-
【PHILIPS case per day】Subacute combined degeneration of the spinal cord
Time of Update: 2022-10-19
The following statements about subacute combined degeneration of the spinal cord are erroneous: Recently, Garcia Ortega and others from Murcia, Spain, published the following teaching case in AJNR magazine.
-
Front.aging neurosci-decreased exosomal acetylcholinesterase activity in plasma in patients with Parkinson's disease
Time of Update: 2022-10-19
The research team from the Seoul Veterans Health Service Medical Center in South Korea simultaneously tested the chromosomal markers of acetylcholinesterase (AChE) and α-syn, isolated exosomes from plasma samples from PD patients and healthy control group (HC) by ultracentrifugation, measured exosome AChE activity and α-syn levels, and explored their correlation with clinical parameters and their biomarkers.
-
【One case per day】Hepatoduodenal ligament intracellular schwannoma
Time of Update: 2022-10-19
【Case Introduction】:The patient, a 69-year-old woman, was admitted to hospital for "abdominal distension that worsens for more than 2 years". The patient had unprovoked abdominal distension 2 years ag
-
Neurology: Health-related quality of life in adults with classic subcurtain superficial ferrisosis: a cross-sectional study
Time of Update: 2022-10-19
Subcurial superficial ferrisis (iSS) is a rare but disabling neurological disorder characterized by progressive hearing loss, balance and mobility problems.
Subcurial superficial ferrisis (iSS) is a rare but disabling neurological disorder characterized by progressive hearing loss, balance and mobility problems.
-
Research status of urinary disorders in cerebral small vessel disease
Time of Update: 2022-10-19
The clinical characteristics of urination disorders in CSVD patients are mainly manifested as overactive bladder and urinary incontinence, and the mechanism is related to the damage in the structure and function of the frontal cortex, middle cingulate gyrus, and subcortical circuit.
-
JAMA Neurol: refractory status epilepticus may lead to cerebral atrophy
Time of Update: 2022-10-19
Researchers in the United States recently found that even if the seizures of ultra-refractory status epilepticus (SRSE) are controlled by anesthetic drugs, evidence of brain atrophy can still be seen on MRI.
-
Expert Review: How to better identify multi-system atrophy
Time of Update: 2022-10-19
Oligodendrocyte inclusion body formation is a characteristic pathologic change of the disease, and the early clinical manifestations are multisystem involvement, especially the early onset of severe autonomic dysfunction including urinary and cardiovascular systems.
-
100% functional improvement in Krabe's disease! A quick overview of the latest status of domestic research and development of AAV gene therapy
Time of Update: 2022-10-19
Ophthalmic diseasesIn the field of ophthalmic diseases, Newforth's launch pipeline NR082 (NFS-01) has made rapid progress, which uses rAAV2 as a carrier to deliver the engineered ND4 gene to the patient's damaged optic ganglion cells through intravitreal injection, repair the mitochondrial biological respiratory chain, and restore the vitality and visual function of optic ganglion cells.
-
Neurology: Alcohol consumption is a risk factor for acute stroke
Time of Update: 2022-10-19
High alcohol intake is consistently associated with all strokes, ischaemic strokes, and intracerebral haemorrhages.
high and moderate alcohol intake is associated with an increased chance of stroke, while low intake is not associated with stroke.
-
Express 66.4% of patients improved their symptoms! Myasthenia gravis drugs are submitted to the BLA
Time of Update: 2022-10-14
Developed by argenx with efgartigimod as the main active ingredient, Vyvgart was approved in December last year to treat adult myasthenia gravis patients with AChR antibody-positive intravenous injections once a week.
-
Talking about stroke prevention and treatment from multiple angles, the secretary general of the Shanghai Stroke Society said...
Time of Update: 2022-10-14
cn*For medical professionals onlyStroke, also known as acute cerebrovascular disease, is divided into hemorrhagic stroke and ischemic stroke, the most common of which is cerebral infarction.
cn*For medical professionals onlyStroke, also known as acute cerebrovascular disease, is divided into hemorrhagic stroke and ischemic stroke, the most common of which is cerebral infarction.
