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AGING CELL: The team found that the longevity gene Klotho improves the removal and cognition of A-beta in Alzheimer's disease.
Time of Update: 2020-10-05
studies have shown that A-beta activates NACHT, LRR, and PYD-containing protein 3 (NLRP3) inflammatory bodies, mediates the transition of small glial cells from M2 to M1, reducing the removal of A-beta.
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Stroke: Electro-encephalograms may improve the diagnosis of acute stroke and large vascular closure.
Time of Update: 2020-10-05
patients who were treated in the emergency department and were suspected of acute stroke (n-100) were clinically examined and then electroencephalograms were performed using a dry electrode system.
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DC2020: Li Zi pay, cerebrovascular interventional treatment progress.
Time of Update: 2020-10-05
This year, the Forum to "pick up the grade, the new journey" as the theme, continue to pay attention to China's medical device industry ecological development, the latest changes in industry policy; on September 18th, Li Zihua, deputy director of Shanghai Changhai Hospital, delivered a speech on the theme of "Progress in Cerebrovascular Interventional Therapy".
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JNNP: Mutations in RNF170 lead to resonant co-dysfunction neuropathy in the foretrial reflex disorder.
Time of Update: 2020-10-05
this may be the cause of the family's normal chromosomal explicit genetic sensory disorder neuropathy.
However, both clinical esoterics mainly involve upper motor neurons and back-root nerve-section sensory neurons, and involve pathogenic mechanisms, and the loss of function and toxicity between RNF170 HSP and normal chromosomal explicit sensory disorders are different.
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JNNP: Overexcitement of split hand motor axons in spinal myeloid amyotrophic disorder.
Time of Update: 2020-10-05
results show that hand fractures are often found not only in ALS but also in SBMA patients using quantitative CMAP analysis, suggesting that both diseases have the same pathophysiology of motor neuron death.
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Cell Death Dis: 菪 improves the survival of dopamine-energy neurons.
Time of Update: 2020-10-05
in the PD fruit fly genetic model, Sp can restore redox balance, mitochondrial function and prevent oxidative damage, and ultimately promote the recovery of dopamine neural networks and motor ability.
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JNNP: Neuronal surface antibody syndrome is common in children with narcolepsy and motor disorders.
Time of Update: 2020-10-05
cell tests of specific antigens were performed on NT1 patients and control group serums.
presence of motor disorders can guide serum and cerebrospinal fluid antibody testing in children's narcolepsy prospective studies to confirm these new findings and consider their significance.
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NEJM: Granuloma amiba encephalitis - case reported.
Time of Update: 2020-10-05
the cerebrospinal fluid culture negative, cytological analysis did not see malignant cells.
MRI examination after 2 days and found larger lesions in the frontal, top and temporal lobes, accompanied by lumps (figure B).
amiba is transmitted through contact with soil or fresh water.
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Lancet Neurology: The safety, toeration and effectiveness of oral Atogepant treatment for thyset migraines in adults: a double-blind, randomized phase 2b/3 trial.
Time of Update: 2020-10-05
Atogepant is an oral small molecule calcitonin gene-associated peptide (CGRP) peptide antagonist, and a series of studies have been published on Atogepant's treatment of migraines.
Safety, tolerability, and efficacy of orally agency atogepant for the prevention of episodic migraine in adults: a double-blind, randomized phase 2b/3 trial Goadsby, Peter J et al.
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Behavioural Brain Research: 7 weeks of intensive meditation training causes cerebral cortique recombination in beginners.
Time of Update: 2020-10-05
Recent functional magnetic resonance imaging studies have shown that decreased activity in dmN brain regions, including front buckles back to the cortical layer, shuttle back, mid-temporal refracts, and pre-protrusions, may promote the selectivity of synapses dependent on use during meditation, leading to GM reduced mPFC.
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JAHA: Mid-layer thickness of the endometrium of the carotid artery and risk of sudden cardiac death.
