-20
”References:A thermometer circuit for hot temperature adjusts Drosophila behavior to persistent heat A study of fruit flies revealed that brain circuits facilitate midday naps on hot days.
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Chinese scholars and overseas collaborators have made progress in climate change and feedback mechanisms for the potential of biomass energy emission reductions
Time of Update: 2022-09-20
To meet the Paris Agreement target of limiting warming to 2°C by the end of the century, many future emission reduction scenarios assume that they will exceed the established temperature target in the short term, and short-term climate reductions will be achieved in the second half of this century through the implementation of large-scale biomass energy with carbon capture and storage (BECCS).
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How many years does it take eLife for plants to "collaborate"?
Time of Update: 2022-09-20
eLife, 2022 Growing multiple food crops at the same time is a more sustainable agricultural practice that mimics high-yielding wild plant communities.
eLife, 2022 Growing multiple food crops at the same time is a more sustainable agricultural practice that mimics high-yielding wild plant communities.
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【Scientific research dynamics】Professor Guo Anyuan's team recently published a number of achievements in the field of tumor immunotherapy
Time of Update: 2022-09-20
On September 12, 2022, Professor Guo Anyuan of the School of Life Sciences of Huazhong University of Science and Technology published a book entitled "ICBatlas: A comprehensive resource for depicting immune" in Cancer Immunology Research, a prestigious journal of the American Association for Cancer Research (AACR).
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Cell Discovery's Fu Hui Tang/Fu Wei research group collaborated to reveal the tumorigenesis mechanism of small bowel cancer
Time of Update: 2022-09-20
On September 14, 2022, the Tang Fuhui team of the Biomedical Frontier Innovation Center (BIOPIC) of Peking University worked closely with the Fu Wei team of general surgery of the Third Hospital of Beijing Medical University to publish a paper entitled Single-cell profiling reveals molecular basis of malignant phenotypes and tumor microenvironments in Small bowel adenocarcinomas research paper.
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Research shows that natural disasters can cause unseen damage to our brains
Time of Update: 2022-09-20
Japanese researchers monitored the National Health Insurance Claims Database for the year before and after the 2018 Floods in Japan and found an increase in prescriptions for acute migraines in the worst-hit southwestern counties, suggesting an increase in the frequency and severity of attacks of this debilitating neurological disorder in the wake of natural disasters.
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Chinese scholars have made progress in the field of organic conductive polymers
Time of Update: 2022-09-20
Fig. 1 Synthesis mechanism diagram of conductive polymer PBFDO Figure 2 Application of PBFDO in organic electronic devices. (a-c) organic and electrical transistors; (d,e) Organic thermoelectric gene
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Nature Metabolism, the University of Science and Technology of China, published an article reporting on the neural mechanisms of alcohol and cannabis synergy that lead to dyskinesia
Time of Update: 2022-09-20
Psychoactive drugs such as alcohol and tetrahydrocannabinol Δ9-tetrahydrocannabinol (THC), are widely reported to cause dyskinesia by targeting the central nervous system. Numerous international stud
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Chinese scholars have made important progress in the research of high-density photoelectric computing devices
Time of Update: 2022-09-20
Figure 1 Based on ENZ metamaterial differentiator and integrator: (A) differential differentiator structure diagram; (B) Integrator structure diagram; (C) Gaussian pulse through the differential oper
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Insects have a hard time adapting to extreme temperatures, which makes them vulnerable to the effects of climate change
Time of Update: 2022-09-20
As increasingly frequent and intense heat waves expose animals to temperatures beyond normal limits, an international team led by researchers at the University of Bristol studied more than 100 species of insects to better understand how these changes might affect them.
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Cell: Bacteria that were previously considered harmless can actually worsen lung disease
Time of Update: 2022-09-20
Source: Cell Host & MicrobeA team of international scientists has found that a bacterium that lives in the human body: Neisseria is not as harmless as previously thought, and it can cause infections in patients with bronchiectasis, asthma and chronic obstructive pulmonary disease (COPD).
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Gao Xin's team at Suzhou Medical Institute proposed a new method to predict the efficacy of neoadjuvant chemotherapy for advanced gastric cancer
Time of Update: 2022-09-20
In the early stage, gao Xin's team from the Suzhou Institute of Medical Engineering of the Chinese Academy of Sciences and the Shanxi Provincial Cancer Hospital proposed for the first time a method for predicting the efficacy of neoadjuvant chemotherapy for advanced gastric cancer based on artificial intelligence (the relevant results were published in Lancet's EClinicalMedicine, 2022, 101348).
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The key to removing chlamydia infection from the human body
Time of Update: 2022-09-20
”In collaboration with Colleagues Raphael Valdivia and Robert Bastidas at Duke MGM University, the researchers conducted a large-scale genetic screening of chlamydia and found a protein, GarD (Gamma Resistance Determinant), that appears to block the ability of host cells to label chlamydia inclusions and be destroyed by the immune system.
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A new generation of intelligent fluorescence microscopes to detect rare biological events!
Time of Update: 2022-09-20
Yes, EPFL biophysicists did find a way to automatically control microscopic detailed imaging of biological events with the help of artificial neural networks, while limiting stress on the sample.