-
The Brain-Yi Chenju/Niu Jianqin team found that activating the Wnt/β-catenin pathway relieved blood-brain barrier dysfunction in Alzheimer's disease
Time of Update: 2022-10-14
Written by - Wang Qi, Su Yixun Editor-in-Charge - Wang Sizhen Editor - Xia YeAlzheimer's disease (AD) is a progressive neurodegenerative disease characterized by memory loss and cognitive impairment.
-
Relieves walking dysfunction and allows MS patients to regain their freedom and hope for World Walking Day
Time of Update: 2022-10-14
*For medical professionals onlyStandardized and scientific disease diagnosis and treatment management is an effective means to maximize the benefits of patients. Multiple sclerosis (MS), as a chronic
-
Neuron Cardiovascular Disease Affects Sleep! Academician Danyang's team reveals the mechanism by which the cardiovascular pressure reflex circuit regulates sleep
Time of Update: 2022-10-14
Interestingly, the chemical genetics or optogenetic activation of labeled NST neurons promotes non-REM sleep in addition to lowering blood pressure and heart rate.
Interestingly, the chemical genetics or optogenetic activation of labeled NST neurons promotes non-REM sleep in addition to lowering blood pressure and heart rate.
-
Early intervention, free and free - to protect the brain health of MS patients
Time of Update: 2022-10-14
Multiple sclerosis (MS) is a chronic autoimmune disease characterized by inflammation and neurodegeneration1. Brain atrophy, i. e. a gradual decrease in brain volume, reflects irreversible tissue dama
-
Acute cerebral infarction venous thrombolysis, must exclude such diseases!
Time of Update: 2022-10-14
Stroke simulation disease contains which diseases Common SMs include seizures, migraines, tumors, venous infarction, reversible posterior encephalopathy syndrome (PRES), and subdural edema.
Stroke simulation disease contains which diseases Common SMs include seizures, migraines, tumors, venous infarction, reversible posterior encephalopathy syndrome (PRES), and subdural edema.
-
Li Dan/Liu Cong's team discovered a new therapeutic target mediating neuroinflammation caused by Parkinson's disease α-syn fibers Cell Press Conversation Scientists
Time of Update: 2022-10-14
Life SciencesLife scienceOn September 20, 2022, the team of Professor Li Dan of Shanghai Jiao Tong University and the team of researcher Liu Cong of the Shanghai Institute of Organic Chemistry of the
-
Complement each other's strengths and complement each other's weaknesses, win-win cooperation! Scientists have revealed astrocytes and microglia "complementary" phagocytic synapses
Time of Update: 2022-10-14
Surprisingly, the P301S model mouse hippocampal brain region astrocytes have more phagocytic excitatory synapses and microglia more phagocytic inhibitory synapses.
Surprisingly, the P301S model mouse hippocampal brain region astrocytes have more phagocytic excitatory synapses and microglia more phagocytic inhibitory synapses.
-
Vertigo open "Betaestine" and pay attention to these 3 special groups!
Time of Update: 2022-10-14
Welcome to leave a message to tell the world small medicine Oh ~Evidence-based medicine, rational use of drugs[1-7][2-7] The anti-vertigoH3H3of patients [1, 3, 6, 7]H1H1H2[1] Drug information: Betadustine hydrochloride tablets, Lepu Hengjiuyuan Pharmaceutical Co.
-
Cell "nuclear antenna" cilia-serotonergic axonic synapses drive nuclear signals to alter chromatin accessibility
Time of Update: 2022-10-14
Clapham's team from the Janelia Research Park in the United States published an article titled A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin in the journal Cell on September 1, 2022 In accessibility's article, they demonstrate the synaptic structure between the brainstem serotonergic axons and the primary cilia of hippocampal CA1 pyramidal neurons, which are rich in cilia-limiting serotonin receptor 5-HTR6, which activates the non-classical Gαq/11-RhoA pathway that modulates nuclear actin and increases histone acetylation and chromatin accessibility.