Time of Update: 2020-10-05
an average of 23.5 years of follow-up, 569 participants in the ARIC study had SCDs (1.81 cases per 1,000 people per year).
plaque was associated with a 35% increase in SCD risk: HR (95%CI) in the ARIC study was 1.37 (1.13-1.67) and CHS was 1.32 (1.04-1.68).
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Wang Congjun: China's stroke report released in 2019.
Time of Update: 2020-10-05
The report aims to describe the epidemiological status and risk factors of stroke in urban and rural residents in China, the incidence of stroke patients, clinical characteristics, diagnosis and treatment processes and hospital outcomes and other disease occurrence and quality of medical care indicators, will better prevent disease occurrence, rapid and efficient diagnosis and treatment, improve the quality of medical care, optimize the allocation of resources and formulate relevant health and research policies to provide scientific data and information support.
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Sci Rep's new discovery! There is a strong correlation between physical activity or brain memory performance!
Time of Update: 2020-10-05
() References: 1 Sport and memory go hand in handby University of Geneva 2 Blanca Marin Bosch et al, Effect of acute physical exercise on motor sequence memory, Scientific Reports (2020).
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J Neurosci: Key proteins regulate brain development.
Time of Update: 2020-10-05
next, the researchers asked how inflammation increased in the brains of newborn mice that lacked PRMT1 and looked closely at asstary and small glial cells.
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Focus on brain health! These research results are worth reading!
Time of Update: 2020-10-05
The prevalence of the COVID-19 outbreak dramatically shows how important it is for humans to get rid of their habits and learn new ones, and that animals must be able to adapt quickly to changes in environmental conditions; in a recent study published in the international journal Nature, scientists from institutions such as the University of Zurich in Switzerland found that reprogramming brain cells may help the body make more flexible decisions.
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Sci Signal: Drinking alcohol causes small glial cells to activate, disrupts nerve transmission in the brain, and triggers anxiety.
Time of Update: 2020-10-05
study found that alcoholism in male mice induced small glial cells to selectively remove excitable synapses between neurons in the pre-cortical cortical layer, thereby suppressing nerve conduction and increasing anxiety behavior.
the activity of small glial cells reduces synapses between neurons in the pre-cortical cortical layer of the brain, inhibits nerve transductivity, and causes anxiety.
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Diabetes Care: The relationship between sugar-lowering drugs and the incidence of depression.
Time of Update: 2020-10-05
a recent study published in Diabetes Care, an authoritative journal in the field of diabetes, researchers teamed up with four Danish-based registries to find out whether 20 widely used oral antisaccharies were associated with a risk of depression.
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Acta Neuropathologica: The relationship between possible REM sleep behavior disorders and pathology and exposure to exercise years in patients with chronic traumatic encephalopathy.
Time of Update: 2020-10-05
Repeated head impacts (RHI) and mild traumatic brain injury (TBI) associated with neurodegenerative chronic traumatic encephalopathy (CTE) through contact with movement or exposure to military shock waves.
, pRBD in CTE was associated with an increase in the number of years of exercise, and possibly to Louisian and brain-dry tau pathology.
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Front Aging Neurosci: Fructose in the brain causes Alzheimer's disease.
Time of Update: 2020-10-05
the study, published in the journal Frontiers in Aging Neuroscience, makes the hypothesis that Alzheimer's disease is largely driven by Western culture and is influenced by excessive fructose metabolism in the brain.
theory, enzymes that inhibit fructose production or metabolism in the brain may provide new ways to prevent and treat Alzheimer's disease.
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EPX-100 Treatment of Dravet Syndrome: Phase II research has been initiated.
Time of Update: 2020-10-05
biopharmaceutical company, Epigenix Therapeutics, recently announced that it has launched a multi-center, randomized, double-blind, placebo-controlled concept validation trial for EPX-100 to treat children with Dravet syndrome.
phase II study will confirm the efficacy and safety of EPX-100 in children with Dravet syndrome.
